Clinical Influence of Cervical Spinal Canal Stenosis on Neurological Outcome after Traumatic Cervical Spinal Cord Injury without Major Fracture or Dislocation

Study DesignRetrospective case series.PurposeTo clarify the influence of cervical spinal canal stenosis (CSCS) on neurological functional recovery after traumatic cervical spinal cord injury (CSCI) without major fracture or dislocation.Overview of LiteratureThe biomechanical etiology of traumatic CSCI remains under discussion and its relationship with CSCS is one of the most controversial issues in the clinical management of traumatic CSCI.MethodsTo obtain a relatively uniform background, patients non-surgically treated for an acute C3–4 level CSCI without major fracture or dislocation were selected. We analyzed 58 subjects with traumatic CSCI using T2-weighted mid-sagittal magnetic resonance imaging. The sagittal diameter of the cerebrospinal fluid (CSF) column, degree of canal stenosis, and neurologic outcomes in motor function, including improvement rate, were assessed.ResultsThere were no significant relationships between sagittal diameter of the CSF column at the C3–4 segment and their American Spinal Injury Association motor scores at both admission and discharge. Moreover, no significant relationships were observed between the sagittal diameter of the CSF column at the C3–4 segment and their neurological recovery during the following period.ConclusionsNo relationships between pre-existing CSCS and neurological outcomes were evident after traumatic CSCI. These results suggest that decompression surgery might not be recommended for traumatic CSCI without major fracture or dislocation despite pre-existing CSCS

合併症を有するB型大動脈解離に対するステントグラフト内挿術における腎動脈に対する治療戦略 : 多施設共同研究

Background: Management of abdominal branches associated with Stanford type B aortic dissection is controversial without definite criteria for therapy after thoracic endovascular aortic repair (TEVAR). This is in part due to lack of data on natural history related to branch vessels and their relationship with the dissection flap, true lumen, and false lumen. Purpose: To investigate the natural history of abdominal branches after TEVAR for type B aortic dissection and the relationship between renal artery anatomy and renal volume as a surrogate measure of perfusion. Materials and Methods: This study included patients who underwent TEVAR for complicated type B dissection from January 2012 to March 2017 at 20 centers. Abdominal aortic branches were classified with following features: patency, branch vessel origin, and presence of extension of the aortic dissection into a branch (pattern 1, supplied by the true lumen without branch dissection; pattern 2, supplied by the true lumen with branch dissection, etc). The branch artery patterns before TEVAR were compared with those of the last follow-up CT (mean interval, 19.7 months) for spontaneous healing. Patients with one kidney supplied by pattern 1 and the other kidney by a different pattern were identified, and kidney volumes over the course were compared by using a simple linear regression model. Results: Two hundred nine patients (mean age ± standard deviation, 66 years ± 13; 165 men and 44 women; median follow-up, 18 months) were included. Four hundred fifty-nine abdominal branches at the last follow-up were evaluable. Spontaneous healing of the dissected branch occurred in 63% (64 of 102) of pattern 2 branches. Regarding the other patterns, 6.5% (six of 93) of branches achieved spontaneous healing. In 79 patients, renal volumes decreased in kidneys with pattern 2 branches with more than 50% stenosis and branches supplied by the aortic false lumen (patterns 3 and 4) compared with contralateral kidneys supplied by pattern 1 (pattern 2 vs pattern 1: −16% ± 16 vs 0.10% ± 11, P = .002; patterns 3 and 4 vs pattern 1: −13% ± 14 vs 8.5% ± 14, P = .004). Conclusion: Spontaneous healing occurs more frequently in dissected branches arising from the true lumen than in other branch patterns. Renal artery branches supplied by the aortic false lumen or a persistently dissected artery with greater than 50% stenosis are associated with significantly greater kidney volume loss.博士（医学）・乙第1461号・令和2年6月30日Copyright © 2019 by authors and RSNA. This work is licensed under the Creative Commons Attribution International License (CC BY-NC-ND 4.0). https://creativecommons.org/licenses/by-nc-nd/4.0/

