32 research outputs found
Preparation And Evaluation Of Mangrove Tannins-Based Adsorbent For The Removal Of Heavy Metal Ions From Aqueous Solution [QD327. C559 2008 f rb].
Struktur oligomer poliflavonoid tanin bakau yang diekstrak daripada kulit bakau Rhizophora apiculata dan prestasi penjerap berasaskan tanin (TBA) terhadap penjerapan ion logam berat daripada larutan akueus telah dikaji.
The polyflavonoid oligomeric structures of mangrove tannins extracted from the barks of Rhizophora apiculata and performance of tannins-based adsorbent (TBA) on the adsorption of heavy metal ions from the aqueous solutions were explored
A Simple Approach to Distinguish Classic and Formaldehyde-Free Tannin Based Rigid Foams by ATR FT-IR
Tannin based rigid foams (TBRFs) have been produced with formaldehyde since 1994. Only recently several methods have been
developed in order to produce these foams without using formaldehyde. TBRFs with and without formaldehyde are visually
indistinguishable; therefore a method for determining the differences between these foams had to be found. The attenuated total
reflectance infrared spectroscopy (ATR FT-IR) investigation of the TBRFs presented in this paper allowed discrimination between
the formaldehyde-containing (classic) and formaldehyde-free TBRFs.Thespectra of the formaldehyde-free TBRFs, indeed, present
decreased band intensity related to the C–O stretching vibration of (i) the methylol groups and (ii) the furanic rings. This evidence
served to prove the chemical difference between the two TBRFs and explained the slightly higher mechanical properties measured
for the classic TBRFs
4-Hydroxy-3-[(4-hydroxy-6-methyl-2-oxo-3,6-dihydro-2H-pyran-3-yl)(3-thienyl)methyl]-6-methyl-3,6-dihydro-2H-pyran-2-one
The asymmetric unit of the title compound, C17H14O6S, contains four crystallographically independent molecules in which the pyranone units are essentially planar, with maximum deviations of 0.016 (2), 0.019 (2), 0.025 (2), 0.014 (2), 0.020 (2), 0.010 (2), 0.003 (2) and 0.012 (2) Å. One of the thiophene rings is disordered over two positions, with an occupancy ratio of 0.739 (4):0.261 (4). The dihedral angles between the two pyranone rings in the independent molecules are 59.42 (8), 48.67 (8), 60.62 (9) and 51.60 (8)°. In the crystal, molecules are linked through intermolecular O—H⋯O and C—H⋯O hydrogen bonds, forming a three-dimensional network
3-[(E)-3-(2,4-Dichlorophenyl)prop-2-enoyl]-4-hydroxy-2H-chromen-2-one
In the title compound, C18H10Cl2O4, the chromen-2-one ring system is almost planar [maximum deviation = 0.028 (1) Å] and is inclined at an angle of 16.35 (4)° with respect to the benzene ring. The C=C bond has an E configuration. The molecular conformation is stabilized by an almost symmetric intramolecular O⋯H⋯O hydrogen bond and a C—H⋯O interaction, both of which form S(6) ring motifs. In the crystal structure, molecules are linked into sheets lying parallel to (100) via intermolecular C—H⋯O hydrogen bonds. The crystal packing is further consolidated by π–π stacking interactions [centroid-to-centroid separation = 3.6615 (6) Å]
3-[5-(2,4-Dichlorophenyl)-1-phenyl-4,5-dihydro-1H-pyrazol-3-yl]-4-hydroxy-2H-chromen-2-one
In the title compound, C24H16Cl2N2O3, the chromene ring system is almost planar, with a maximum deviation of 0.042 (1) Å. It makes dihedral angles of 3.72 (6), 73.37 (5) and 12.00 (5)° with the dihydropyrazole, benzene and phenyl rings, respectively. An intramolecular O—H⋯N hydrogen bond forms an S(6) ring motif. In the crystal, molecules are linked via C—H⋯O interactions, forming an infinite chain along the a axis. The crystal packing is further stabilized by a π–π stacking interaction [centroid–centroid distance = 3.5471 (7) Å] and a Cl⋯Cl short contact [Cl⋯Cl = 3.214 (1) Å]
3-Methyl-4-[(E)-3-thienylmethylideneamino]-1H-1,2,4-triazole-5(4H)-thione
