Reduction of drive for thinness and body dissatisfaction in people with self-reported dysregulated eating behaviors after intermittent theta burst stimulation (iTBS) of the left dorsolateral prefrontal cortex

Aim: This study aimed to explore the effect of intermittent theta burst stimulation (iTBS) of the right and left dorsolateral prefrontal cortex (DLPFC) in people with self-reported dysregulated eating behaviors but without a diagnosis of eating disorders (EDs). Methods: Participants were randomly divided into two equivalent groups according to the side (right or left) of the hemisphere to be stimulated and they were tested before and after a single iTBS session. Outcome measurements were scores on self-report questionnaires assessing psychological dimensions related to eating behaviors (EDI-3), anxiety (STAI-Y), and tonic electrodermal activity. Results: The iTBS interfered with both psychological and neurophysiological measures. Significant variations of physiological arousal after iTBS of both the right and left DLPFC were witnessed by increased mean amplitude of non-specific skin conductance responses. With regard to the psychological measures, the iTBS on the left DLPFC significantly reduced the scores of the EDI-3 subscales drive for thinness and body dissatisfaction. Interestingly, these two scales are two of the three EDI-3 clinic scales (drive for thinness, body dissatisfaction, and bulimia) used as specific markers to assess the onset and/or maintenance of eating disorders. Conclusion: Our results show that the left DLPFC iTBS has an impact on the psychological dimensions that are risk factors for the onset of eating disorders, suggesting that an altered hemispheric asymmetry similar to that encountered in clinical populations is present in normal subjects even in the absence of clinical symptoms

Air quality data for Catania: analysis and investigation case study: 2010-2011

Abstract This paper focuses on the principal atmospheric pollutants monitored in Catania (Italy) according to European Directive 50/2008. A couple of years, 2012 and 2013 have been considered as a study period. The monitoring system of Catania is made up of five stations that control the presence of the air pollutants in the most important anthropic areas of the urban territory. First of all the mechanisms of formation of the main pollutants have been summarized in order to identify the main causes and effects in urban environment. The raw data have been collected and validated according the UNI CEI EN ISO/IEC 17025:2005 by the Ecologic and Environmental research unit of the municipality of Catania. The trend of all pollutants during the two cited years have been investigated and the results highlight that the most principal polluting gas is NO 2 confirming the trend of the previous years. A further analysis of what the principal causes of pollution in Catania could be,has been conducted in order to evaluate possible actions to reduce the atmospheric pollution. As a result it has been demonstrated that the principal cause of the atmospheric pollutant emissions is connected to private urban mobility. The experimental results demostrated that the principal cause of the atmospheric pollutant emissions is connected to private urban mobility. A development of realistic mathematical model will be the object of future research works

Scaffolded programming projects to promote computational thinking

In Uruguay, Plan Ceibal drives the complex task to impulse computational thinking in public schools. The CT framework used by the organization is to introduce computer science from primary and secondary education, with an approach focused on solving problems and coding as a language, and with the intention of taking advantage of the potential of computational thinking. In order to educate users and creators of technology. In 2021 the Computational Thinking program of Plan Ceibal impacted nearly 40 thousand students and teachers, this represents about 30% of the enrollment for K 4 to 6 courses (9 to 11 years old) of the public elementary school. This study explored the impact of the implementation of scaffolded programming projects and final evaluation, in a subset of elementary schools groups. Preliminary results suggest a good adoption of the program and high participation of students and teachers registered through the learning management system (LMS) platform. In addition, the students who had more active participation in the classes had significantly higher performances in the programming tests. Some differences were observed in favor of girls. Results are discussed in relation to the pedagogical characteristics of the program

Boosting Phonological Fluency Following Leftward Prismatic Adaptation: A New Neuromodulation Protocol for Neurological Deficits?

