The surface energy balance during foehn events at Joyce Glacier, McMurdo Dry Valleys, Antarctica

The McMurdo Dry Valleys (MDV) are a polar desert, where glacial melt is the main source of water to streams and the ecosystem. Summer air temperatures are typically close to zero, and therefore foehn events can have a large impact on the meltwater production. A 14-month record of automatic weather station (AWS) data on Joyce Glacier is used to force a 1D surface energy balance model to study the impact of foehn events on the energy balance. AWS data and output of the Antarctic Mesoscale Prediction System (AMPS) on a 1.7 km grid are used to detect foehn events at the AWS site. Foehn events at Joyce Glacier occur under the presence of cyclones over the Ross Sea. The location of Joyce Glacier on the leeward side of the Royal Society Range during these synoptic events causes foehn warming through isentropic drawdown. This mechanism differs from the foehn warming through gap flow that was earlier found for other regions in the MDV and highlights the complex interaction of synoptic flow with local topography of the MDV. Shortwave radiation is the primary control on melt at Joyce Glacier, and melt often occurs with subzero air temperatures. During foehn events, melt rates are enhanced, contributing to 23 % of the total annual melt. Foehn winds cause a switch from a diurnal stability regime in the atmospheric surface layer to a continuous energy input from sensible heat flux throughout the day. The sensible heating during foehn, through an increase in turbulent mixing resulting from gustier and warmer wind conditions, is largely compensated for by extra heat losses through sublimation. Melt rates are enhanced through an additional energy surplus from a reduced albedo during foehn.</p

Office-based optical coherence tomographic imaging of human vocal cords

Optical coherence tomography (OCT) is an evolving noninvasive imaging modality and has been used to image the larynx during surgical endoscopy. The design of an OCT sampling device capable of capturing images of the human larynx during a typical office based laryngoscopy examination is discussed. Both patient’s and physician\u27s movements were addressed. In vivo OCT imaging of the human larynx is demonstrated. Though the long focal length limits the lateral resolution of the image, the basement membrane can still be readily distinguished. Office-based OCT has the potential to guide surgical biopsies, direct therapy, and monitor disease. This is a promising imaging modality to study the larynx

Rothamsted Conference RC No 8: Recent changes in systems of husbandy in Engand

RESP-60

The surface energy balance during foehn events at Joyce Glacier, McMurdo Dry Valleys, Antarctica

The McMurdo Dry Valleys (MDV) are a polar desert, where glacial melt is the main source of water to streams and the ecosystem. Summer air temperatures are typically close to zero, and therefore foehn events can have a large impact on the meltwater production. A 14-month record of automatic weather station (AWS) data on Joyce Glacier is used to force a 1D surface energy balance model to study the impact of foehn events on the energy balance. AWS data and output of the Antarctic Mesoscale Prediction System (AMPS) on a 1.7 km grid are used to detect foehn events at the AWS site. Foehn events at Joyce Glacier occur under the presence of cyclones over the Ross Sea. The location of Joyce Glacier on the leeward side of the Royal Society Range during these synoptic events causes foehn warming through isentropic drawdown. This mechanism differs from the foehn warming through gap flow that was earlier found for other regions in the MDV and highlights the complex interaction of synoptic flow with local topography of the MDV. Shortwave radiation is the primary control on melt at Joyce Glacier, and melt often occurs with subzero air temperatures. During foehn events, melt rates are enhanced, contributing to 23 % of the total annual melt. Foehn winds cause a switch from a diurnal stability regime in the atmospheric surface layer to a continuous energy input from sensible heat flux throughout the day. The sensible heating during foehn, through an increase in turbulent mixing resulting from gustier and warmer wind conditions, is largely compensated for by extra heat losses through sublimation. Melt rates are enhanced through an additional energy surplus from a reduced albedo during foehn

Genes That Influence Swarming Motility and Biofilm Formation in Variovorax paradoxus EPS

