476 research outputs found

    Media Competence as an Integral Quality of a New Teacher for a New School

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    The proposed article considers the issue of social and cultural determinants having impact on qualitative alteration of requirements to teacher’s personality, media competence as an integral property of a new teacher for a new school. The main ideas of media education’s development are represented in the social-humanitarian context of realization of presidential initiatives “Our New School” which reflect subjective aspect of interpreting the category “media competence” in a wide social and cultural meaning

    Practical designs for Phase I combination studies in oncology

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    Phase I trials evaluating the safety of multi-drug combinations are becoming more common in oncology. Despite the emergence of novel methodology in the area, it is rare that innovative approaches are used in practice. In this article, we review three methods for Phase I combination studies that are easy to understand and straightforward to implement. We demonstrate the operating characteristics of the designs through illustration in a single trial, as well as through extensive simulation studies, with the aim of increasing the use of novel approaches in phase I combination studies. Design specifications and software capabilities are also discussed

    The Eurasian economic union customs’ administration mechanism in the digital era

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    Purpose: The aim of the article is to identify the prospects for the Eurasian Economic Union (EEU) customs regulation mechanism in digital transformation following the global trend. Design/Methodology/Approach: For the purpose of determining priorities for the EEU customs mechanism digitization, it is necessary to define the regulatory framework on which the digitalization process is based, to analyze the customs’ regulation sphere digitization direction in the member states of the EEU and to formulate the priorities for improving the EEU customs’ regulation mechanism on the information and communication technologies. Findings: EEU customs’ regulation mechanism digitization key areas have been identified, based on the provisions of the EEU’s Digital Agenda and the Declaration on further development of integration processes within the Union. Practical implications: The results can be implemented in the Eurasian Economic Commission management practice, the EEU member states customs’ authorities in order to improve the customs regulation mechanism. Originality/Value: The main contribution of this study is to identify the differences in the customs regulation sphere digitization processes in the EEU member states and to identify the areas for implementing a unified strategy.peer-reviewe

    Electron-ion plasma modification of Al-based alloys

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    The paper reports on the study where we analyzed the surface structure and strength properties of coated Al alloys modified by electron-ion plasma treatment. The Al alloys were deposited with a thin (≈0.5 μm) TiCu film coating (TiCu-Al system) and with a hard TiCuN coating (TiCuN–AlSi system) on a TRIO vacuum setup in the plasma of low-pressure arc discharges. The temperature fields and phase transformations in the film–substrate system were estimated by numerical simulation in a wide range of electron energy densities (5–30 J/cm2) and pulse durations (50–200 μs). The calculations allowed us to determine the threshold energy density and pulse duration at which the surface structure of the irradiated Al-based systems is transformed in a single-phase state (solid or liquid) and in a two-phase state (solid plus liquid). The elemental composition, defect structure, phase state, and lattice state in the modified surface layers were examined by optical, scanning, and transmission electron microscopy, and by X-ray diffraction analysis. The mechanical characteristics of the modified layers were studied by measuring the hardness and Young’s modulus. The tribological properties of the modified layers were analyzed by measuring the wear resistance and friction coefficient. It is shown that melting and subsequent high-rate crystallization of the TiCu–Al system makes possible a multiphase Al-based surface structure with the following characteristics: crystallite size ranging within micrometer, microhardness of more than 3 times that in the specimen bulk, and wear resistance ≈1.8 times higher compared to the initial material. Electron beam irradiation of the TiCuN–AlSi system allows fusion of the coating into the substrate, thus increasing the wear resistance of the material ≈2.2 times at a surface hardness of ∼14 GPa

    Tendências atuais no estado e regulação legal do componente religioso na educação

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    The article presents the results of modern model comparative legal analysis concerning state and legal regulation of the religious component in education within the context of state and municipal educational organization profile activity. The conceptual features of such regulation optimal model are determined, claiming the status of universal ones; their uniform consolidation in the special educational legislation of modern secular states is justified.El artículo presenta los resultados del análisis jurídico comparativo del modelo moderno sobre la regulación estatal y legal del componente religioso en la educación dentro del contexto de la actividad de perfil de la organización educativa estatal y municipal. Se determinan las características conceptuales de dicho modelo de regulación óptima, reclamando el estado de los universales; su consolidación uniforme en la legislación educativa especial de los estados seculares modernos está justificada.O artigo apresenta os resultados do modelo moderno de análise comparativa da legislação estadual e jurídica sobre o componente religioso na educação no contexto da atividade de perfil das organizações educacionais estaduais e municipais. As características conceituais desse modelo ótimo de regulação são determinadas, reivindicando o status das universais; sua consolidação uniforme na legislação educacional especial dos estados seculares modernos é justificada

    Improvement of financial literacy as a crucial factor of economic development

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    Issues on the public financial literacy are highly relevant in the context of expanding opportunities of financial services used, increasing the complexity and the appearance of new financial tools. Ensuring personal financial security is becoming an important factor of economic development and public welfare improvement. Nevertheless, a low level of financial literacy negatively impacts personal welfare and a financial potential of households, deteriorates the resource base of financial institutions, hampers the financial market development, retards investment processes in economics and leads to the aggravation of the socio-economic situation of the country. In this regard, the following tasks have been set in this study. To consider a conceptual characteristic of the notion “financial literacy” and its components – fiscal and taxation literacy; study the contemporary international and Russian practice of financial literacy improvement as a factor for the economic development of a country. The article substantiates the following: the constructive use of the best practices should create real opportunities for raising the level of financial literacy of the population in the Russian Federation, increase confidence in the financial system, reduce the financial risks of consumers of financial services and improve the population’s welfare.peer-reviewe

    Glutamate Concentration in the Serum of Patients with Schizophrenia

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    Glutamate is the major neurotransmitter with multiple functions in the central nervous system. Glutamate-mediated excitotoxicity is involved in the pathophysiological processes in schizophrenia. The purpose of this study was to determine the concentration of glutamate in the serum of patients with paranoid schizophrenia compared with healthy individuals, and depending on the duration of the schizophrenic process and leading clinical symptoms. We investigated the level of glutamate in the serum of 158 patients with paranoid schizophrenia and 94 healthy persons. Higher concentrations of glutamate in schizophrenic patients compared with healthy persons have been found. The maximum concentrations of glutamate were detected in patients with disease duration of more than ten years. Glutamate level in the serum does not depend on the prevailing negative or positive clinical symptoms. The increased concentration of glutamate can hypothetically contribute to dopaminergic and glutamatergic imbalance, leading to the development of psychotic symptoms and cognitive dysfunction
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