Developing physical capability standards that are predictive of success on special forces selection courses

Free to read This study aimed to develop minimum standards for physical capability assessments (vertical jump, sit and reach, push-ups, seven-stage sit-ups, heaves, agility, 20-m shuttle run, loaded 5-km pack march, and 400-m swim) that candidates must pass before they can commence Australian Army Special Forces (SF) selection courses. Soldiers (Part A: n = 104; Part B: n = 92) completed the physical capability assessments before commencing a SF selection course. At the beginning of these selection courses, participants attempted two barrier assessments (3.2-km battle run and 20-km march). Statistical analysis revealed several physical capability assessments were associated with performance on the barrier assessments and selection course outcome (Part A); however, these statistical models were unable to correctly classify all candidates as likely to pass or fail the selection course. Alternatively, manual analysis identified a combination of physical capability standards that correctly classified 14% to 18% of candidates likely to fail, without excluding any candidates able to pass (Part A). The standards were applied and refined through Part B and included completing the 5-km pack march in ≤45:45 minutes : seconds, achieving ≥level five on the sit-up test, or completing ≥66 push-ups. Implementation of these standards may reduce attrition rates and enhance the efficiency of the SF recruitment process

The relationship between Hippocampal asymmetry and working memory processing in combat-related PTSD: a monozygotic twin study

BACKGROUND: PTSD is associated with reduction in hippocampal volume and abnormalities in hippocampal function. Hippocampal asymmetry has received less attention, but potentially could indicate lateralised differences in vulnerability to trauma. The P300 event-related potential component reflects the immediate processing of significant environmental stimuli and has generators in several brain regions including the hippocampus. P300 amplitude is generally reduced in people with PTSD. METHODS: Our study examined hippocampal volume asymmetry and the relationship between hippocampal asymmetry and P300 amplitude in male monozygotic twins discordant for Vietnam combat exposure. Lateralised hippocampal volume and P300 data were obtained from 70 male participants, of whom 12 had PTSD. We were able to compare (1) combat veterans with current PTSD; (2) their non-combat-exposed co-twins; (3) combat veterans without current PTSD and (4) their non-combat-exposed co-twins. RESULTS: There were no significant differences between groups in hippocampal asymmetry. There were no group differences in performance of an auditory oddball target detection task or in P300 amplitude. There was a significant positive correlation between P300 amplitude and the magnitude of hippocampal asymmetry in participants with PTSD. CONCLUSIONS: These findings suggest that greater hippocampal asymmetry in PTSD is associated with a need to allocate more attentional resources when processing significant environmental stimuli.Timothy Hall, Cherrie Galletly, C.R. Clark, Melinda Veltmeyer, Linda J. Metzger, Mark W. Gilbertson, Scott P. Orr, Roger K. Pitman and Alexander McFarlan

Linear stability, transient energy growth and the role of viscosity stratification in compressible plane Couette flow

Linear stability and the non-modal transient energy growth in compressible plane Couette flow are investigated for two prototype mean flows: (a) the {\it uniform shear} flow with constant viscosity, and (b) the {\it non-uniform shear} flow with {\it stratified} viscosity. Both mean flows are linearly unstable for a range of supersonic Mach numbers ($M$). For a given $M$, the critical Reynolds number ($Re$) is significantly smaller for the uniform shear flow than its non-uniform shear counterpart. An analysis of perturbation energy reveals that the instability is primarily caused by an excess transfer of energy from mean-flow to perturbations. It is shown that the energy-transfer from mean-flow occurs close to the moving top-wall for ``mode I'' instability, whereas it occurs in the bulk of the flow domain for ``mode II''. For the non-modal analysis, it is shown that the maximum amplification of perturbation energy, $G_{\max}$, is significantly larger for the uniform shear case compared to its non-uniform counterpart. For $\alpha=0$, the linear stability operator can be partitioned into ${\cal L}\sim \bar{\cal L} + Re^2{\cal L}_p$, and the $Re$-dependent operator ${\cal L}_p$ is shown to have a negligibly small contribution to perturbation energy which is responsible for the validity of the well-known quadratic-scaling law in uniform shear flow: $G(t/{\it Re}) \sim {\it Re}^2$. A reduced inviscid model has been shown to capture all salient features of transient energy growth of full viscous problem. For both modal and non-modal instability, it is shown that the {\it viscosity-stratification} of the underlying mean flow would lead to a delayed transition in compressible Couette flow