Prism adaptation (PA) has been recently shown to modulate a brain frontal-parieto-temporal network, with an increase of excitation of this network in the hemisphere ipsilateral to the side of prismatic deviation. This effect raises the hypothesis that left prismatic adaptation, modulating the excitability of frontal areas of the left hemisphere could modulate subjects’ performance on linguistic tasks that map on those areas. To test this hypothesis, sixty-one healthy subjects participated in experiments in which leftward, rightward or no-PA were applied before the execution of a phonological fluency task, i.e. a task with the strict left hemispheric lateralization and mapping onto frontal areas. Leftward-PA significantly increased the number of words produced compared with the pre-PA (p = .0017), R-PA (p=.00013) and no-PA (p=.0005) sessions. In contrast, rightward-PA did not significantly modulate phonological fluency compared with the pre-PA (p = .92) and no-PA (p = .99) sessions. The effect of leftward PA on phonological fluency correlated with the magnitude of spatial aftereffect, i.e. the spatial bias towards the side of space opposite to prismatic deviation following prisms removal (r = .51; p = .04). The present findings document for the first time modulation of a language ability following prismatic adaptation. The results could have a huge clinical impact on neurological populations, opening new strategies of intervention for language and executive dysfunctions

Improvement of phonemic fluency following leftward prism adaptation

Anatomo functional studies of prism adaptation (PA) have been shown to modulate a brain frontal-parieto-temporal network, increasing activation of this network in the hemisphere ipsilateral to the side of prism deviation. This effect raises the hypothesis that left prism adaptation, modulating frontal areas of the left hemisphere, could modify subjects' performance on linguistic tasks that map on those areas. To test this hypothesis, 51 healthy subjects participated in experiments in which leftward or rightward prism adaptation were applied before the execution of a phonemic fluency task, i.e., a task with strict left hemispheric lateralization onto frontal areas. Results showed that leftward PA significantly increased the number of words produced whereas rightward PA did not significantly modulate phonemic fluency. The present findings document modulation of a language ability following prism adaptation. The results could have a huge clinical impact in neurological populations, opening new strategies of intervention for language and executive dysfunctions

Dietary habits and thyroid cancer risk: A hospital-based case-control study in Sicily (South Italy).

Abstract Several studies have investigated the role of diet as a risk and/or protective factor against thyroid cancer, both considering individual foods, groups of foods and dietary patterns, but the results are not consistent. The aim of the study was to investigate the relationship between dietary habits and thyroid cancer. Cases and controls were recruited at the University Hospital "G. Rodolico" of Catania. The dietary habits were defined through the "Lifestyle Assessment Questionnaire". The frequency of consumption of each food item was reported on a 4-level scale (never, one time a week, 2–3 times a week, every day of the week). We computed the odds ratios (ORs) of thyroid cancer and the corresponding 95% confidence intervals (CIs) according to the median of control group daily intake of each food group, using multiple logistic regression models adjusted for major confounding factors. Starchy foods (OR = 1.39, 95% CI 0.83–2.32), sweets (OR = 1.39, 95% CI 0.81–2.40) and products rich in salt and fat showed a positive association with thyroid cancer risk. Conversely, an inverse association with disease risk was found for vegetables (cruciferous OR = 0.30, 95% CI 0.10–0.92, non cruciferous OR = 0.57 (0.20–1.57) milk and dairy products (OR = 0.68, 95% CI 0.40–1.13) and seafood (OR = 0.68, 95% CI 0.34–1.22). An increased risk was observed for consumption of iodized salts (OR 2.06, 95% CI 1.21–3.51), tea (OR = 1.42, 95% CI 0.84–2.41) and coca-cola (OR = 3.08, 95% CI 1.53–6.20). Finally, our results confirm the protective effect of a daily water intake of 1–2 L, but unfortunately this quantity is usually consumed by about a quarter of the sample. Dietary habits appear to modify the risk of thyroid carcinoma. A diet with a limited consumption of starchy foods, products rich in salt, fat and sugar and a higher consumption of, cruciferous/non-cruciferous vegetables, milk and dairy products and seafood could be protective towards thyroid cancer. Moreover, the water intake should be increased and the actual need to consume iodized salt should be verified for each subject/area. These results warrant further investigations and, if confirmed, they might have important public health implications for the reduction of thyroid cancer through the improvement of dietary habits