RFLP(制限酵素DNA断片長多型)を利用したイネの連鎖地図作成に関する研究

第1章 トリソミックスを利用したRFLPクローンの座乗染色体決定ならびにRFLP分析による異数体の染色体構造の決定 第2章 従来の連鎖地図とRFLP連鎖地図との統合 第3章 総合考察Made available in DSpace on 2012-09-06T04:10:28Z (GMT). No. of bitstreams: 2 ideta1.pdf: 12893703 bytes, checksum: 2c035d5eca87aa01d4ae2d31493e02e7 (MD5) ideta2.pdf: 11873628 bytes, checksum: 59841545fb29bae78d5fd0b642994e75 (MD5) Previous issue date: 1996-03-13主1-参

Yield and Lodging Resistance of ‘Tachiayaka’, a Novel Rice Cultivar with Short Panicles for Whole-Crop Silage

Abstract: ‘Tachiayaka’ is a novel cultivar of rice (Oryza sativa L.) with short panicles that is suitable for use in whole-crop silage. It was selected from bulked progeny obtained from two backcrosses of ‘Hoshiaoba’ to F1 plants of ‘Chugoku 146’ (‘Hoshiaoba’) × ‘Gokutansui (00kosen11)’. The unhulled rice yield of ‘Tachiayaka’ was comparable to that of ‘Tachisuzuka’, a short-panicle cultivar with high digestibility in cattle, in multi-location trials over a wide area spanning the Hokuriku to Chugoku regions in Japan. The whole-crop yield and the maturity of ‘Tachiayaka’ were comparable to those of ‘Hoshiaoba’. These findings indicated the suitability of ‘Tachiayaka’ for cultivation across a wide area of Japan. The characters associated with lodging resistance in ‘Tachiayaka’, including lodging index, were superior to those of ‘Hoshiaoba’. The high lodging resistance of ‘Tachiayaka’ will enable its cultivation in regions where lodging occurs frequently

Trajectories of the influence of the days to heading (DH) on culm length (CL) estimated by the nonlinear structural equation (NSE) in the simulation analyses.

<p>We conducted three simulation schemes: “Nonlinear influence” where the nonlinear influences of DH on CL estimated in the real data analyses were used to simulate data sets; “Linear influence” where the influence was set to 1.2 for all DH values; and “No influence” where there was assumed to be no influence (i.e., zero). In each scheme, 20 data sets were simulated using the real data analysis results at each location and analyzed using the NSE. In each scheme at each location, the estimated trajectories of the influence of DH are superimposed with gray lines, and the true trajectory (value) of the influence is indicated by the red line. The dashed lines indicate zero (no influence).</p

Uncovering a Nuisance Influence of a Phenological Trait of Plants Using a Nonlinear Structural Equation: Application to Days to Heading and Culm Length in Asian Cultivated Rice (<i>Oryza Sativa</i> L.)

<div><p>Phenological traits of plants, such as flowering time, are linked to growth phase transition. Thus, phenological traits often influence other traits through the modification of the duration of growth period. This influence is a nuisance in plant breeding because it hampers genetic evaluation of the influenced traits. Genetic effects on the influenced traits have two components, one that directly affects the traits and one that indirectly affects the traits via the phenological trait. These cannot be distinguished by phenotypic evaluation and ordinary linear regression models. Consequently, if a phenological trait is modified by introgression or editing of the responsible genes, the phenotypes of the influenced traits can change unexpectedly. To uncover the influence of the phenological trait and evaluate the direct genetic effects on the influenced traits, we developed a nonlinear structural equation (NSE) incorporating a nonlinear influence of the phenological trait. We applied the NSE to real data for cultivated rice (<i>Oryza sativa</i> L.): days to heading (DH) as a phenological trait and culm length (CL) as the influenced trait. This showed that CL of the cultivars that showed extremely early heading was shortened by the strong influence of DH. In a simulation study, it was shown that the NSE was able to infer the nonlinear influence and direct genetic effects with reasonable accuracy. However, the NSE failed to infer the linear influence in this study. When no influence was simulated, an ordinary bi-trait linear model (OLM) tended to infer the genetic effects more accurately. In such cases, however, by comparing the NSE and OLM using an information criterion, we could assess whether the nonlinear assumption of the NSE was appropriate for the data analyzed. This study demonstrates the usefulness of the NSE in revealing the phenotypic influence of phenological traits.</p></div