Nova razmatranja malih složenih magnetskih sustava

In this paper, a composed A + B magnetic system, with spins JA = 2 and JB = 3/2, is considered within the mean-field approximation, in the framework of Tsallis nonextensive statistics. Our motivation is twofold: (1) to approach the existing experimental data of manganese oxides (manganites), where Mn3+ and Mn4+ form two magnetic sublattices, and (2) to investigate the structure of nonextensive density matrices of composed systems. By imposing that thermodynamic quantities, such as the magnetization of sublattices A and B, must be invariant whether the calculation is taken over the total Hilbert space or over partial subspaces, we found that the expression for the nonextensive entropy must be adapted. Our argument is supported by the calculation of sublattice magnetizations MA and MB, internal energy, UA and UB and magnetic specific heat, CA and CB. It is shown that only with the modified entropy, the two methods of calculation agree to each other. Internal energy and magnetization are additive, but no clear relationship was found between SA, SB and the total entropy SA+B for q /= 1. It is shown that the reason for the failure of the standard way of calculation is the assumption of statistical independence between the two subsystems, which however does not affect the density matrix in the full Hilbert space.Razmatramo magnetski sustav složen od sastavnica A i B sa spinovima JA = 2 i JB = 3/2 u približenju srednjeg polja i Tsallisove nesveobuhvatne statistike. Dva su povoda: (1) opisati poznate mjerne podatke za manganove okside (manganite), u kojima Mn3+ i Mn4+ tvore dvije magnetske podrešetke, i (2) istražiti strukturu nesveobuhvatne matrice gustoće složenih sustava. Postavljajući da termodinamičke veličine, kao magnetizacija podrešetaka A i B, moraju biti invarijantne kako za račun u cijelom Hilbertovom prostoru, tako i u pojedinim podrešetkama, nalazimo da se izraz za nesveobuhvatnu entropiju mora primijeniti. Naša tvrdnja se zasniva na računu magnetizacije podrešetaka MA i MB, unutarnje energije UA i UB, i magnetske specifične topline, CA i CB. Pokazuje se da su s izmijenjenom entropijom obje metode u skladu. Unutarnja energija i magnetizacija se pribrajaju, ali između SA, SB i ukupne entropije SA+B nismo našli jednostavan odnos za q /= 1. Pokazuje se da je pretpostavka o neovisnosti dvaju podsustava razlog što uobičajen način računanja entropije nije dobar, što ne utječe na račun matrice gustoće u cijelom Hibertovom prostoru

Maintenance of soil fertility on organic farm by modeling of crop rotation with participation alfalfa

The aim of this paper is to maintain soil fertility on an organic farm without livestock production by using alfalfa green biomass. The research was carried out on the farm of Mokrin PP company, by modeling and sizing of crop rotation with alfalfa (Medicago sativa L.) on the non-carbonate humoglay. To ensure a cost-effective technical solution, alfalfa seed production was organized. In the autumn of 2015 alfalfa sowing was carried out in a field of 5 ha. Green biomass of the first and third cuttings, as well as crop residue after harvesting of seeds in the second cutting, were mowed and chopped by harvester for low silage and stored in the silage-pit. After nine months, a mature alfalfa compost was obtained with optimum values of total nitrogen (5.04%), organic matter (42.56%), C/N, pH, humidity, and EC. Two-year alfalfa utilization is the recommended time in this research because to the following benefits: in crop rotation, alfalfa field is provided with nitrogen by symbiotic ni­trogen fixation and the alfalfa is cultivated every five years in the same field, while in the middle of that period the field is fertilized with compost produced on the farm. The amount of compost obtained by crop rotation (2016 - 48.80 t; 2017 - 62.30 t) is enough for about 20% of the arable area per year. Thus, the fields are fertilized every fourth year with 10 t ha-1 of compost. Thanks to alfalfa biomass and seed and also nitrogen fixation, maintaining soil fertility is resolved in a sustainable and natural way

Review of the thermoluminescent dosimetry method for the environmental dose monitoring

