24 research outputs found
Endogenous development of two Coccidian parasites : Isospora arctopitheci and Sarcocystis hemionilatrantis
The Limited Agency and Life-cycles of Personalised Dominant Parties in the post-Soviet space: the cases of United Russia and Nur Otan
Vladimir Putin's United Russia and Nursultan Nazabayev's Nur Otan represent a distinctive type of dominant party due to their personalist nature and dependence on their presidential patrons. Such personalism deprives these parties of the agency to perform key roles in authoritarian reproduction typically expected of dominant parties, such as resource distribution, policy-making and mobilizing mass support for the regime. Instead United Russia and Nur Otan have contributed to authoritarian consolidation by securing the president's legislative agenda, stabilizing elites to ensure their patron's hold on power, and assisting in perpetuating a discourse around the national leader. However, because these parties lack the agency to reproduce themselves, to entrench their position, and to play more than a supportive role in regime consolidation, the lifespan of such personalist dominant parties is likely to be significantly shorter than that of dominant parties
Genotype and Gene Expression Associations with Immune Function in Drosophila
It is now well established that natural populations of Drosophila melanogaster harbor substantial genetic variation associated with physiological measures of immune function. In no case, however, have intermediate measures of immune function, such as transcriptional activity of immune-related genes, been tested as mediators of phenotypic variation in immunity. In this study, we measured bacterial load sustained after infection of D. melanogaster with Serratia marcescens, Providencia rettgeri, Enterococcus faecalis, and Lactococcus lactis in a panel of 94 third-chromosome substitution lines. We also measured transcriptional levels of 329 immune-related genes eight hours after infection with E. faecalis and S. marcescens in lines from the phenotypic tails of the test panel. We genotyped the substitution lines at 137 polymorphic markers distributed across 25 genes in order to test for statistical associations among genotype, bacterial load, and transcriptional dynamics. We find that genetic polymorphisms in the pathogen recognition genes (and particularly in PGRP-LC, GNBP1, and GNBP2) are most significantly associated with variation in bacterial load. We also find that overall transcriptional induction of effector proteins is a significant predictor of bacterial load after infection with E. faecalis, and that a marker upstream of the recognition gene PGRP-SD is statistically associated with variation in both bacterial load and transcriptional induction of effector proteins. These results show that polymorphism in genes near the top of the immune system signaling cascade can have a disproportionate effect on organismal phenotype due to the amplification of minor effects through the cascade
The Resource Curse and Rentier States in the Caspian Region : A Need for Context Analysis
Although much attention is paid to the Caspian region with regard to energy issues, the domestic
consequences of the region’s resource production have so far constituted a neglected field of research.
A systematic survey of the latest research trends in the economic and political causalities of
the resource curse and of rentier states reveals that there is a need for context analysis. In reference
to this, the paper traces any shortcomings and promising approaches in the existent body of literature
on the Caspian region. Following on from this, the paper then proposes a new approach; specifically,
one in which any differences and similarities in the context conditions are captured. This
enables a more precise exploration of the exact ways in which they form contemporary post-Soviet
Caspian rentier states.Obwohl der Region am Kaspischen Meer im Zuge von Energiediskursen groĂźe Aufmerksamkeit zuteil
wird, stellen die innerstaatlichen Folgen der Ressourcenproduktion in der Region ein bislang
vernachlässigtes Forschungsfeld dar. Ein systematischer Überblick über die jüngsten Forschungstrends
zu wirtschaftlichen und politischen Kausalzusammenhängen des Ressourcenfluchs und zu
Rentierstaaten offenbart die Notwendigkeit von Kontextanalysen. Hierauf Bezug nehmend, analysiert
der Aufsatz sowohl die Mängel als auch viel versprechende Ansätze in der betreffenden Literatur
zur Region am Kaspischen Meer. Der Aufsatz stellt letztendlich einen neuen Ansatz vor, der
Unterschiede und Gemeinsamkeiten in den Kontextbedingungen erfasst, um zu erforschen, wie diese
die gegenwärtigen post-sowjetischen Rentierstaaten in der Region am Kaspischen Meer tatsächlich
prägen
The Resource Curse and Rentier States in the Caspian Region: A Need for Context Analysis
Andrew Olcott : On Architecture and the Body
Brodie reflects on three photo-based works in which Olcott "uses the body and architecture as iconography of contemporary society." Artist's statement. Brief biographical notes