Large Area Crop Inventory Experiment (LACIE). The boundary pixel study in Kansas and North Dakota

The author has identified the following significant results. The statistical mapping approach to handling boundary pixels can be used as a standard for objectively comparing the cluster based technique, the maximum likelihood estimate based technique, and multicategory labeling

Large Area Crop Inventory Experiment (LACIE). Phase 3 direct wheat study of North Dakota

The author has identified the following significant results. The green number and brightness scatter plots, channel plots of radiance values, and visual study of the imagery indicate separability between barley and spring wheat/oats during the wheat mid-heading to mid-ripe stages. In the LACIE Phase 3 North Dakota data set, the separation time is more specifically the wheat soft dough stage. At this time, the barley is ripening, and is therefore, less green and brighter than the wheat. Only 4 of the 18 segments studied indicate separation of barley/other spring small grain, even though 11 of the segments have acquisitions covering the wheat soft dough stage. The remaining seven segments had less than 5 percent barley based on ground truth data

Hubungan Dukungan Suami Dan Dukungan Keluarga Dengan Pemberian Asi Eksklusif Pada Ibu Anggota Kelompok Pendukung Asi (Kp-asi)

Breast milk is the best investment for children\u27s health and intelligence of. Exclusive breastfeeding is influenced by health behavior factors, one of which is a driving factor including husband and family support that is necessary for mothers to breastfeed exclusively. The purpose of this study was to analyze the relationship between husband and family support with exclusive breastfeeding in breastfed mothers of KP-ASI members in Megaluh Jombang Public Health Center. This study is an observational analytic study with cross sectional design. Sample was breastfed mother who is participant of KP-ASI and had infants aged 6-12 months as much as 74 people selected using purposive sampling method. The data was collected through interview using a questionnaire. The result showed there was a correlation between family support and exclusive breastfeeding behavior (p = 0.011) but there was no correlation between husband support with exclusive breastfeeding behavior (p = 0.090). In conclusion, family support as reinforcing factor can motivate a mother to do exclusive breastfeeding. It is expected that all members of the family can provide support for mother to breastfeed exclusively and cadres can also invite mothers\u27 family members (parents, husband, siblings) to participate in the counseling (KP-ASI) activity and provide education regarding the importance of exclusive breastfeeding

SAX J1808.4-3658, an accreting millisecond pulsar shining in gamma rays?

We report the detection of a possible gamma-ray counterpart of the accreting millisecond pulsar SAX J1808.4-3658. The analysis of ~6 years of data from the Large Area Telescope on board the Fermi Gamma-ray Space Telescope (Fermi-LAT) within a region of 15deg radius around the position of the pulsar reveals a point gamma-ray source detected at a significance of ~6 sigma (Test Statistic TS = 32), with position compatible with that of SAX J1808.4-3658 within 95% Confidence Level. The energy flux in the energy range between 0.6 GeV and 10 GeV amounts to (2.1 +- 0.5) x 10-12 erg cm-2 s-1 and the spectrum is well-represented by a power-law function with photon index 2.1 +- 0.1. We searched for significant variation of the flux at the spin frequency of the pulsar and for orbital modulation, taking into account the trials due to the uncertainties in the position, the orbital motion of the pulsar and the intrinsic evolution of the pulsar spin. No significant deviation from a constant flux at any time scale was found, preventing a firm identification via time variability. Nonetheless, the association of the LAT source as the gamma-ray counterpart of SAX J1808.4-3658 would match the emission expected from the millisecond pulsar, if it switches on as a rotation-powered source during X-ray quiescence.Comment: 8 pages, 4 figures, accepted by MNRA

Consumer Demand for Environmental, Social, and Ethical Information in Fishery and Aquaculture Product Labels

Customers’ attention to sustainability labels in fishery and aquaculture products (FAPs) has been increasing in the last decades, and the industry has adapted to this growing interest by adopting fish ecolabels. However, there is a growing interest to widen the sustainability concept to include the social and ethical information of the fishery and aquaculture industry and to go further from the voluntary approach on the labeling of these aspects in FAPs. For this reason, using data from 2021 Eurobarometer and using machine learning techniques, we disentangle the characteristics of the FAP buyers that consider the importance of environmental impact, ethical, and social information appearing on FAP labeling. The results confirmed that most of the consumers who consider environmental, social, and ethical aspects when buying FAPs also think that this information should be labeled. In line with other works, young, educated, and environmentally aware consumers in high-income countries are more likely to request this information in the FAP label. One interesting finding of the study relates with the asymmetric impact of the variables and the important group of respondents who do not consider these aspects but also advocate to include them in the FAP label. The study outcomes can be beneficial for policymakers to design future public policies regarding FAP labeling, as well as to be taken into consideration in the marketing policies of fishery and aquaculture producers and retailers

