N-acetylcysteine – antioxidant action and use in the small animal clinic

A N-acetilcisteína, durante muito tempo, teve seu uso restrito à ação mucolítica e expectorante e ao tratamento da intoxicação por paracetamol. Com o advento de estudos acerca de radicais livres, os antioxidantes ganharam destaque e, dentre eles, a N-acetilcisteína. Esta revisão de literatura tem por objetivo realçar a atividade farmacológica desse aminoácido em afecções da rotina clínica de pequenos animais, bem como apresentar as novas perspectivas de utilização em seres humanos, que poderão embasar, futuramente, estudos semelhantes em cães e gatos.For a long time, N-acetylcysteine was only used as a mucolytic and expectorant agent and in the treatment of paracetamol intoxication.  With the advent of studies on free radicals, antioxidants are gaining prominence and the N-acetylcysteine is among them.  The objective of this article is to highlight the farmacological activity of this amino acid in affections in the small animal clinical routine, as well as to present new perspectives in its use in human, which could, in the future, form the base for similar studies in dogs and cats

N-acetilcisteína - ação antioxidante e utilização na clínica de pequenos animais

For a long time, N-acetylcysteine was only used as a mucolytic and as an expectorant agent in the treatment of paracetamol/ acetaminophen intoxication. With the advent of studies on free radicals, antioxidants are gaining prominence and the N-acetylcysteine is amongst them. The objective of this article is to emphazise the farmacological activity of this amino acid in affections in the small animal clinical routine, as well as to show new perspectives of its use in humans, which could, in the future, form the base for similar studies in dogs and cats

N-acetilcisteína - Ação antioxidante e utilização na clínica de pequenos animais

For a long time, N-acetylcysteine was only used as a mucolytic and as an expectorant agent in the treatment of paracetamol/ acetaminophen intoxication. With the advent of studies on free radicals, antioxidants are gaining prominence and the N-acetylcysteine is amongst them. The objective of this article is to emphazise the farmacological activity of this amino acid in affections in the small animal clinical routine, as well as to show new perspectives of its use in humans, which could, in the future, form the base for similar studies in dogs and cats