Comparison of Data Mining Techniques for Predicting Compressive Strength of Environmentally Friendly Concrete

This material may be downloaded for personal use only. Any other use requires prior permission of the American Society of Civil Engineers. This material may be found at https://ascelibrary.org/doi/10.1061/%28ASCE%29CP.1943-5487.0000596 With its growing emphasis on sustainability, the construction industry is increasingly interested in environmentally friendly concrete produced by using alternative and/or recycled waste materials. However, the wide application of such concrete is hindered by the lack of understanding of the impacts of these materials on concrete properties. This research investigates and compares the performance of nine data mining models in predicting the compressive strength of a new type of concrete containing three alternative materials as fly ash, Haydite lightweight aggregate, and portland limestone cement. These models include three advanced predictive models (multilayer perceptron, support vector machines, and Gaussian processes regression), four regression tree models (M5P, REPTree, M5-Rules, and decision stump), and two ensemble methods (additive regression and bagging) with each of the seven individual models used as the base classifier

Hyperinsulinism-hyperammonaemia syndrome: novel mutations in the GLUD1 gene and genotype-phenotype correlations

Background: Activating mutations in the GLUD1 gene (which encodes for the intra-mitochondrial enzyme glutamate dehydrogenase, GDH) cause the hyperinsulinism–hyperammonaemia (HI/HA) syndrome. Patients present with HA and leucine-sensitive hypoglycaemia. GDH is regulated by another intra-mitochondrial enzyme sirtuin 4 (SIRT4). Sirt4 knockout mice demonstrate activation of GDH with increased amino acid-stimulated insulin secretion. Objectives: To study the genotype–phenotype correlations in patients with GLUD1 mutations. To report the phenotype and functional analysis of a novel mutation (P436L) in the GLUD1 gene associated with the absence of HA. Patients and methods: Twenty patients with HI from 16 families had mutational analysis of the GLUD1 gene in view of HA (n=19) or leucine sensitivity (n=1). Patients negative for a GLUD1 mutation had sequence analysis of the SIRT4 gene. Functional analysis of the novel P436L GLUD1 mutation was performed. Results: Heterozygous missense mutations were detected in 15 patients with HI/HA, 2 of which are novel (N410D and D451V). In addition, a patient with a normal serum ammonia concentration (21 µmol/l) was heterozygous for a novel missense mutation P436L. Functional analysis of this mutation confirms that it is associated with a loss of GTP inhibition. Seizure disorder was common (43%) in our cohort of patients with a GLUD1 mutation. No mutations in the SIRT4 gene were identified. Conclusion: Patients with HI due to mutations in the GLUD1 gene may have normal serum ammonia concentrations. Hence, GLUD1 mutational analysis may be indicated in patients with leucine sensitivity; even in the absence of HA. A high frequency of epilepsy (43%) was observed in our patients with GLUD1 mutations

The Minimum Shared Edges Problem on Grid-like Graphs

We study the NP-hard Minimum Shared Edges (MSE) problem on graphs: decide whether it is possible to route $p$ paths from a start vertex to a target vertex in a given graph while using at most $k$ edges more than once. We show that MSE can be decided on bounded (i.e. finite) grids in linear time when both dimensions are either small or large compared to the number $p$ of paths. On the contrary, we show that MSE remains NP-hard on subgraphs of bounded grids. Finally, we study MSE from a parametrised complexity point of view. It is known that MSE is fixed-parameter tractable with respect to the number $p$ of paths. We show that, under standard complexity-theoretical assumptions, the problem parametrised by the combined parameter $k$, $p$, maximum degree, diameter, and treewidth does not admit a polynomial-size problem kernel, even when restricted to planar graphs

Iron Status in Febrile Seizure: A Case-Control Study

ObjectiveData on the relationship between iron deficiency anemia and febrile convulsions are controversial. The aim of this study was to determine the association between iron deficiency anemia and febrile convulsions among children.Materials & MethodsThis case-control study was conducted during 2006-2007, on 90 children with febrile seizures (case) and 90 febrile children without seizures (control) referred to the Amirkola children hospital (a referral hospital in the north of Iran). Two groups were matched for age and sex. In all children hemoglobin (Hb) level, hematocrit (Hct), mean corpuscular volume (MCV), mean corpuscular hemoglobin (MCH) and plasma ferritin (PF) were determined and the data collected were analyzed statistically using the t-test.ResultsThe mean PF and TIBC levels were not significantly different in the febrile seizure compared to the reference group; neither were differences in Hb levels statistically significant between two groups. However MCV and MCH were significantly higher in the febrile seizure group (pConclusionPlasma ferritin levels were not significantly lower in children with febrile seizures in comparison with the children in control group. It seems that iron insufficiency does not play a role in pediatric febrile seizures.