The asymmetric unit of the title compound, C8H8N4S2, contains two crystallographically independent molecules. The thiophene ring of one molecule is disordered over two positions with refined site occupancies of 0.6375 (19) and 0.3625 (19). One molecule is almost planar and the other one is twisted, the dihedral angles between the thiophene and triazole rings being 7.28 (7) and 48.9 (2)° [48.5 (4)° for the minor component], respectively. An intramolecular C—H⋯S hydrogen bond stabilizes the molecular conformation of the planar molecule. In the crystal, the two molecules are interconnected by N—H⋯S hydrogen bonds into dimers, which are further consolidated into chains along the b axis by C—H⋯N hydrogen bonds. Weak C–H⋯π and π–π interactions [centroid–centroid distance = 3.5149 (7) Å] are also observed
4-Hydroxy-3-[(4-hydroxy-6,7-dimethyl-2-oxo-2H-chromen-3-yl)(4-oxo-4H-chromen-3-yl)methyl]-6,7-dimethyl-2H-chromen-2-one
In the title compound, C32H24O8, the molecular structure is disordered over two positions with refined site occupancies of 0.8746 (10) and 0.1254 (10). The mean plane of the three chromeno rings make dihedral angles with each other of 65.12 (4), 62.91 (4) and 59.70 (4)° in the major occupancy component and 59.1 (3), 66.1 (3) and 58.8 (3)° in the minor component. Intramolecular O—H⋯O hydrogen bonds stabilize the molecular structure and the crystal structure is stabilized by weak C–H⋯π and π–π interactions [centroid–centroid distances 3.496 (6)–3.672 (7) Å]
9-(7-Fluoro-4-oxo-4H-chromen-3-yl)-3,3,6,6-tetramethyl-2,3,4,5,6,7,8,9-octahydro-1H-xanthene-1,8-dione
In the title compound, C26H25FO5, the terminal cyclohexane rings of the xanthene ring system adopt half-boat conformations. The 4H-chromene ring make a dihedral angle of 87.94 (5)° with the xanthene ring system and its carbonyl O atom lies above the xanthene O atom. In the crystal, molecules are linked into ribbons propagating along the a-axis direction by C—H⋯O hydrogen bonds. Aromatic π–π stacking interactions [centroid–centroid distance = 3.7367 (12) Å] also occur
Overview of neurological mechanism of pain profile used for animal “pain-like” behavioral study with proposed analgesic pathways
Pain is the most common sensation installed in us naturally which plays a vital role in defending us against severe harm. This neurological mechanism pathway has been one of the most complex and comprehensive topics but there has never been an elaborate justification of the types of analgesics that used to reduce the pain sensation through which specific pathways. Of course, there have been some answers to curbing of pain which is a lifesaver in numerous situations—chronic and acute pain conditions alike. This has been explored by scientists using pain-like behavioral study methodologies in non-anesthetized animals since decades ago to characterize the analgesic profile such as centrally or peripherally acting drugs and allowing for the development of analgesics. However, widely the methodology is being practiced such as the tail flick/Hargreaves test and Von Frey/Randall–Selitto tests which are stimulus-evoked nociception studies, and there has rarely been a complete review of all these methodologies, their benefits and its downside coupled with the mechanism of the action that is involved. Thus, this review solely focused on the complete protocol that is being adapted in each behavioral study methods induced by different phlogogenic agents, the different assessment methods used for phasic, tonic and inflammatory pain studies and the proposed mechanism of action underlying each behavioral study methodology for analgesic drug profiling. It is our belief that this review could significantly provide a concise idea and improve our scientists’ understanding towards pain management in future research