Conservation of context-dependent splicing activity in distant Muscleblind homologs

The Muscleblind (MBL) protein family is a deeply conserved family of RNA binding proteins that regulate alternative splicing, alternative polyadenylation, RNA stability and RNA localization. Their inactivation due to sequestration by expanded CUG repeats causes symptoms in the neuromuscular disease myotonic dystrophy. MBL zinc fingers are the most highly conserved portion of these proteins, and directly interact with RNA. We identified putative MBL homologs in Ciona intestinalis and Trichoplax adhaerens, and investigated their ability, as well as that of MBL homologs from human/mouse, fly and worm, to regulate alternative splicing. We found that all homologs can regulate alternative splicing in mouse cells, with some regulating over 100 events. The cis-elements through which each homolog exerts its splicing activities are likely to be highly similar to mammalian Muscleblind-like proteins (MBNLs), as suggested by motif analyses and the ability of expanded CUG repeats to inactivate homolog-mediated splicing. While regulation of specific target exons by MBL/MBNL has not been broadly conserved across these species, genes enriched for MBL/MBNL binding sites in their introns may play roles in cell adhesion, ion transport and axon guidance, among other biological pathways, suggesting a specific, conserved role for these proteins across a broad range of metazoan species.National Institutes of Health (U.S.) (DP5 OD017865

An Intervention Delivered by App Instant Messaging to Increase Acceptability and Use of Effective Contraception Among Young Women in Bolivia: Protocol of a Randomized Controlled Trial.

BACKGROUND: Unintended pregnancy is associated with numerous poorer health outcomes for both women and their children. Fulfilling unmet need for contraception is essential in avoiding unintended pregnancies, yet millions of women in low- and middle-income countries continue to face obstacles in realizing their fertility desires. In Bolivia, family planning progress has improved in recent decades but lags behind other countries in the region. Unmet need for contraception among women aged 15 to 19 years is estimated to be 38%, with the adolescent fertility rate at 70 per 1000 women. Mobile phones are an established and popular mode in which to deliver health behavior support. The London School of Hygiene & Tropical Medicine and the Centro de Investigación, Educación y Servicios in Bolivia have partnered to develop and evaluate a contraceptive behavioral intervention for Bolivian young women delivered by mobile phone. The intervention was developed guided by behavioral science and consists of short instant messages sent through an app over 4 months. OBJECTIVE: The objective of this study is to evaluate the effect of the intervention on young women's use of and attitudes toward the most effective contraceptive methods. METHODS: We will allocate 1310 women aged 16 to 24 years with an unmet need for contraception in a 1:1 ratio to receive the intervention messages or the control messages about trial participation. The messages are sent through the Tú decides app, which contains standard family planning information. Coprimary outcomes are use and acceptability of at least one effective contraceptive method, both measured at 4 months. RESULTS: Recruitment commenced on March 1, 2017 and was completed on July 29, 2017. We estimate that the follow-up period will end in January 2018. CONCLUSIONS: This trial will evaluate the effect of the intervention on young women's use of and attitudes toward the (nonpermanent) effective contraception methods available in Bolivia. TRIAL REGISTRATION: ClinicalTrials.gov NCT02905526; https://clinicaltrials.gov/ct2/show/NCT02905526 (Archived by WebCite at http://www.webcitation.org/6vT0yIFfN)

Safetxt: a pilot randomised controlled trial of an intervention delivered by mobile phone to increase safer sex behaviours in young people.

OBJECTIVE: To test the procedures proposed for a main trial of a safer sex intervention for young people delivered by mobile phone text message ('safetxt'). DESIGN AND SETTING: Pilot randomised controlled trial. Participants were recruited through sexual health services in the UK. An independent online randomisation system allocated participants to receive the safetxt intervention or to receive the control text messages (monthly messages about participation in the study). Texting software delivered the messages in accordance with a predetermined schedule. PARTICIPANTS: Residents of England aged 16-24 who had received either a positive chlamydia test result or reported unsafe sex in the last year (defined as more than 1 partner and at least 1 occasion of sex without a condom). INTERVENTION: The safetxt intervention is designed to reduce sexually transmitted infection in young people by supporting them in using condoms, telling a partner about an infection and testing before unprotected sex with a new partner. Safetxt was developed drawing on: behavioural science; face-to-face interventions; the factors known to influence safer sex behaviours and the views of young people. OUTCOMES: The coprimary outcomes of the pilot trial were the recruitment rate and completeness of follow-up. RESULTS: We recruited 200 participants within our target of 3 months and we achieved 81% (162/200) follow-up response for the proposed primary outcome of the main trial, cumulative incidence of chlamydia at 12 months. CONCLUSIONS: Recruitment, randomisation, intervention delivery and follow-up were successful and a randomised controlled trial of the safetxt intervention is feasible. TRIAL REGISTRATION NUMBER: ISRCTN02304709; Results

