Psychological assistance to patients with near-death experience (based on foreign research)

Background. Near-death experience is an altered state of consciousness at the time when the person is on the threshold of death. Near-death experience has a specific structure which includes such elements as extra corporal experience, moving in a dark tunnel, seeing bright light, meetings with the deceased persons, panoramic life review and many others. The condition is quite common nowadays particularly due to the success of resuscitation and a high level of emergency care organization). Experience in itself and its some consequences derivate a lot of psychological problems at the person, which he is afraid to tell not only medical staff, but also relatives because of danger of interpretation his (her) near-death experiences as marks of psychic illness. The Objective of the analytical theoretical research was to study the experience of working with such patients, accumulated in Western medicine, psychology and psychotherapy, the organization of the training process and also the organization of psychotherapeutic support for survivors and members of their families. Design. This article analyzes the foreign (most publications on this subject is carried out in the United States) works on the problem of treatment with near-death experiencer and psychological support for them, the material contained in these works is structured and summarized on the main problems in this area. Research results. Based on the review and analysis of the reference literature a preliminary Atwater’s adaptation model of the near-death experience is proposed, the integration of this experience is viewed as the main goal to be implemented by the experiencer independently or in collaboration with a psychotherapist, the universal rules of treating near-death experiencers are elaborated. There are rules of treating different groups of experiencers and different categories of people interacting with them are identified and integrated: the rules of treating children with near-death, the experience of organizing psychotherapeutic assistance to their relatives. Conclusion. The compliance with the rules by physicians, psychotherapists and relatives of near-death patients contributes to the decreased emotional and social problems in the patient, and sometimes even prevents their occurrence

Метгемоглобинемия, ассоциированная с приемом бензокаина. Клинический случай

The article describes a clinical case of the development of a severe, life-threatening methemoglobinemia in a patient with a dystrophic form of congenital epidermolysis bullosa while receiving a drug containing benzocaine. The current data on classification, pathogenesis, clinical course and methods for treating this state has been presented. Many substances and drugs that are methemoglobin formers are widespread and can cause chronic methemoglobinemia. Acute severe methemoglobinemia is accompanied by life-threatening organ disorders. In some cases, it may be difficult to diagnose methemoglobinemia due to the polymorphism of the clinical picture, the need for laboratory confirmation of the diagnosis, which may be underperformed in the absence of adequate alertness. The presented clinical case will be useful for doctors of various specialties.В статье представлено описание клинического случая развития тяжелой, угрожающей жизни метгемоглобинемии у пациента с дистрофической формой врожденного буллезного эпидермолиза на фоне приема препарата, содержащего бензокаин. Приведены современные данные о классификации, патогенезе, клиническом течении и способах терапии указанного состояния. Многие вещества и лекарства, являющиеся метгемоглобинобразователями, широко распространены и могут вызывать хроническую метгемоглобинемию. Острая тяжелая метгемоглобинемия сопровождается угрожающими жизни органными нарушениями. Диагностика метгемоглобинемии в ряде случаев может быть затруднена в силу полиморфизма клинической картины, необходимости лабораторного подтверждения диагноза, которое может быть не выполнено в случае отсутствия должной настороженности. Представленный клинический случай будет полезен для врачей различных специальностей

Implementation of differential scanning calorimetry when studying polymerization of compounds based on glycolic acid ether

Using differential scanning calorimetry and synchronous thermal analysis under dynamic conditions, kinetic regularities of copolymerization of α- glycolide and a mixture of α-β-glycolide with D,L-lactide in the presence of stannous octoate as a catalyst have been investigated. Some thermodynamic and kinetic parameters of cationic copolymerization of monomers have been determined

Implementation of differential scanning calorimetry when studying polymerization of compounds based on glycolic acid ether

Using differential scanning calorimetry and synchronous thermal analysis under dynamic conditions, kinetic regularities of copolymerization of α- glycolide and a mixture of α-β-glycolide with D,L-lactide in the presence of stannous octoate as a catalyst have been investigated. Some thermodynamic and kinetic parameters of cationic copolymerization of monomers have been determined

GM2-gangliosidosis, type I (Tay – Sachs disease) in the pediatrician practice

Background. GM2-gangliosidosis, type I (Tay-Sachs disease) is rare hereditary disease caused by mutations in the HEXA gene encoding the alpha subunit of lysosomal hexosaminidase A. It leads to accumulation of GM2-ganglioside in lysosomes and cell death. The major clinical signs of this disease are regression of motor and psychoverbal skills, progressive macrocephaly, diffuse muscle hypotension, convulsive disorder. Almost all patients with this disease have the “cherry red spot” symptom on the fundus of the eye.Clinical case description. We show clinical description of the patient with disease manifested with the lesion of visual analyzer. The child was sent for geneticist’s consultation due to revealed ophthalmic picture of the “cherry red spot” symptom on the fundus of the eye. Molecular genetic testing has revealed in the patient c.1274_1278 dupTATC (CI 880091) mutation in homozygous state in HEXA gene.Concllusion. Differential diagnosis of this disease should be performed with other diseases from the group of inherited metabolic diseases associated with early regression of psychomotor skills, progressive vision loss, “cherry red spot” symptom on the fundus of the eye and convulsive disorde

Benzocaine-Induced Methemoglobinemia. A Clinical Case

The article describes a clinical case of the development of a severe, life-threatening methemoglobinemia in a patient with a dystrophic form of congenital epidermolysis bullosa while receiving a drug containing benzocaine. The current data on classification, pathogenesis, clinical course and methods for treating this state has been presented. Many substances and drugs that are methemoglobin formers are widespread and can cause chronic methemoglobinemia. Acute severe methemoglobinemia is accompanied by life-threatening organ disorders. In some cases, it may be difficult to diagnose methemoglobinemia due to the polymorphism of the clinical picture, the need for laboratory confirmation of the diagnosis, which may be underperformed in the absence of adequate alertness. The presented clinical case will be useful for doctors of various specialties

Comorbid Cardiovascular Malformation and Type II Mucolipidosis: Clinical Case

Background. Type II mucolipidosis (I-cell disease, ICD) is one of the lysosomal storage diseases. It is very rare disease; the literature describes only few cases with confirmed diagnosis of mucolipidosis. Cardiovascular changes in children with such pathology are even less often. Clinical case description. The article describes the clinical case of type II mucolipidosis alongside with cardiovascular pathology — valvular heart apparatus defect with abdominal aortic hypoplasia and reversible myocardial dysfunction on the therapy of chronic heart failure (CHF). The patient has coarse face, gingival hyperplasia, macroglossia, dysostosis multiplex, diffuse muscular hypotonia, and mass of subcutaneous tissue. Arterial hypertension, heart cavities dilatation, left ventricular (LV) walls hypertrophy, and data of CT aortography let us to diagnosis abdominal aortic hypoplasia. Conclusion. Cardiovascular malformation in patients with mucolipidosis leads to severe, life-threatening conditions development. Untimely diagnosis can worsen the course of disease. Multidisciplinary approach is needed for the patient management