Have Cherenkov telescopes detected a new light boson?

Recent observations by H.E.S.S. and MAGIC strongly suggest that the Universe is more transparent to very-high-energy gamma rays than previously thought. We show that this fact can be reconciled with standard blazar emission models provided that photon oscillations into a very light Axion-Like Particle occur in extragalactic magnetic fields. A quantitative estimate of this effect indeed explains the observed data and in particular the spectrum of blazar 3C279.Comment: 3 pages, 1 figure, Proceeding of the "Eleventh International Workshop on Topics in Astroparticle and Underground Physics" (TAUP), Roma, Italy, 1 - 5 July 2009 (to be published in the Proceedings

Kac-Moody symmetry in the light front of gauge theories

We discuss the emergence of a new symmetry generator in a Hamiltonian realisation of four-dimensional gauge theories in the flat space foliated by retarded (advanced) time. It generates an asymptotic symmetry that acts on the asymptotic fields in a way different from the usual large gauge transformations. The improved canonical generators, corresponding to gauge and asymptotic symmetries, form a classical Kac-Moody charge algebra with a non-trivial central extension. In particular, we describe the case of electromagnetism, where the charge algebra is the $\mathrm{U}(1)$ current algebra with a level proportional to the coupling constant of the theory, $\kappa=4\pi^2/e^2$. We construct bilinear generators yielding Virasoro algebras on the null boundary. We also provide a non-Abelian generalization of the previous symmetries by analysing the evolution of Yang-Mills theory in Bondi coordinates.Comment: 31 pages, no figures; in V2 text clarified and references adde

Infant mortality rates and pneumococcal vaccines: a time-series trend analysis in 194 countries, 1950–2020

Pneumonia due to Streptococcus pneumoniae (pneumococcus) is a major cause of mortality in infants (children under 1 year of age), and pneumococcal conjugate vaccines (PCVs), delivered during the first year of life, are available since the year 2000. Given those two premises, the conclusion follows logically that favourable impact reported for PCVs in preventing pneumococcal disease should be reflected in the infant mortality rates (IMRs) from all causes. Using publicly available datasets, country-level IMR estimates from UNICEF and PCV introduction status from WHO, country-specific time series analysed the temporal relationship between annual IMRs and the introduction of PCVs, providing a unique context into the long-term secular trends of IMRs in countries that included and countries that did not include PCVs in their national immunisation programmes. PCV status was available for 194 countries during the period 1950–2020: 150 (77.3%) of these countries achieved nationwide PCV coverage at some point after the year 2000, 13 (6.7%) achieved only partial or temporary PCV coverage, and 31 (15.9%) never introduced PCVs to their population. One hundred and thirty-nine (92.7%) of countries that reported a decreasing (negative) trend in IMR, also reported a strong correlation with decreasing maternal mortality rates (MMRs), suggesting an improvement in overall child/ mother healthcare. Conversely, all but one of the countries that never introduced PCVs in their national immunisation programme also reported a decreasing trend in IMR that strongly correlates with MMRs. IMRs have been decreasing for decades all over the world, but this latest decrease may not be related to PCVs

Infant mortality rates and pneumococcal vaccines: a time-series trend analysis in 194 countries, 1950–2020

Pneumonia due to Streptococcus pneumoniae (pneumococcus) is a major cause of mortality in infants (children under 1 year of age), and pneumococcal conjugate vaccines (PCVs), delivered during the first year of life, are available since the year 2000. Given those two premises, the conclusion follows logically that favourable impact reported for PCVs in preventing pneumococcal disease should be reflected in the infant mortality rates (IMRs) from all causes. Using publicly available datasets, country-level IMR estimates from UNICEF and PCV introduction status from WHO, country-specific time series analysed the temporal relationship between annual IMRs and the introduction of PCVs, providing a unique context into the long-term secular trends of IMRs in countries that included and countries that did not include PCVs in their national immunisation programmes. PCV status was available for 194 countries during the period 1950–2020: 150 (77.3%) of these countries achieved nationwide PCV coverage at some point after the year 2000, 13 (6.7%) achieved only partial or temporary PCV coverage, and 31 (15.9%) never introduced PCVs to their population. One hundred and thirty-nine (92.7%) of countries that reported a decreasing (negative) trend in IMR, also reported a strong correlation with decreasing maternal mortality rates (MMRs), suggesting an improvement in overall child/ mother healthcare. Conversely, all but one of the countries that never introduced PCVs in their national immunisation programme also reported a decreasing trend in IMR that strongly correlates with MMRs. IMRs have been decreasing for decades all over the world, but this latest decrease may not be related to PCVs

Herd immunity in older adults from a middle-income country: A time-series trend analysis of community-acquired pneumonia mortality 2003–2017

