HUBUNGAN SENSISTIVITAS PLASMODIUM FALCIPARUM TERHADAP KOMBINASI PIRIMETAMIN/SULFADOKSIN DAN KLOROKUIN SECARA IN VITRO

An in vitro sensitivity test was conducted to study the sensitivity of Plasmodium falciparum against chloroquine and pyrimethamine/sulphadoxine combination. The relationship between sensitivity of the parasite to the two drugs was also studied. A total of 72 patients from five localities were examined during 1984-1985. Test against chloroquine was conduc­ted according to WHO method, while against pyrimethamine/sulphadoxine combination, a modified method of Nguyen Dinh and Payne and Eastham and Rieckmann was used. The results showed that there is no relationship between the sensitivity of P. falciparum against pyrimethamine/ sulphadoxine combination and chloroquine. It can be concluded that in case of chloroquine resistant P. falciparum, pyrimethamine/sulphadoxine combination could be applied as an alternative chemotherapy

Studi Epidemiologi Fasciolopsis Buski Di Kabupaten Hulu Sungai Utara - Kalsel Tahun 2002-2003

Fasciolopsis buski is one of the biggest trematode parasite which can be infected the human being because the worm live in lumen intestine. Human can be infected because eat raw or unwell cooked water plants. In Indonesia, this worm diseases only found in some village in Hulu Sungai Utara district, with prevalence between 1,2-7,8%. The research design is a cross sectional with collecting epidemiology data, such as parasite examination on the reservoir (it suppose to buffalo swamp), the intermediate host (some species snails), water plants of parasite encystation (water lily, water chesnut, water cress). Result of the examination of stool, 7,8% (121/1.555 person) have positive egg of F. buski. The collecting result of epidemiology data for looking the water plants of metacercariae eocystations, the intermediate host of cercariae growth and host reservoir has been collected 206 specimens but can not find the water plants of encystations or the intermediate host