Passive solid state dosimeters, such as thermoluminescence dosimeters, provide integrated measurement of the total dose and are widely used in environmental monitoring programs. The objective of this paper is to provide a comprehensive review on the use of thermoluminescent dosimetry methods for monitoring radiation dose in the environment. The article presents the part of the research results of the project PREPAREDNESS (EMPIR 2016 call for Metrology for Environment joint research project) with a particular objective to harmonize procedures used by dosimetry services, relevant authorities and Institutes across the Europe. To achieve this, different monitoring routines that are based on passive environ mental dosimetry methods are investigated. Differences in performing specific steps such as preheating, reading, annealing, minimizing fading, and others, are analyzed. The investigation was performed by means of qualitative literature review that showed the lack of information about specific steps. The conclusion of this work is that thermoluminescent dosimetry measurement system has to be type-tested even though the testing procedure is complicated. In addition to this, control dosimeters should be introduced, International Organization for Standardization protocols should be followed during calibration, and finally, parameters influencing the measurement uncertainty have to be identified and well understood in order to pro duce ac cu rate dose measurement results

Frustration - how it can be measured

A misfit parameter is used to characterize the degree of frustration of ordered and disordered systems. It measures the increase of the ground-state energy due to frustration in comparison with that of a relevant reference state. The misfit parameter is calculated for various spin-glass models. It allows one to compare these models with each other. The extension of this concept to other combinatorial optimization problems with frustration, e.g. p-state Potts glasses, graph-partitioning problems and coloring problems is given.Comment: 10 pages, 1 table, no figures, uses revtex.st

Nonsingular and accelerated expanding universe from effective Yang-Mills theory

The energy-momentum tensor coming from one-parameter effective Yang- Mills theory is here used to describe the matter-energy content of the homogeneous and isotropic Friedmann cosmology in its early stages. The behavior of all solutions is examined. Particularly, it is shown that only solutions corresponding to an open model allow the universe to evolve into an accelerated expansion. This result appears as a possible mechanism for an inflationary phase produced by a vector field. Further, depending on the value of some parameters characterizing the system, the resulting models are classified as singular or nonsingular.Comment: 15 pages, 7 figures, some discussions were simplified and new remarks were introduce

Soluble CD137 as a dynamic biomarker to monitor agonist CD137 immunotherapies

Background On the basis of efficacy in mouse tumor models, multiple CD137 (4-1BB) agonist agents are being preclinically and clinically developed. The costimulatory molecule CD137 is inducibly expressed as a transmembrane or as a soluble protein (sCD137). Moreover, the CD137 cytoplasmic signaling domain is a key part in approved chimeric antigen receptors (CARs). Reliable pharmacodynamic biomarkers for CD137 ligation and costimulation of T cells will facilitate clinical development of CD137 agonists in the clinic. Methods We used human and mouse CD8 T cells undergoing activation to measure CD137 transcription and protein expression levels determining both the membrane-bound and soluble forms. In tumor-bearing mice plasma sCD137 concentrations were monitored on treatment with agonist anti-CD137 monoclonal antibodies (mAbs). Human CD137 knock-in mice were treated with clinical-grade agonist anti-human CD137 mAb (Urelumab). Sequential plasma samples were collected from the first patients intratumorally treated with Urelumab in the INTRUST clinical trial. Anti-mesothelin CD137-encompassing CAR-transduced T cells were stimulated with mesothelin coated microbeads. sCD137 was measured by sandwich ELISA and Luminex. Flow cytometry was used to monitor CD137 surface expression. Results CD137 costimulation upregulates transcription and protein expression of CD137 itself including sCD137 in human and mouse CD8 T cells. Immunotherapy with anti-CD137 agonist mAb resulted in increased plasma sCD137 in mice bearing syngeneic tumors. sCD137 induction is also observed in human CD137 knock-in mice treated with Urelumab and in mice transiently humanized with T cells undergoing CD137 costimulation inside subcutaneously implanted Matrigel plugs. The CD137 signaling domain-containing CAR T cells readily released sCD137 and acquired CD137 surface expression on antigen recognition. Patients treated intratumorally with low dose Urelumab showed increased plasma concentrations of sCD137. Conclusion sCD137 in plasma and CD137 surface expression can be used as quantitative parameters dynamically reflecting therapeutic costimulatory activity elicited by agonist CD137-targeted agents