The influence of nitrogen and phosphorus on the growth of a diatom Skeletonema costatum (Greville) Cleve

Nitrogen and phosphorus requirements of a chain-forming diatom, Skeletonema costatum (Greville) Cleve, collected from Yatsushiro Sea, Japan, were investigated in a laboratory culture experiment. Sodium nitrate and sodium glycerophosphate were used as nitrogen and phosphorus sources, respectively. Cultures were grown in modified Provasoli's ASP2NTA medium (Provasoli et al. 1957) at 25±1°C, light intensity 60 µE mˉ² secˉ¹ and photoperiod 12:12-h, L:D cycle. Optimum growth was observed at nitrate concentrations of 3-10 mglˉ¹ and phosphate concentrations of 1.5-15 mglˉ¹. Adequate growth was also found at the nitrate concentration of up to as high as 300 mglˉ¹. Significantly poorer growth was found at lower nitrate (15 mglˉ¹) concentrations. From the present study, it is concluded that S. costatum can grow well at wide ranges of nitrate concentrations but is sensitive to higher phosphate concentrations

Physiological observations on a diatom Skeletonema costatum (Greville) Cleve

A chain-forming diatom Skeletonema costatum (Greville) Cleve collected from Yatsushiro Sea, Japan was cultured to determine the optimum level of some physico-chemical factors for their growth under laboratory conditions. Filtered and sterilized aged sea water enriched by adding nutrient solution (Provasoli 1968) was used as the culture medium. The plankton could tolerate a wide range of salinities (3-55 ppt). Optimum growth was observed at salinities of 20-35 ppt, temperatures of 20-25°C, light intensities of 80-120µE mˉ² secˉ¹ and pH between 7.5 and 8.0. Growth did not occur at salinities below 3 ppt and at temperatures above 30°C. From the present study, it is concluded that S. costatum was extremely euryhaline and tolerable to very low salinities

XQR-30: Black Hole Masses and Accretion Rates of 42 z>6 Quasars

We present bolometric luminosities, black hole masses and Eddington ratios for 42 luminous quasars at z>6 using high signal-to-noise ratio VLT/X-Shooter spectra, acquired in the enlarged ESO Large Programme XQR-30. In particular, we derive bolometric luminosities from the rest-frame 3000 A, luminosities using a bolometric correction from the literature, and the black hole masses by modelling the spectral regions around the CIV 1549A and the MgII 2798A emission lines, with scaling relations calibrated in the local universe. We find that the black hole masses derived from both emission lines are in the same range, and the scatter of the measurements agrees with expectations from the scaling relations. The MgII-derived masses are between ~(0.8-12) x 10^9 Msun, and the derived Eddington ratios are within ~0.13-1.73, with a mean (median) of 0.84 (0.72). By comparing the total sample of quasars at z>5.8, from this work and from the literature, to a bolometric luminosity distribution-matched sample at z~1.5, we find that quasars at high redshift host slightly less massive black holes which accrete slightly more rapidly than at lower-z, with a difference in the mean Eddington ratios of the two samples of ~0.27, in agreement with recent literature work.Comment: 9 pages; 5 figures; accepted for publication in A&

The Hyper Suprime-Cam SSP Survey: Overview and Survey Design

Hyper Suprime-Cam (HSC) is a wide-field imaging camera on the prime focus of the 8.2m Subaru telescope on the summit of Maunakea in Hawaii. A team of scientists from Japan, Taiwan and Princeton University is using HSC to carry out a 300-night multi-band imaging survey of the high-latitude sky. The survey includes three layers: the Wide layer will cover 1400 deg$^2$ in five broad bands ($grizy$), with a $5\,\sigma$ point-source depth of $r \approx 26$. The Deep layer covers a total of 26~deg$^2$ in four fields, going roughly a magnitude fainter, while the UltraDeep layer goes almost a magnitude fainter still in two pointings of HSC (a total of 3.5 deg$^2$). Here we describe the instrument, the science goals of the survey, and the survey strategy and data processing. This paper serves as an introduction to a special issue of the Publications of the Astronomical Society of Japan, which includes a large number of technical and scientific papers describing results from the early phases of this survey.Comment: 14 pages, 7 figures, 5 tables. Corrected for a typo in the coordinates of HSC-Wide spring equatorial field in Table

X-ray emission from a rapidly accreting narrow-line Seyfert 1 galaxy at z = 6.56

The space density of X-ray-luminous, blindly selected active galactic nuclei (AGN) traces the population of rapidly accreting super-massive black holes through cosmic time. It is encoded in the X-ray luminosity function, whose bright end remains poorly constrained in the first billion years after the Big Bang as X-ray surveys have thus far lacked the required cosmological volume. With the eROSITA Final Equatorial-Depth Survey (eFEDS), the largest contiguous and homogeneous X-ray survey to date, X-ray AGN population studies can now be extended to new regions of the luminosity-redshift space (L2-10 keV > 1045 erg s-1 and z > 6). Aims. The current study aims at identifying luminous quasars at z > 5:7 among X-ray-selected sources in the eFEDS field in order to place a lower limit on black hole accretion well into the epoch of re-ionisation. A secondary goal is the characterisation of the physical properties of these extreme coronal emitters at high redshifts. Methods. Cross-matching eFEDS catalogue sources to optical counterparts from the DESI Legacy Imaging Surveys, we confirm the low significance detection with eROSITA of a previously known, optically faint z = 6:56 quasar from the Subaru High-z Exploration of Low-luminosity Quasars (SHELLQs) survey. We obtained a pointed follow-up observation of the source with the Chandra X-ray telescope in order to confirm the low-significance eROSITA detection. Using new near-infrared spectroscopy, we derived the physical properties of the super-massive black hole. Finally, we used this detection to infer a lower limit on the black hole accretion density rate at z > 6. Results. The Chandra observation confirms the eFEDS source as the most distant blind X-ray detection to date. The derived X-ray luminosity is high with respect to the rest-frame optical emission of the quasar.With a narrow Mgii line, low derived black hole mass, and high Eddington ratio, as well as its steep photon index, the source shows properties that are similar to local narrow-line Seyfert 1 galaxies, which are thought to be powered by young super-massive black holes. In combination with a previous high-redshift quasar detection in the field, we show that quasars with L2-10 keV > 1045 erg s-1 dominate accretion onto super-massive black holes at z _ 6

Prospect of vasoactive intestinal peptide therapy for COPD/PAH and asthma: a review

There is mounting evidence that pulmonary arterial hypertension (PAH), asthma and chronic obstructive pulmonary disease (COPD) share important pathological features, including inflammation, smooth muscle contraction and remodeling. No existing drug provides the combined potential advantages of reducing vascular- and bronchial-constriction, and anti-inflammation. Vasoactive intestinal peptide (VIP) is widely expressed throughout the cardiopulmonary system and exerts a variety of biological actions, including potent vascular and airway dilatory actions, potent anti-inflammatory actions, improving blood circulation to the heart and lung, and modulation of airway secretions. VIP has emerged as a promising drug candidate for the treatment of cardiopulmonary disorders such as PAH, asthma, and COPD. Clinical application of VIP has been limited in the past for a number of reasons, including its short plasma half-life and difficulty in administration routes. The development of long-acting VIP analogues, in combination with appropriate drug delivery systems, may provide clinically useful agents for the treatment of PAH, asthma, and COPD. This article reviews the physiological significance of VIP in cardiopulmonary system and the therapeutic potential of VIP-based agents in the treatment of pulmonary diseases