Are the single-step resection and primary anastomosis suitable for obstructıve colorectal patients in older cases?

Aim To investigate the efficacy and safety of the single-step surgery in elderly patients with obstructive colorectal cancer. Methods All patients who underwent single-step surgery and primary anastomosis for obstructive colorectal cancer in the period between January 2012 December 2017 were evaluated in this study. The patients were divided into two groups: younger than 65 (Group Young) and older than 65 (Group Old). Demographic data, American Society of Anesthesiologists scores (ASA) scores, comorbidities, preoperative albumin levels, type of surgery, postoperative morbidity and mortality, pathological stages, and overall survival rates were investigated. Results A total of 89 patients were included: 49 (54%) were older than 65 (Group Old). In Group Old, the mean age was 75 (65-97), of which 28 (58.3%) were males. There were 41 patients younger than 65 (Group Young) with the mean age of 52.6 (41-64 years of age), of which 21 (51.2%) were males. There was no difference between groups according to albumin level. There was no statistical difference between two groups according to tumour localization, pathological stage and type of surgery, as well as according to surgical complications. The median overall survival rate was 11 months in both groups (0-66) (p=0.320). Conclusion Meticulous preparation of older patients (correction of anaemia, electrolyte levels and pH ) paves the road for successful surgeries, including single-step resection and primary anastomosis

Designation of Environmental Impacts and Damages of Turbojet Engine: A Case Study with GE-J85

Between the troposphere and stratosphere layers of the atmosphere is a critical zone for collecting emissions and negative effects on the Earth (ecological, humanity, and resources). Aircrafts are the main causes of the impacts in this layer. In this study, environmental effects (Damages, Specific Fuel Consumption Impact-SFCI and Thrust Environmental Impact-TEI) of different fueled (Jet-A and Liquid Hydrogen-H2) jet engines (a case study with GE-J85) are investigated. This comparison was made between 7000–10,000 m altitude and 0.7–1.0 Mach. The maximum damages were found to be 82.44 PDF∙m2∙yr (Potentially Disappeared Fraction from one m2 area during one year), 1.75 × 10−3 DALY (disability-adjusted life years), and 8100 MJ Surplus for Ecosystem Quality, Human Health and Resources, respectively, at Jet-A fueled aircraft, 1 Mach, and 7000 m altitude. Additionally, the maximum SFCI was calculated as 344.03 mPts/kg at H2-fueled, 0.7 Mach, and 10,000 m; the minimum TEI was calculated as 13.78 mPts/N at H2-fueled aircraft, 0.7 Mach, and 9000 m. The best environmental (low specific fuel consumption and thrust impacts) flight situations were found in this study at a high altitude and a low Mach number

Energy-Absorbing and Eco-Friendly Perspectives for Cork and WKSF Based Composites under Drop-Weight Impact Machine

Lightweight structures with high energy absorption capacity are in high demand for energy absorption applications in a variety of engineering fields, such as aerospace, automotive, and marine engineering. Anti-impact composites are made of energy-absorbing materials that are incorporated into structures to protect the occupant or sensitive components against strikes or falls. This study deals with an experimental investigation of multi-layer composites consisting of cork and warp-knitted spacer fabrics (WKSF) for anti-impact applications. Composites were designed and created with a laser cutting machine in eight different configurations. To measure the energy absorption of the manufactured composite samples, a low-velocity drop-tower machine was designed, and the maximum reaction force due to the strike of the impactor on the specimens was measured by a dynamometer located under the samples. Moreover, energy absorption and specific energy absorption capacities were calculated for each specimen. In the final part of this study, the Life Cycle Assessment (LCA) of the designed composites was calculated to understand the eco-friendly properties of the composites

Influence of atropine therapy on fenthion-induced pancreatitis

Objective. We searched the influence of dose and timing of atropine therapy in fenthion-induced pancreatitis model. Methods. All rats were intoxicated with fenthion except the control group. Two milligrams of atropine was administered for 24 hours in a high dose atropine group while a low dose atropine group received 100 micrograms of atropine for 24 hours. One group received 2 milligrams of atropine in the first four hours of intoxication while the other group received 2 milligrams of atropine in the last four hours before sacrifice. All rats were sacrificed 24 hours after intoxication. Pseudo-cholinesterase and lipase concentrations and histopathological markers of pancreatitis were studied. Results. None of the models in this study completely prevented pancreatitis, however high dose atropine that is administered for 24 hours or the first four hours after intoxication prevented severe pancreatitis. Conclusion. Atropine administration influence on fenthion-induced pancreatitis should be studied for other organophosphates in animals and humans

Sustainability analyses of photovoltaic electrolysis and magnetic heat engine coupled novel system used for hydrogen production and electricity generation

In this study, energy and exergy based approaches, supported sustainability/ analyses, are applied to the photovoltaic (PV) electrolysis and magnetic heat engine, coupled novel system used for hydrogen production and electricity generation. The results point out that the magnetic field does not only improve the hydrogen production, but also low-temperature heat can be harvested by magnetic heat engine, and relatively more efficient electricity can be generated, in comparison to other harvesters. Magnetic heat engine reaches its maximum power output at 7.6 T and it is 5.53 W at this point. Energy and exergy efficiencies of the considered system are around 8% at 7.6 T, besides, it is assumed sustainable, at this value. Although the lost power is relatively higher, it can be tolerable because of unconsumable nature of the solar energy. In addition, it shows that most of energy input cannot be converted to electricity because of their ineffectiveness

The role of carnitine in preventing renal damage developed as a result of infrarenal aortic ischemia-reperfusion

Background: This study was designed to use carnitine for preventing deposition of end products of lipid peroxidation in rat models in the prevention of ischemia-reperfusion (IR) damage frequently seen following operations of infrarenal abdominal aorta (AA). Methods: Forty male rats of Sprague-Dawley type were evenly (n=8) randomized to five groups: sham laparotomy (SHAM), carnitine control (CC), aortic IR (AIR), AIR + low-dose carnitine (AIR+LDC), and AIR + high-dose carnitine (AIR+HDC). Results: Compared to other groups, serum creatinine levels of AIR group were significantly higher. Also tissue malondialdehyde (MDA) levels of AIR group were significantly higher compared to SHAM, CC, and AIR+HDC groups. In histopathological examination, although tubular necrosis atrophy and tubular degeneration observed in AIR group showed regression with low-dose carnitine, tubular necrosis atrophy, tubular degeneration, glomerular damage, and vascular congestion thrombosis decreased with high-dose carnitine. Total score of histological damage was significantly higher in AIR, AIR+LDC, and AIR+HDC groups compared to SHAM and CC groups. Moreover, total score of histological damage was significantly lower in AIR+HDC group than AIR+LDC group. Conclusions: In this study, we showed carnitine can partially prevent renal damage in infrarenal AIR models of rats. This result may open new prospects to us in the prevention of renal IR damage during surgery of aorta. © 2011 Informa Healthcare USA, Inc