37 research outputs found

    Coronary Artery and Mitral Valve Surgery in Takayasu's Arteritis: A Case Report

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    Concomitant coronary artery disease and mitral valve disease are rare in Takayasu's Arteritis. Our patient had Takayasu's Arteritis diagnosed 9 years ago. She had an inferior myocardial infarction and double stent implantation 8 months ago. She was admitted to the hospital for chest pain, and 3 vessel diseases were diagnosed with significant mitral regurgitation due to anterior leaflet prolapse. In this report, we present perioperative management of our patient who underwent coronary artery bypass grafting and mitral valve replacement

    Novel pthalocyanines bearing 4-ferrocenylphenoxy substituents and their electrochemistry

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    Biyiklioglu, Zekeriya/0000-0001-5138-214XWOS: 000327939000040The synthesis, spectroscopic and electrochemical properties of the tetra-(4-ferrocenylphenoxy) substituted metal-free, zinc(II) and cobalt(II) phthalocyanines reported for the first time. Metal-free, zinc(II) and cobalt(II) phthalocyanines were synthesized from 4-(ferrocenylphenoxy)phthalonitrile 3 which was obtained from 4-ferrocenylphenol 1 and 4-nitrophthalonitrile 2. The compounds have been characterized by IR, UV-Vis, H-1 NMR, C-13 NMR, MALDI-TOF mass spectral data. The electrochemical properties of the phthalocyanines were also investigated by cyclic and square wave voltammetry techniques. Cyclic and square wave voltammetric studies show that phthalocyanines have reversible/quasi-reversible redox processes, which are the main requirement for the technological usage of these compounds. (C) 2013 Elsevier B. V. All rights reserved.Research Fund of Karadeniz Technical University (Trabzon-Turkey)Karadeniz Teknik University [8660]This study was supported by the Research Fund of Karadeniz Technical University, project no: 8660, (Trabzon-Turkey)

    A novel selective fluorescent chemosensor for Fe3+ ions based on phthalonitrile dimer: synthesis, analysis, and theoretical studies

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    PubMed: 33488226Phenyl-4,4-di(3,6-dibutoxyphthalonitrile) (3) was synthesized by the reaction of 1,4-phenylenebisboronic acid (1) and 4-bromo-3,6-dibutoxyphthalonitrile (2), using Suzuki cross-coupling reaction. The newly synthesized compound (3) was characterized by FT-IR, MALDI-MS, ESI-MS, H-1-NMR, C-13-NMR, and C-13-DEPT-135-NMR. The fluorescence property of phenyl-4,4-di(3,6-dibutoxyphthalonitrile) (3) towards various metal ions was investigated by fluorescence spectroscopy, and it was observed thatthe compound (3) displayed a significantly 'turn-off' response to Fe3+, which was referred to 1:2 complex formation between ligand (3) and Fe3+. The compound was also studied via density functional theory calculations revealing the interaction mechanism of the molecule with Fe3+ ions

    A useful cannulation strategy to facilitate re-warming during total arch replacement

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    "Distal-first" surgical technique with antegrade cerebral perfusion and early re-warming is a secure and comfortable method for aortic arch replacement. By using this technique, we can minimize total circulatory arrest and hypothermic periods. Cerebral morbidities can be reduced by antegrade cerebral perfusion which is achieved via both axillary cannulation and balloon-catheters. Distal organ, cerebral, and renal morbidities can be minimized by early femoral arterial perfusion and early re-warming that is re-started immediately after distal anastomosis is performed

    The reliability of estimated glomerular filtration rate in coronary artery bypass grafting

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    Background: In this study, we investigated the reliability of the estimated creatinine clearance and glomerular filtration rate in patients undergoing on-pump coronary artery bypass grafting

    The Reliability of the Use of Serum Neutrophil Gelatinase-Associated Lipocalin Levels in the Assessment of Renal Functions after Coronary Artery Bypass Grafting

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    Objective. Evaluation of perioperative renal function is very important for early diagnosis and treatment of acute kidney injury after coronary artery bypass grafting. Serum creatinine levels, creatinine clearance, and estimated glomerular filtration rates used in determination of postoperative kidney injury can lead to late detection. Therefore, it is necessary to make a diagnosis earlier in clinical practice and to search for a reliable method. The reliability of the use of serum neutrophil gelatinase-associated lipocalin levels in close follow-up of renal function was evaluated in patients with coronary artery bypass grafting under cardiopulmonary bypass in our study. Patients and Methods. A total of 40 patients who underwent coronary artery bypass grafting under cardiopulmonary bypass between September 2009 and February 2010 were included in the study. The reliability of the postoperative 1st day plasma neutrophil gelatinase-associated lipocalin (Triage (R) NGAL Device; Biosite Inc.) measurements was evaluated in kidney injury developed in the first 5 days after operation that was detected using the Risk-Injury-Failure-Loss-End stage criteria. Results. Ten (25%) women and 30 (75%) male patients were included in the study. The average age is 59 +/- 8.6 years. Kidney injury according to Risk-Injury-Failure-Loss-End stage criteria developed in 8 patients (20%). For 150 ng/mL cutoff value of postoperative plasma neutrophil gelatinase-associated lipocalin levels, the area under the receiver-operating characteristic curve was 0.965. Neutrophil gelatinase-associated lipocalins sensitivity, specificity, and negative and positive predictive values were 100%, 93.8%, 100%, and 80%, respectively. Conclusion. It has been determined that plasma neutrophil gelatinase-associated lipocalin levels can be reliably used for early diagnosis of kidney dysfunction in patients undergoing coronary artery bypass grafting

    The dose-related effects of Dexmedetomidine on renal functions and serum neutrophil gelatinase-associated lipocalin values after coronary artery bypass grafting: a randomized, triple-blind, placebo-controlled study

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    OBJECTIVES: Acute kidney failure after coronary artery bypass grafting (CABG) is a serious complication that increases morbidity and mortality rates. Early detection and prevention of this complication are very important. A novel biomarker named neutrophil gelatinaseassociated lipocalin (NGAL) can play an important role in early diagnosis of acute kidney injury. Recent studies on the favourable effects of Dexmedetomidine on cardiac surgery have been published. The aim of this study is to investigate whether there is a dose-dependent positive effect of Dexmedetomidine on neutrophil gelatinase-associated lipocalin levels and renal functions when used after CABG
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