CONSIDERATIONS REGARDING THE DEVELOPMENT OF NEW EQUIPMENT USED FOR HEMP HARVESTING

The important potential of cultivating hemp for fiber and cannabidiol extraction for medicinal use, makes this plant return to the attention of agronomists and medical researchers. Another strength of this plant is the potential of produced fibers to contribute to the decrease in the use of plastic in the near future, helping to reduce dependence on fossil fuels. In addition, hemp could be a more economically attractive alternative for ethanol generation or even for the production of high-strength construction materials. The paper aims to present several technologies used for hemp harvesting

Classification of autism spectrum disorder using supervised learning of brain connectivity measures extracted from synchrostates

This is the author accepted manuscript. The final version is available from IOP Publishing via the DOI in this record.OBJECTIVE: The paper investigates the presence of autism using the functional brain connectivity measures derived from electro-encephalogram (EEG) of children during face perception tasks. APPROACH: Phase synchronized patterns from 128-channel EEG signals are obtained for typical children and children with autism spectrum disorder (ASD). The phase synchronized states or synchrostates temporally switch amongst themselves as an underlying process for the completion of a particular cognitive task. We used 12 subjects in each group (ASD and typical) for analyzing their EEG while processing fearful, happy and neutral faces. The minimal and maximally occurring synchrostates for each subject are chosen for extraction of brain connectivity features, which are used for classification between these two groups of subjects. Among different supervised learning techniques, we here explored the discriminant analysis and support vector machine both with polynomial kernels for the classification task. MAIN RESULTS: The leave one out cross-validation of the classification algorithm gives 94.7% accuracy as the best performance with corresponding sensitivity and specificity values as 85.7% and 100% respectively. SIGNIFICANCE: The proposed method gives high classification accuracies and outperforms other contemporary research results. The effectiveness of the proposed method for classification of autistic and typical children suggests the possibility of using it on a larger population to validate it for clinical practice.The work presented in this paper was supported by FP7 EU funded MICHELANGELO project, Grant Agreement #288241. URL: www.michelangelo-project.eu/

Prediction of Synchrostate Transitions in EEG Signals Using Markov Chain Models

This is the author accepted manuscript. The final version is available from IEEE via the DOI in this record.This paper proposes a stochastic model using the concept of Markov chains for the inter-state transitions of the millisecond order quasi-stable phase synchronized patterns or synchrostates, found in multi-channel Electroencephalogram (EEG) signals. First and second order transition probability matrices are estimated for Markov chain modelling from 100 trials of 128-channel EEG signals during two different face perception tasks. Prediction accuracies with such finite Markov chain models for synchrostate transition are also compared, under a data-partitioning based cross-validation scheme.The work presented in this paper was supported by FP7 EU funded MICHELANGELO project, Grant Agreement #288241

CONSTRUCTION TYPES OF TECHNICAL EQUIPMENT FOR DOSING, WEIGHING, PACKAGING AND PROCEDURES USED IN MILLING UNITS

The paper presents several types of technical equipment for dosing, weighing, packaging and the procedures used in the milling units. The weighing systems take into account several important criteria for their design, namely: how the weight or mass of the load is offset and how the result is transferred

CONSIDERATIONS ON ENERGETIC CROPS POTENTIAL

In order to breathe fresh and clean air, nature and terrestrial atmosphere should be preserved and protected. Carbon emissions represent one of the main enemies of air quality. Recently, carbon emissions have surpassed all the predictions because the excessive industrialization, becoming the determining factor for global warming. A viable alternative to carbon emissions reduction is the utilization of energy sources that can diminish the noxious substances emissions up to zero. This can be done by using the power of wind, sun, water, energy plants, etc. Among the energetic potential plants, the biomass is obtained- a form of renewable energy which final product is biofuel

Dual-5α-Reductase Inhibition Promotes Hepatic Lipid Accumulation in Man

Context: 5α-Reductase 1 and 2 (SRD5A1, SRD5A2) inactivate cortisol to 5α-dihydrocortisol in addition to their role in the generation of DHT. Dutasteride (dual SRD5A1 and SRD5A2 inhibitor) and finasteride (selective SRD5A2 inhibitor) are commonly prescribed, but their potential metabolic effects have only recently been identified. Objective: Our objective was to provide a detailed assessment of the metabolic effects of SRD5A inhibition and in particular the impact on hepatic lipid metabolism. Design: We conducted a randomized study in 12 healthy male volunteers with detailed metabolic phenotyping performed before and after a 3-week treatment with finasteride (5 mg od) or dutasteride (0.5 mg od). Hepatic magnetic resonance spectroscopy (MRS) and two-step hyperinsulinemic euglycemic clamps incorporating stable isotopes with concomitant adipose tissue microdialysis were used to evaluate carbohydrate and lipid flux. Analysis of the serum metabolome was performed using ultra-HPLC-mass spectrometry. Setting: The study was performed in the Wellcome Trust Clinical Research Facility, Queen Elizabeth Hospital, Birmingham, United Kingdom. Main Outcome Measure: Incorporation of hepatic lipid was measured with MRS. Results: Dutasteride, not finasteride, increased hepatic insulin resistance. Intrahepatic lipid increased on MRS after dutasteride treatment and was associated with increased rates of de novo lipogenesis. Adipose tissue lipid mobilization was decreased by dutasteride. Analysis of the serum metabolome demonstrated that in the fasted state, dutasteride had a significant effect on lipid metabolism. Conclusions: Dual-SRD5A inhibition with dutasteride is associated with increased intrahepatic lipid accumulation. - See more at: http://press.endocrine.org/doi/10.1210/jc.2015-2928#sthash.KmmY91Iw.dpu