Performance of Nickel-Iron nanostructured electrodes at different temperatures

In recent years, the whole world has been trying to reduce CO2 emissions through the global decarbonization of energy processes. In this view, the interest towards green hydrogen has drastically increased. One way to produce green hydrogen is by water electrolysis using only electricity from renewable sources. The storage of renewable solar or wind electricity is a major challenge to build a sustainable future energy system. The electrochemical production of hydrogen, through electrolysers, is a viable strategy to take advantage of the surplus electricity coming from renewable energy sources. Its production is pollution-free but is not economically viable. The development of more efficient electrolysers with low-cost electrode materials plays a key role. Catalysts must have such as good electrocatalytic properties, high conductivity, high availability, low cost, and good chemical stability. Nowadays, research is focused on improving the Alkaline Water Electrolysis (AE) to reduce the cost of electrode production. In alkaline environment it was demonstrated that, transition metals, and in particular Nickel or nickel based alloy nanostructured electrodes, have good and stable performances. Furthermore, industrial alkaline electrolysers work at temperatures between 40 and 90°C. Therefore, electrodes must be mechanically and chemically stable at these temperatures. An approach to improve AE performance consists on the fabbrication of nanostructured electrodes because they are characterized by high electrocatalytic activity due to the very high surface area. Starting from the results obtained in a previous work, the nanostructured alloy of NiFe was tested both as cathode and anode at three different temperatures (25 °C, 40 °C, 60 °C). Nanostructured electrodes were obtained through a simple and cheap method, template electrosynthesis, using a polycarbonate membrane as a template. NiFe electrodes morphology was studied by scanning electrode microscopy (SEM) and their composition was evaluated by energy diffraction spectroscopy (EDS) analyses. Later, the electrodes were characterized using various electrochemical techniques: Cyclic Voltammetry (CV), Quasi Steady State Polarization (QSSP) and Galvanostatic Step. To evaluate the mid-term behavior of the electrodes, especially at high temperatures, a constant current density was applied for 6 hours. In particular, -50 mA cm-2 for Hydrogen Evolution Reaction (HER) and 50 mA cm-2 for Oxygen Evolution Reaction (OER). All the tests were performed in 30% w/w KOH aqueous solution. Temperature increase plays a key role in increasing the efficiency of both anode and cathode reactions. As expected, the best result was obtained at 60 °C. Acknowledgments This research was funded by MUR, CNMS Centro Nazionale per la Mobilità sostenibile grant number CN0000002

Nanostructured Ni-Fe-S Based Electrode for Hydrogen Production by Water Electrolysis

Green hydrogen is a real alternative to change the current energy system. Electrochemical water splitting is considered an attractive solution to convert and store the surplus of renewable energy sources. However, hydrogen production by water electrolysis is not economically sustainable due to the use of high noble metals as catalysts (generally platinum or palladium). In order to reduce costs, in this work we have synthesized a ternary alloy of nickel, iron and sulfur and used it as the cathode in an alkaline electrolyzer to produce hydrogen from water. Furthermore, to increase the features of the proposed alloy, this material was synthesized into the pore of a polycarbonate membrane to obtain a nanostructured electrode that exposes a very high surface area to the solution and consequently a large number of electrocatalytic active sites. The electrode fabrication was carried out by potential-controlled pulsed electrochemical deposition where the potential switch from -0.45 V to -1.3 V vs. SCE for 60 cycles. The electrode was characterized by SEM and EDS showing the nanostructured nature and the composition of the electrode. Then it was tested as the cathode in an alkaline electrolyzer (30% KOH) at room temperature. Preliminary results show that the addition of sulfur to the alloy permits to increase in the electrode features compared to the binary alloy of nickel and iron

Selection of the optimal design rainfall return period of urban drainage systems

The aim of this work is to define a methodology to identify the optimal rainfall return period for the design of urban drainage systems. The choice of the optimal return period is made minimizing the total costs of the system: the sewer network is dimensioned for a set of possible design rainfall return periods, and the corresponding construction, maintenance and operation costs are evaluated. For each scenario, the total expected damage from flooding caused by rainfall events with return period greater than the design one is then estimated by hydraulic simulation. This methodology has been applied to a small urban catchment in Palermo (Italy)

Una metodologia per la selezione del tempo di ritorno ottimale della pioggia di progetto delle reti di drenaggio urbano

L'obiettivo del presente lavoro è quello di definire una metodologia per l'individuazione del tempo di ritorno ottimale della pioggia di progetto dell reti di drenaggio urbano