The Tropical Grassland Society of Australia Incorporated

The Tropical Grassland Society of Australia was formed in 1962 and became incorporated in 1987 and has the following aims: To publicise information of interest to primary producers and scientists To improve the relevance of research and adoption of technology through the flow of ideas between scientists and producers To publicise the findings of Australian pasture research and development to overseas workers, and to draw on their experience for application in Australi

Reduced dimensionality spin-orbit dynamics of CH3 + HCl reversible arrow CH4 Cl on ab initio surfaces

A reduced dimensionality quantum scattering method is extended to the study of spin-orbit nonadiabatic transitions in the CH3 + HCl reversible arrow CH4 + Cl(P-2(J)) reaction. Three two-dimensional potential energy surfaces are developed by fitting a 29 parameter double-Morse function to CCSD(T)/IB//MP2/cc-pV(T+d)Z-dk ab initio data; interaction between surfaces is described by geometry-dependent spin-orbit coupling functions fit to MCSCF/cc-pV(T+d)Z-dk ab initio data. Spectator modes are treated adiabatically via inclusion of curvilinear projected frequencies. The total scattering wave function is expanded in a vibronic basis set and close-coupled equations are solved via R-matrix propagation. Ground state thermal rate constants for forward and reverse reactions agree well with experiment. Multi-surface reaction probabilities, integral cross sections, and initial-state selected branching ratios all highlight the importance of vibrational energy in mediating nonadiabatic transition. Electronically excited state dynamics are seen to play a small but significant role as consistent with experimental conclusions. (C) 2011 American Institute of Physics. [doi:10.1063/1.3592732

Megachile (Megachile) montivaga (Hymenoptera: Megachilidae) nesting in live thistle (Asteraceae: Cirsium)

Although Megachile Latreille (leafcutter bees) are well known for their diverse nesting habits, records of the genus nesting in live plants are rare.  Here, we report the widespread Megachile (Megachile) montivaga Cresson nesting in live thistle (Cirsium neomexicanum Gray), the first explicit record of this behavior in the Nearctic

A combined molecular‐beam epitaxy and scanning tunneling microscopy system

A combined molecular‐beam epitaxy and scanning tunneling microscopy system has been constructed. The design has been optimized for the study of III‐V semiconductors with the goal of examining the surface with both in situ scanning tunneling microscopy (STM) and reflection high‐energy electron diffraction (RHEED). Using this system, it is possible to quench the growth and produce real‐space images of the surface as it appeared during deposition. Measurements obtained with both RHEED and STM are presented.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/70399/2/RSINAK-62-6-1400-1.pd

Role of PINCH and Its Partner Tumor Suppressor Rsu-1 in Regulating Liver Size and Tumorigenesis

Particularly interesting new cysteine-histidine-rich protein (PINCH) protein is part of the ternary complex known as the IPP (integrin linked kinase (ILK)-PINCH-Parvin-α) complex. PINCH itself binds to ILK and to another protein known as Rsu-1 (Ras suppressor 1). We generated PINCH 1 and PINCH 2 Double knockout mice (referred as PINCH DKO mice). PINCH2 elimination was systemic whereas PINCH1 elimination was targeted to hepatocytes. The genetically modified mice were born normal. The mice were sacrificed at different ages after birth. Soon after birth, they developed abnormal hepatic histology characterized by disorderly hepatic plates, increased proliferation of hepatocytes and biliary cells and increased deposition of extracellular matrix. After a sustained and prolonged proliferation of all epithelial components, proliferation subsided and final liver weight by the end of 30 weeks in livers with PINCH DKO deficient hepatocytes was 40% larger than the control mice. The livers of the PINCH DKO mice were also very stiff due to increased ECM deposition throughout the liver, with no observed nodularity. Mice developed liver cancer by one year. These mice regenerated normally when subjected to 70% partial hepatectomy and did not show any termination defect. Ras suppressor 1 (Rsu-1) protein, the binding partner of PINCH is frequently deleted in human liver cancers. Rsu-1 expression is dramatically decreased in PINCH DKO mouse livers. Increased expression of Rsu-1 suppressed cell proliferation and migration in HCC cell lines. These changes were brought about not by affecting activation of Ras (as its name suggests) but by suppression of Ras downstream signaling via RhoGTPase proteins. In conclusion, our studies suggest that removal of PINCH results in enlargement of liver and tumorigenesis. Decreased levels of Rsu-1, a partner for PINCH and a protein often deleted in human liver cancer, may play an important role in the development of the observed phenotype. © 2013 Donthamsetty et al

