A Rough Set Approach to Dimensionality Reduction for Performance Enhancement in Machine Learning

Machine learning uses complex mathematical algorithms to turn data set into a model for a problem domain. Analysing high dimensional data in their raw form usually causes computational overhead because the higher the size of the data, the higher the time it takes to process it. Therefore, there is a need for a more robust dimensionality reduction approach, among other existing methods, for feature projection (extraction) and selection from data set, which can be passed to a machine learning algorithm for optimal performance. This paper presents a generic mathematical approach for transforming data from a high dimensional space to low dimensional space in such a manner that the intrinsic dimension of the original data is preserved using the concept of indiscernibility, reducts, and the core of the rough set theory. The flue detection dataset available on the Kaggle website was used in this research for demonstration purposes. The original and reduced datasets were tested using a logistic regression machine learning algorithm yielding the same accuracy of 97% with a training time of 25 min and 11 min respectively

Effects of spent engine oil contamination on soybean (Glycine max L. Merril) in an Ultisol

An experiment was conducted in the University of Nigeria Nsukka Teaching and Research Farm to determine the effect of spent auto-engine oil on soil and soybean in a Randomized Complete Block Design. Treatments were four levels (0, 1, 2 and 3 %) of spent auto-engine oil (SPO). Top soil samples were collected at 0, 12, 24 and 36 months and analyzed. Results indicated that infiltration rates in plots under 3 % SPO was reduced from 1.40 cm h-1 in control plots to the lowest value of 0.07 cm h-1 compared to 0.27 cm h-1 in 1 % treatment in the first 12 months. Plots contaminated with 3 % SPO gave the lowest Ks values of 6.29, 7.68 and 9.43 cm h-1 in the 12th, 24th and 36th months respectively. Data on plant samples showed that 2 % and 3 % SPO contaminations reduced soybean germination from 99 % (control) to 86 and 68 % respectively in the first cropping season whereas 1 % SPO was observed to significantly increase leaf area, dry matter content and grain yield from control values of 52.6 cm2, 3.01 t ha-1 and 0.72 t ha-1 to 54.5 cm2, 4.20 t ha-1 and 0.97 t ha-1 respectively.Keywords: Contamination, soybean, soil physical properties, spent engine oil, Ultiso

Effect of optimizing process variables on the quality characteristics of cassava-wheat composite bread

The optimisation of bread-making process can have a positive impact in ramping up the quality characteristics of cassava-wheat bread to  that of whole wheat bread. In this study, a threevariable Box-Behnken design response surface methodology was employed to investigate and optimise independent variables namely cassava flour composition, water content and proofing time in relation to response variables namely dough yield, loaf specific volume and loaf protein of cassava-wheat-composite bread. The data from the experimental design were fitted into second-order regression models and their validity and reliability were confirmed by analysis of variance. Optimal cassava flour composition, water content and proofing time were derived as; 100 g/kg, 589 g/kg and 90 min, respectively. It was revealed that cassava flour composition had the most effect on the quality characteristics of cassava-wheat-composite bread. At constant cassava flour  composition, increase in water content and proofing time had a positive effect on all the studied quality characteristics of cassava-wheat composite bread. Increase cassava flour composition regardless of proofing time and water content had a negative effect on loaf specific volume and protein. This study has provided bread-making conditions which can be utilised in enhancing the consumer acceptability of cassava-wheat composite bread. &nbsp

Biochemical Changes in Alloxan - Induced Diabetes Rat Liver and Kidney Dosed Artesunate

Diabetes is a disease marked by elevated blood sugar levels, and the second leading cause of renal diseases and blindness worldwide. Artesunate is an antimalarial drug, that has been reported to have hypoglycemic potential, but to the best of our knowledge, much work has not been done to explore the biochemical and clinical implications of administration of artesunate on a diabetic subject. This study investigates biochemical changes in terms of oxidative status associated with oral administration of artesunate on diabetic animal model. Twenty eight male Wistar rats weighing averagely 200g were divided into four groups of seven rats each, Group A-control, B- Diabetes only, C- Artesunate only, D- Diabetes + Artesunate. Diabetes was induced intraperitoneally, at a single dose of Alloxan(160mg/kg body weight(bw). Artesunate was administered orally in aqueous solution at 2.90mg/kg bw on day one, and at 1.45mg/kg bw on the subsequent 7days. Spectrophotometric technique was used for biochemical analysis in serum, kidney and liver homogenates. Aspartate amino transferase (AST) and Alanine amino transferase (ALT) activities as well as Creatinine concentration were significantly (P<0.05) increased in group B compared with control, while group D showed a significant (P<0.05) decrease compared with group B. Total protein concentration was significantly(P<0.05) increased in group B compared with control, while group D  showed an insignificant  decrease compared  with group B. Moreover, Superoxide dismutase(SOD) and Catalase(CAT) activities as well as  Reduced glutathione (GSH) concentration were significantly(P<0.05) decreased in group B compared with control, and were restored near to the control level significantly (P<0.05) in group D, compared with group B. Malondialdehyde (MDA) concentration was significantly (P<0.05) increased in group B compared with control, but was reversed significantly (P<0.05) in group D compared with group B. Artesunate ameliorates oxidative stress in diabetic rats liver and kidney, possess hypoglycemic effect, hence antioxidant and hypoglycemic effects of artesunate may be beneficial to diabetic liver and kidney. Keywords: Artesunate, Diabetes mellitus, Hypoglycemia, Alloxan, Antioxidant. DOI: 10.7176/ALST/72-03 Publication date:March 31st 201

