20 research outputs found
Improved methods for purification and depletion of monocytes from bovine peripheral blood mononuclear cells. Functional evaluation of monocytes in responses to lectins
Get PDFPhosphorylation differences among proteins of bloodstream developmental stages of Trypanosoma brucei brucei
Full text linkIngi, a 5.2-kb dispersed sequence element from Trypanosoma brucei that carries half of a smaller mobile element at either end and has homology with mammalian LINEs.
No full textSequential cleavage of proinsulin by human pancreatic kallikrein and a human pancreatic kininase
No full textPathology of Tnf-deficient mice infected with Plasmodium chabaudi adami 408XZ
No full textTumor necrosis factor alpha (Tnf) plays a pleiotropic role in murine malaria. Some investigations have correlated Tnf with hypothermia, hyperlactatemia, hypoglycemia, and a suppression of the erythropoietic response, although others have not. In this study, we have evaluated parasitemia, survival rate and several pathological features in C57BL/6JTnf(-/-) and C57BL/6JTnf(+/+) mice after infection with Plasmodium chabaudi adami 408XZ. Compared to the C57BL/6JTnf(+/+) mice, C57BL/6JTnf(-/-) mice showed increased parasitemia and decreased survival rate, whereas blood glucose, blood lactate and body weight were not significantly different. However, C57BL/6JTnf(-/-) mice suffered significantly more from severe anemia and hypothermia than C57BL/6JTnf(+/+) mice. These results suggest that Tnf is an important mediator of parasite control, but not of anemia development. We hypothesize that the high mortality observed in the Tnf knock-out mice is due to increased anemia and pathology as a direct result of increased levels of parasitemia
Characterization of trypanosome isolates from cattle in Uganda using species-specific DNA probes reveals predominance of mixed infections
No full textSome Properties of Human Pancreatic Kallikrein and Comparison with Human Trypsins and Porcine Kallikrein
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