Structural and electrical transport properties of superconducting Au{0.7}In{0.3} films: A random array of superconductor-normal metal-superconductor (SNS) Josephson junctions

The structural and superconducting properties of Au{0.7}In{0.3} films, grown by interdiffusion of alternating Au and In layers, have been studied. The films were found to consist of a uniform solid solution of Au{0.9}In{0.1}, with excess In precipitated in the form of In-rich grains of various Au-In phases (with distinct atomic compositions), including intermetallic compounds. As the temperature was lowered, these individual grains became superconducting at a particular transition temperature (Tc), determined primarily by the atomic composition of the grain, before a fully superconducting state of zero resistance was established. From the observed onset Tc, it was inferred that up to three different superconducting phases could have formed in these Au{0.7}In{0.3} films, all of which were embedded in a uniform Au{0.9}In{0.1} matrix. Among these phases, the Tc of a particular one, 0.8 K, is higher than any previously reported for the Au-In system. The electrical transport properties were studied down to low temperatures. The transport results were found to be well correlated with those of the structural studies. The present work suggests that Au{0.7}In{0.3} can be modeled as a random array of superconductor-normal metal-superconductor (SNS) Josephson junctions. The effect of disorder and the nature of the superconducting transition in these Au{0.7}In{0.3} films are discussed.Comment: 8 text pages, 10 figures in one separate PDF file, submitted to PR

Nanoscale Morphology of Type I Collagen is Altered in the Brtl Mouse Model of Osteogenesis Imperfecta

Bone has a complex hierarchical structure that has evolved to serve structural and metabolic roles in the body. Due to the complexity of bone structure and the number of diseases which affect the ultrastructural constituents of bone, it is important to develop quantitative methods to assess bone nanoscale properties. Autosomal dominant Osteogenesis Imperfecta results predominantly from glycine substitutions (80%) and splice site mutations (20%) in the genes encoding the α1 or α2 chains of Type I collagen. Genotype-phenotype correlations using over 830 collagen mutations have revealed that lethal mutations are located in regions crucial for collagen-ligand binding in the matrix. However, few of these correlations have been extended to collagen structure in bone. Here, an atomic force microscopy-based approach was used to image and quantitatively analyze the Dperiodic spacing of Type I collagen fibrils in femora from heterozygous (Brtl/+) mice (α1(I)G349C), compared to wild type (WT) littermates. This disease system has a well-defined change in the col1α1 allele, leading to a well characterized alteration in collagen protein structure, which are directly related to altered Type I collagen nanoscale morphology, as measured by the Dperiodic spacing. In Brtl/+ bone, the D-periodic spacing shows significantly greater variability on average and along the length of the bone compared to WT, although the average spacing was unchanged. Brtl/+ bone also had a significant difference in the population distribution of collagen D-period spacings. These changes may be due to the mutant collagen structure, or to the heterogeneity of collagen monomers in the Brtl/+ matrix. These observations at the nanoscale level provide insight into the structural basis for changes present in bone composition, geometry and mechanical integrity in Brtl/+ bones. Further studies are necessary to link these morphological observations to nanoscale mechanical integrity