Development of High Precision Timing Counter Based on Plastic Scintillator with SiPM Readout

High-time-resolution counters based on plastic scintillator with silicon photomultiplier (SiPM) readout have been developed for applications to high energy physics experiments for which relatively large-sized counters are required. We have studied counter sizes up to $120\times40\times5$ mm^3 with series connection of multiple SiPMs to increase the sensitive area and thus achieve better time resolution. A readout scheme with analog shaping and digital waveform analysis is optimized to achieve the highest time resolution. The timing performance is measured using electrons from a Sr-90 radioactive source, comparing different scintillators, counter dimensions, and types of near-ultraviolet sensitive SiPMs. As a result, a resolution of $\sigma =42 \pm 2$ ps at 1 MeV energy deposition is obtained for counter size $60\times 30 \times 5$ mm^3 with three SiPMs ($3\times3$ mm^2 each) at each end of the scintillator. The time resolution improves with the number of photons detected by the SiPMs. The SiPMs from Hamamatsu Photonics give the best time resolution because of their high photon detection efficiency in the near-ultraviolet region. Further improvement is possible by increasing the number of SiPMs attached to the scintillator.Comment: 11 pages, 17 figures, accepted by IEEE Trans. Nucl. Sc

Effective and convenient treatment of Xultophy with lower doses for elderly diabetic patient

The case is an 82-year-old female patient with Type 2 Diabetes Mellitus (T2DM) for 22 years. She developed right empyema in early January, 2021 and was treated by antibiotics and CT-guided drainage. After improving the status, she was transferred to Hayashi hospital, Tokushima, Japan. Treatment for T2DM was initially multiple daily insulin injection (MDI), but it could not continue because of injection several times a day by the family. Then, Xultophy was started once a day, which brought satisfactory glucose variability with lower doses. Consequently, Xultophy would be effective and useful agent from bio-psycho-social points of view

Pixelated positron timing counter with SiPM-readout scintillator for MEG II experiment

In this paper, we introduce the positron timing counter (TC) for the MEG II experiment as an application of Silicon PhotoMultipliers (SiPM) to high-resolution timing measurement. MEG II will search for the μ → eγ decay and needs a precise measurement of the positron timing. The TC is segmented in 512 counters, composed of a scintillator plate readout by SiPMs, to obtain multiple hit positron timing simultaneously such to achieve an excellent overall timing resolution of ∼30 ps. We performed single counter R&D to optimize the choice of the SiPM manufacturer, the number of the SiPMs, and their connection. To obtain the best resolution, we decided to employ AdvanSiD SiPMs, six of which are attached at both ends connected in series. Moreover we carried out beam tests with 8-9 counters prototypes, where we proved that positron multiple hits improve the resolution according to expectation. The desgin phase of the TC is almost finished and is under construction