Susceptibility to fatty acid-induced β-cell dysfunction is enhanced in prediabetic diabetes-prone biobreeding rats: A potential link between β-cell lipotoxicity and islet inflammation

β-Cell lipotoxicity is thought to play an important role in the development of type 2 diabetes. However, no study has examined its role in type 1 diabetes, which could be clinically relevant for slow-onset type 1 diabetes. Reports of enhanced cytokine toxicity in fat-laden islets are consistent with the hypothesis that lipid and cytokine toxicity maybe synergistic. Thus, β-cell lipotoxicity could be enhanced in models of autoimmune diabetes. To determine this, we examined the effects of prolonged free fatty acids elevation on β-cell secretory function in the prediabetic diabetes-prone BioBreeding (dp-BB) rat, its diabetes-resistant BioBreeding (dr-BB) control, and normal Wistar-Furth (WF) rats. Rats received a 48-h iv infusion of saline or Intralipid plus heparin (IH) (to elevate free fatty acid levels ∼2-fold) followed by hyperglycemic clamp or islet secretion studies ex vivo. IH significantly decreased β-cell function, assessed both by the disposition index (insulin secretion corrected for IH-induced insulin resistance) and in isolated islets, in dp-BB, but not in dr-BB or WF, rats, and the effect of IH was inhibited by the antioxidant N-acetylcysteine. Furthermore, IH significantly increased islet cytokine mRNA and plasma cytokine levels (monocyte chemoattractant protein-1 and IL-10) in dp-BB, but not in dr-BB or WF, rats. All dp-BB rats had mononuclear infiltration of islets, which was absent in dr-BB and WF rats. In conclusion, the presence of insulitis was permissive for IH-induced β-cell dysfunction in the BB rat, which suggests a link between β-cell lipotoxicity and islet inflammation. Copyright © 2013 by The Endocrine Society

ASPECTS REGARDING THE CULTIVATION OF TOPINAMBOUR

Jerusalem artichoke (Helianthus tuberosusL.) is a perennial plant whose tubers containinulin,which can be used as raw material for healthy products, sweeteners, bioethanol and animal feed. The objective of this paper is o present some consideration about this very important plant for agriculture, medicine, food and health

EQUIPMENT FOR EXTRACTING AND PLANTING EARTH BALE ROOT PLANTS

Trees are one of the biggest  organisms living on the planet and their role is extremely important, namely that to maintain the purity of air we breathe, improve water quality, prevent soil erosion, reduce noise level, ensure food, construction materials and eventually people comfort. Plantation and transplantation of trees by means of specialized equipment  in comparison with human force leads to an increased planting speed and higher yield, economically speaking. This paper is designed to present different constructive variants, at world level, of equipment for extracting and planting trees with earth bale at their roots, necessary for afforestation, landscape design, tree nurseries

A search for periodic and quasi-periodic photometric behavior in the cataclysmic variable TT arietis

Observations of TT Ari obtained at 11 observatories (campaign TT Ari-94) during 258 hr were carried out to study optical variability on timescales from minutes to weeks. The best-fit primary photometric period determined from 16 nights of data obtained at the Dushak-Eregdag station of the Odessa State University is P = 0d.133160 ± 0d.000004 with a mean amplitude of 0.0513 ± 0.0008 mag. This new primary photometric period is larger than that obtained during the TT Ari-88 campaign and is well outside the range of estimates published since 1961. Contrary to previous findings, the "5-7 hr" secondary photometric period is not seen. Our observations do show evidence for periods of 2d.916 and 0d.3040 with amplitudes of 43 and 25 mmag, respectively. The beat period between the spectroscopic and photometric periods is not seen. No coherent oscillations in the range f = 10-2500 cycles day-1 are found. The highest peaks in the power spectrum cover the wide range of 24-139 cycles day-1. In the mean periodogram, the highest peak corresponds to 21 and 30 minutes for the largest sets of observations, i.e., those obtained at Odessa and Krakow Universities, respectively. In the instrumental B system, variations with an amplitude exceeding 0.011 mag occur 8 times (from 33 runs) at 24 minutes. We conclude that quasi-periodic variations occur at a few preferred timescales rather than at a relatively stable period with a secular decrease. In the frequency range 90-900 cycles day-1, the power spectrum obeys a power law with a slope ranging from γ = 1.3 to 2.6 for different runs