Role of CD99 in adult patients with acute myeloid leukemia

Background: When it comes to acute myeloid leukemia (AML), the large proportion of patients usually have relapses. Acute myeloid leukemia, Lymphoblastic lymphoma/leukemia, as well as Ewing sarcoma all have high CD99 expression.Objective: The aim of the current work was to assess CD99 expression frequency in patients with AML, and also to evaluate its association with different clinical and laboratory data.Patients and Methods: This comprehensive study included a total of 40 AML patients and 20 matched healthy subjects, attending at Departments of Clinical Pathology and Medical Oncology, Faculty of Medicine, Zagazig University Hospitals. Clinical and laboratory data were correlated with CD99 expression frequency in patients with AML in order to examine its usefulness as a predictive and prognostic factor.Results: Examination of CD99 expression in AML patients revealed that 80% of patients are CD99 positive, while (20%) are negative.Conclusion: CD99 expression in acute myeloid leukemia patients is of good prognostic value

Structural, elastic, mechanical and thermodynamic properties of Terbium oxide: First-principles investigations

First-principles investigations of the Terbium oxide TbO are performed on structural, elastic, mechanical and thermodynamic properties. The investigations are accomplished by employing full potential augmented plane wave FP-LAPW method framed within density functional theory DFT as implemented in the WIEN2k package. The exchange-correlation energy functional, a part of the total energy functional, is treated through Perdew Burke Ernzerhof scheme of the Generalized Gradient Approximation PBEGGA. The calculations of the ground state structural parameters, like lattice constants a0, bulk moduli B and their pressure derivative B′ values, are done for the rock-salt RS, zinc-blende ZB, cesium chloride CsCl, wurtzite WZ and nickel arsenide NiAs polymorphs of the TbO compound. The elastic constants (C11, C12, C13, C33, and C44) and mechanical properties (Young's modulus Y, Shear modulus S, Poisson's ratio σ, Anisotropic ratio A and compressibility β), were also calculated to comprehend its potential for valuable applications. From our calculations, the RS phase of TbO compound was found strongest one mechanically amongst the studied cubic structures whereas from hexagonal phases, the NiAs type structure was found stronger than WZ phase of the TbO. To analyze the ductility of the different structures of the TbO, Pugh's rule (B/SH) and Cauchy pressure (C12–C44) approaches are used. It was found that ZB, CsCl and WZ type structures of the TbO were of ductile nature with the obvious dominance of the ionic bonding while RS and NiAs structures exhibited brittle nature with the covalent bonding dominance. Moreover, Debye temperature was calculated for both cubic and hexagonal structures of TbO in question by averaging the computed sound velocities

Behavior of expanded polystyrene (EPS) blocks under cyclic pavement foundation loading

This study introduces a mechanism for initial assessment and future development to improve understanding of expanded polystyrene (EPS) behavior as a super-lightweight material for road construction. Large scale cyclic plate load tests on model pavements were performed. The effect of several factors including thickness of soil, thickness of subsequent EPS layers and density of EPS on the surface deformations, resilient modulus (Mr) and interlayer pressure transfer were investigated. The results indicated that, compared to a covering soil layer of 300 mm, the rut depth on the loading surface reduced by 13.5% and 40.8% when the soil thickness was increased by 33% and 100%, respectively. With a constant soil thickness, increasing the thickness of an upper (denser) EPS layer with respect to a bottom (softer) EPS layer, from 200 mm to 600 mm, would only result in a 20% decrease in the peak settlements after loading. Resilient modulus of the system was found to be dependent on soil thickness. A designer can choose an appropriate resilient modulus assuming the soil-EPS composite acts as subgrade or subbase. In order to extend the results to a wider range of geofoams, soils and layer thicknesses, a simple stress analysis method was also trialed

An examination of the banking efficiency of the BRICS countries : a perspective derived from the oil price volatility

This study examines the influence of Oil Price Volatility on Banks efficiency within the BRICS countries (Brazil, Russia, India, China, and South Africa) noting the importance of the banking sector efficiency as a tool to ensure financial stability in the region. Being able to measure efficiency levels in banks determines how successful a bank is in managing its operations and achieving its goals. A sample data of 112 banks was selected using the Bank Scope database over the time interval 2003 to 2018 to inspect banking sector relative efficiency following a non-parametric methodology known as Data Envelopment Analysis (DEA). The paper applies a two-stage model to process the empirical results consisting in using the Data Envelopment Analysis (DEA) to identify the scores of banks efficiency at a first stage (Stage 1) and determining how volatility in Oil price has impact on these scores of efficiencies on a second stage (Stage 2). Findings of the study indicate that the Chinese banking system shows the highest efficiency (90%), followed by the South Africa (87%), followed by the Brazilian and Indian banking system with efficiency level of (77%), the Russian bank industry revealed the lowest efficient banking system with level of efficiency (50%)