8 research outputs found
Obesity-Related Oxidative Stress: the Impact of Physical Activity and Diet Manipulation
Obesity-related oxidative stress, the imbalance between pro-oxidants and antioxidants (e.g., nitric oxide), has been linked to metabolic and cardiovascular disease, including endothelial dysfunction and atherosclerosis. Reactive oxygen species (ROS) are essential for physiological functions including gene expression, cellular growth, infection defense, and modulating endothelial function. However, elevated ROS and/or diminished antioxidant capacity leading to oxidative stress can lead to dysfunction. Physical activity also results in an acute state of oxidative stress. However, it is likely that chronic physical activity provides a stimulus for favorable oxidative adaptations and enhanced physiological performance and physical health, although distinct responses between aerobic and anaerobic activities warrant further investigation. Studies support the benefits of dietary modification as well as exercise interventions in alleviating oxidative stress susceptibility. Since obese individuals tend to demonstrate elevated markers of oxidative stress, the implications for this population are significant. Therefore, in this review our aim is to discuss (i) the role of oxidative stress and inflammation as associated with obesity-related diseases, (ii) the potential concerns and benefits of exercise-mediated oxidative stress, and (iii) the advantageous role of dietary modification, including acute or chronic caloric restriction and vitamin D supplementation
Sepoepidemiological stude of Onchocerca volvulus using eluate of blood collected of filter paper
No Abstract. The Nigerian Journal of Parasitology Vol. 21(1) 2000: 33-3
Dimension of Fasciola gigantica recovered from cattle slaughtered in Maiduguri Abattoir, Borno state, Nigeria
No Abstract. The Nigerian Journal of Parasitology Vol. 22(1&2) 2001: 113-11
Soil-transmitted Nematodes and Hygiene Practices in a Rural Community of Benue State, Nigeria
Soil-transmitted nematodes occur mostly in areas where sanitation is poor and environmental conditions favour development of their eggs and larvae. The soil is usually contaminated through indiscriminate defecation while the most common routes of human infection is skin contact and soil contaminated food. [1,8]. The study was carried out in Nyiev-Tiev, Turan, a community in Barakur District, Kwande Local Government Area, Benue State, Nigeria. Fresh stool samples were collected from 250 randomly selected individuals. Parasitological screening of the 250 randomly selected inhabitants of Nyiev-Tiev, Turan in Kwande Local Government Area of Benue State, Nigeria was carried out for soil transmitted nematode. Percentage of infections was 71.2% . The prevalences were as follows: hookworm, 47.6%; Ascaris lumbricoides, 13.6%; Trichuris trichiura 5.2%, and Strongyloides stercoralis 4.8%. Infection was higher among females (72.2%) than males (70.1%) and among age groups; it was highest in those less than 10 years. Among occupations, farmers had the highest prevalence (86.3%) followed by the unemployed (56.2%) and students (48.9%). The result also indicated that among those infected, 10.8% had latrines while 60.4% did not have, 57.1% had good sources of drinking water while 83.3% did not have, and 56.9% had good food hygiene practice while 76.2% did not have, 12.0% had good environmental hygiene practice while 59.2% had poor hygiene practices and 29.2% used foot wears always while 58.0% did not. These differences in were all had statistical relationships except for food hygiene practice and environmental hygiene. These results highlight the significance of occupation, personal and environmental hygiene, as well as sanitation in the transmission of soil- transmitted nematode infections, particularly in the study area. This provided basis for planning effective control against the transmission nof the parasites.Keywords: Hygiene, soil transmitted nematodes, rural community, Benue State, Nigeri
Toxoplasmosis seroprevalence in urban rodents: a survey in Niamey, Niger.
A serological survey of Toxoplasma gondii was conducted on 766 domestic and peridomestic rodents from 46 trapping sites throughout the city of Niamey, Niger. A low seroprevalence was found over the whole town with only 1.96% of the rodents found seropositive. However, differences between species were important, ranging from less than 2% in truly commensal Mastomys natalensis, Rattus rattus and Mus musculus, while garden-associated Arvicanthis niloticus displayed 9.1% of seropositive individuals. This is in line with previous studies on tropical rodents--that we reviewed here--which altogether show that Toxoplasma seroprevalence in rodent is highly variable, depending on many factors such as locality and/or species. Moreover, although we were not able to decipher statistically between habitat or species effect, such a contrast between Nile grass rats and the other rodent species points towards a potentially important role of environmental toxoplasmic infection. This would deserve to be further scrutinised since intra-city irrigated cultures are extending in Niamey, thus potentially increasing Toxoplasma circulation in this yet semi-arid region. As far as we are aware of, our study is one of the rare surveys of its kind performed in Sub-Saharan Africa and the first one ever conducted in the Sahel