Background and Aims: Community-acquired pneumonia is responsible for substantial mortality, and pneumococcus is commonly accepted as a major cause of pneumonia, regardless of laboratory confirmation. Child immunization programs have reported success in decreasing pneumonia mortality: directly in young children and indirectly (herd immunity) in unvaccinated adult populations in some countries. We assess changes in mortality trends for all-cause pneumonia in older adults associated with the introduction of pneumococcal vaccination for children in Peru. Methods: This is a secondary analysis on administrative data collected periodically by the Peruvian Ministry of Health. An observational retrospective time series analysis was conducted using longitudinal population-based data from death certificates in Peru between 2003 and 2017. The time series includes 6 years before and 9 years after the introduction of the pneumococcal-conjugated vaccines in the national child immunization program in 2009. Monthly frequencies and annual rates for all-cause pneumonia deaths in children under 5 years of age and adults over 65 years of age are presented. Linear and quadratic trends are analyzed. Results: Deaths among older adults accounted for 75.6% of all-cause pneumonia mortality in Peru, with 94.4% of these reporting “pneumonia due to unspecified organism” as the underlying cause of death. Comparing pre- and post-child immunization program periods, annual average mortality rates from unspecified pneumonia decreased by 22.7% in young children but increased by 19.6% in older adults. A linear trend model supports this overall tendency, but a quadratic curve explains the data better. Conclusion: Pneumococcal-conjugated vaccines are developed using serotypes prevalent in selected countries from less common (invasive) pneumococcal disease and expected to prevent mortality worldwide from widespread (noninvasive) pneumonia. Our results do not support the presence of herd immunity from pneumococcal vaccination of children for community-acquired pneumonia in the increasingly ageing population of Peru. This should direct future research and could influence public health policy.Revisión por pare

Linear and Nonlinear Spectroscopy by a Common-Path Birefringent Interferometer

© 1995-2012 IEEE. We introduce a passive common-path interferometer to replace Michelson interferometers in the Fourier-Transform spectroscopy. Our device exploits birefringence to introduce a highly accurate delay between two orthogonal polarization components by continuously varying the material thickness. Due to its inherent delay stability and reproducibility, it can be used even for short wavelengths (down to ∼200 nm) without the need for any active control or position tracking. We first demonstrate its performances in linear spectroscopy, by implementing a spectrometer and a spectrophotometer. We then extend its use to nonlinear spectroscopy and, in combination with lock-in detection at MHz modulation frequencies, illustrate its application to pump-probe spectroscopy with high sensitivity (ΔT/T 500 nm) and to broadband stimulated Raman scattering microscopy in the CH stretching region

Assessing the Potential of Sensors Based on LbL and Sputtering Films

Funding text This research was funded by the project PCIF/GFC/0078/2018: influence of forest VOCs (volatile organic compounds) on extreme fire behavior at Fundação para a Ciência e a Tecnologia (FCT). The authors also thankful for the research center grants no. UIDB/FIS/04559/2020 and no. UIDP/FIS/04559/2020 (LIBPhys) from FCT/MCTES, Portugal.A new theory suggests that flammable gases generated by heated vegetation, in particular the volatile organic compounds (VOC) common to Mediterranean plants, may, under certain topographic and wind conditions, accumulate in locations where, after the arrival of the ignition source, they rapidly burst into flames as explosions. Hence, there is a need for the development of a system that can monitor the development of these compounds. In this work, a sensor's array is proposed as a method for monitoring the amount of eucalyptol and α-pinene, the major VOC compounds of the Eucalyptus and Pine trees. The detection of the target compounds was assessed using the impedance spectroscopy response of thin films. Combinations of layers of polyelectrolytes, such as poly(allylamine hydrochloride) (PAH), polyethyleneimine (PEI), poly(sodium 4-sytrenesulfonate) (PSS) graphene oxide (GO), and non/functionalized multiwall nanotubes (MWCNT-COOH or MWCNT), namely, PAH/GO, PEI/PSS, PEI/GO, PAH/MWCNT, PAH/MWCNT-COOH, films, and TiO2 and ZnO sputtered films, were deposited onto ceramic supports coated with gold interdigitated electrodes. The results showed that concentrations of the target VOCs, within the range of 68 to 999 ppmv, can be easily distinguished by analyzing the impedance spectra, particularly in the case of the ZnO- and PAH/GO-film-based sensors, which showed the best results in the detection of the target compounds. Through principal component analysis (PCA), the best set of features attained for the ZnO and PAH/GO based sensor devices revealed a linear trend of the PCA's first principal component with the concentration within the range 109 and 807 ppmv. Thus, the values of sensitivity to eucalyptol and α-pinene concentrations, which were (2.2 ± 0.3) × 10-4 and (5.0 ± 0.7) × 10-5 per decade, respectively, as well as resolutions of 118 and 136 ppbv, respectively, were identified.publishersversionpublishe