KEGIATAN PENGABDIAN MASYARAKAT DI PULAU SAPARUA, MALUKU: PERSEPSI DAN PENGETAHUAN KADER TENTANG POS PEMBINAAN TERPADU PENYAKIT TIDAK MENULAR

Peningkatan kasus penyakit tidak menular (PTM) telah menjadi salah satu masalah kesehatan masyarakat di Indonesia. Salah satu upaya pengendalian PTM dibangun berdasarkan komitmen dan keterlibatan masyarakat adalah melalui Pos Pembinaan Terpadu (Posbindu) PTM. Pada kenyatannya, pelaksanaan Posbindu PTM di Indonesia, masih menghadapi berbagai masalah, termasuk di Provinsi Maluku. Oleh karena itu, Fakultas Kedokteran Universitas Pattimura melaksanakan kegiatan pengabdian kepada masyarakat, bekerja sama dengan kader kesehatan dari kelima Puskesmas di Pulau Saparua, Kabupaten Maluku Tengah, Provinsi Maluku melakukan kegiatan pelatihan kader dalam rangka meningkatkan pengetahuan dan keterampilan kader dalam memberikan pelayanan Posbindu PTM Dasar di wilayah kerjanya. Pelatihan kader dilaksanakan di Pulau Saparua pada tanggal 15 November 2019, dihadiri 26 kader dari lima Puskesmas di Pulau Saparua. Evaluasi kegiatan pelatihan ini terdiri dari: (1) Evalasi kuantitatif dan (2) Evaluasi kualitatif. Dari evaluasi evaluasi kuantitatif yang dilakukan, tampak peningkatan yang signifikan dalam pengetahuan kader tentang Posbindu PTM, yang ditunjukkan dengan perbedaan persentase jawaban benar sebelum dan setelah dilakukannya pelatihan (p<0.001). Dari evaluasi kualitatif berupa diskusi kelompok dengan para kader, terlihat bahwa kader sangat menyambut baik pelaksanaan Posbindu PTM walaupun ada beberapa kendala yang ditengarai dapat menjadi faktor penghambat, termasuk keterbatasan sumber daya manusia terutama kader, kurangnya dukungan dari lintas sektor, terbatasnya pendanaan serta kondisi geografis yang cukup luas dan sulit. Hambatan ini penting untuk diperhatikan para pemangkukebijakan sehingga Posbindu PTM di Pulau Saparua dapat terlaksana dengan baik

Hyperperfusion profiles after recanalization differentially associate with outcomes in a rat ischemic stroke model

Futile recanalization hampers prognoses of ischemic stroke after successful mechanical thrombectomy, hypothetically through post-recanalization perfusion deficits, onset-to-groin delays and sex effects. Clinically, acute multiparametric imaging studies remain challenging. We assessed possible relationships between these factors and disease outcome after experimental cerebral ischemia-reperfusion, using translational MRI, behavioral testing and multi-model inference analyses. Male and female rats (N = 60) were subjected to 45-/90-min filament-induced transient middle cerebral artery occlusion. Diffusion, T2- and perfusion-weighted MRI at occlusion, 0.5 h and four days after recanalization, enabled tracking of tissue fate, and relative regional cerebral blood flow (rrCBF) and -volume (rrCBV). Lesion areas were parcellated into core, salvageable tissue and delayed injury, verified by histology. Recanalization resulted in acute-to-subacute lesion volume reductions, most apparently in females (n = 19). Hyperacute normo-to-hyperperfusion in the post-ischemic lesion augmented towards day four, particularly in males (n = 23). Tissue suffering delayed injury contained higher ratios of hypoperfused voxels early after recanalization. Regressed against acute-to-subacute lesion volume change, increased rrCBF associated with lesion growth, but increased rrCBV with lesion reduction. Similar relationships were detected for behavioral outcome. Post-ischemic hyperperfusion may develop differentially in males and females, and can be beneficial or detrimental to disease outcome, depending on which perfusion parameter is used as explanatory variable.</p