Variovorax paradoxus is an aerobic soil bacterium associated with important biodegradative processes in nature. We use V. paradoxus EPS to study multicellular behaviors on surfaces.We recovered flanking sequence from 123 clones in a Tn5 mutant library, with insertions in 29 different genes, selected based on observed surface behavior phenotypes. We identified three genes, Varpa_4665, Varpa_4680, and Varpa_5900, for further examination. These genes were cloned into pBBR1MCS2 and used to complement the insertion mutants. We also analyzed expression of Varpa_4680 and Varpa_5900 under different growth conditions by qPCR.The 29 genes we identified had diverse predicted functions, many in exopolysaccharide synthesis. Varpa_4680, the most commonly recovered insertion site, encodes a putative N-acetyl-L-fucosamine transferase similar to WbuB. Expression of this gene in trans complemented the mutant fully. Several unique insertions were identified in Varpa_5900, which is one of three predicted pilY1 homologs in the EPS genome. No insertions in the two other putative pilY1 homologs present in the genome were identified. Expression of Varpa_5900 altered the structure of the wild type swarm, as did disruption of the chromosomal gene. The swarming phenotype was complemented by expression of Varpa_5900 from a plasmid, but biofilm formation was not restored. Both Varpa_4680 and Varpa_5900 transcripts were downregulated in biofilms and upregulated during swarming when compared to log phase culture. We identified a putative two component system (Varpa_4664-4665) encoding a response regulator (shkR) and a sensor histidine kinase (shkS), respectively. Biofilm formation increased and swarming was strongly delayed in the Varpa_4665 (shkS) mutant. Complementation of shkS restored the biofilm phenotype but swarming was still delayed. Expression of shkR in trans suppressed biofilm formation in either genetic background, and partially restored swarming in the mutant.The data presented here point to complex regulation of these surface behaviors

A systematic review and meta-analysis of neurological soft signs in relatives of people with schizophrenia

<p>Abstract</p> <p>Background</p> <p>Neurological soft signs are subtle but observable impairments in motor and sensory functions that are not localized to a specific area of the brain. Neurological soft signs are common in schizophrenia. It has been established that soft signs meet two of five criteria for an endophenotype, namely: association with the illness, and state independence. This review investigated whether soft signs met a further criterion for an endophenotype, namely familial association. It was hypothesized that if familial association were present then neurological soft signs would be: (a) more common in first-degree relatives of people with schizophrenia than in controls; and (b) more common in people with schizophrenia than in their first-degree relatives.</p> <p>Method</p> <p>A systematic search identified potentially eligible studies in the EMBASE (1980-2011), OVID - MEDLINE (1950-2011) and PsycINFO (1806-2011) databases. Studies were included if they carried out a three-way comparison of levels of soft signs between people with schizophrenia, their first-degree relatives, and normal controls. Data were extracted independently by two reviewers and cross-checked by double entry.</p> <p>Results</p> <p>After screening 8678 abstracts, seven studies with 1553 participants were identified. Neurological soft signs were significantly more common in first-degree relatives of people with schizophrenia than in controls (pooled standardised mean difference (SMD) 1.24, 95% confidence interval (c.i) 0.59-1.89). Neurological soft signs were also significantly more common in people with schizophrenia than in their first-degree relatives (SMD 0.92, 95% c.i 0.64-1.20). Sensitivity analyses examining the effects of age and group blinding did not significantly alter the main findings.</p> <p>Conclusions</p> <p>Both hypotheses were confirmed, suggesting that the distribution of neurological soft signs in people with schizophrenia and their first-degree relatives is consistent with the endophenotype criterion of familial association.</p

Regenerative agriculture in Aotearoa New Zealand - research pathways to build science-based evidence and national narratives.

fals

Socio-cognitive scaffolding with collaboration scripts: a meta-analysis

Scripts for computer-supported collaborative learning (CSCL) offer socio-cognitive scaffolding for learners to engage in collaborative activities that are considered beneficial for learning. Yet, CSCL scripts are often criticized for hampering naturally emerging collaboration. Research on the effectiveness of CSCL scripts has shown divergent results. This article reports a meta-analysis about the effects of CSCL scripts on domain-specific knowledge and collaboration skills. Results indicate that CSCL scripts as a kind of socio-cognitive scaffolding can enhance learning outcomes substantially. Learning with CSCL scripts leads to a small positive effect on domain-specific knowledge (d = 0.20) and a large positive effect on collaboration skills (d = 0.95) compared to unstructured CSCL. Further analyses reveal that CSCL scripts are particularly effective for domain-specific learning when they prompt transactive activities (i.e., activities in which a learner’s reasoning builds on the contribution of a learning partner) and when they are combined with additional content-specific scaffolding (worked examples, concept maps, etc.). Future research on CSCL scripts should include measures of learners’ internal scripts (i.e., prior collaboration skills) and the transactivity of the actual learning process