Lamivudine-Induced Liver Injury

BACKGROUND: Lamivudine is a nucleoside analogue antiretroviral drug, known for its low toxicity at clinically prescribed dose. However, the toxicity or mechanism of toxicity and target tissue effects during prolonged administration of higher doses were hardly given sufficient laboratory attention. AIM: The present work was designed to investigate the biochemical and histopathological changes in the liver of rat administered with prolonged doses of lamivudine. MATERIAL AND METHODS: Lamivudine in multiple doses of five ranging from 4 mg/kg to 2500 mg/kg were administered, in vitro, by injection into the air-sac of 10–day old fertile embryonated eggs of Gallus domesticus. Also, female rats of the Wistar strain received oral doses, up to 500 mg/kg singly or repeatedly for 15 or 45 days, respectively. Spectrophotometric techniques were employed to monitor activities of the aminotransferases (ALT and AST), γ–glutamyltransferase (GGT) and total protein concentration in serum while activities of glutathione S–transferase (GST), GGT and superoxide dismutase (SOD) as well as concentrations of malondialdehyde (MDA) and protein were determined in liver. Histopathological studies were carried out on liver. Data were analysed using ANOVA and were considered significant when p < 0.05. RESULTS: The LD50 for the drug calculated from the incubation experiment was 427 mg/kg. Total serum protein concentration significantly reduced while enzymes activities significantly increased at 500 mg/kg only among the repeat-dosed rats. Hepatic GGT, GST and SOD activities as well as MDA concentration were significantly elevated at 20 mg/kg. Histopathological studies showed multifocal lymphoid cell population in the liver sinusoid of the chicken and hydropic degeneration of hepatocytes were recorded among rats repeatedly exposed to the drug respectively at doses ≥ 100 mg/kg

Preparation, Release Pattern and Antibacterial Activities of Chitosan-Silver Nanocomposite Films

The present study examined the preparation of chitosan-silver   nanocomposite films as carriers for silver release pattern. Chitosan a biopolymer   having immense structural possibilities for chemical and mechanical modifications   to generate novel properties, functions and applications. Chitosan–silver   nanocomposite films has been synthesised by reduction method, which is a simple   and inexpensive method. The chitosan-silver nanocomposite films was   characterized in terms of its surface plasmon resonance and crystalline structure by   using UV-Visible spectroscopy, X-ray diffraction, Fourier transform infrared and   Scanning electron microscope. Swelling and release studies were carried out on   crosslinked and un-crosslinked nanocomposite films. Antibacterial activities of   chitosan-silver nanocomposite films were investigated on some pathogens:   Staphylococcus aureus, Shigella dysenteriae, Escherichia coli, Salmonella typhii   and Klebsiella pneumonia using agar well diffusion method. crosslinked chitosan-silver nanocomposite demonstrated a slower release pattern relative to un-crosslinked chitosan-silver nanocomposite. The crosslinked and un-crosslinked   nanocomposite became dislodged and completely released at 120 minutes and 90   minutes respectively. The results of the antibacterial activities revealed that the   cross-linked chitosan-silver nanocomposite films has higher antibacterial   properties than un-crosslinked chitosan-silver nanocomposite films. This study   provides nanocomposite films potentially useful for delivery system.</p

Prediction Models for Water Erosion Risk Management: A Review

In order to estimate the potential soil erosion hazard of an area, erosion prediction models are needed. Various models have been used by researchers, which ranges from mathematical and conceptual simple approaches to complex models that try to include the complexities of the real world. Six (6) models are reviewed in relation to their suitability for use. The KINEROS, CORINE and EUROSEM were best suited for water erosion risk prediction in cultivated soils. On the other hand, the KINEROS, PESERA, CORINE and EUROSEM were found to be applicable in all sectors (Agronomy, water resources management and road construction) highlighted. The GLASOD had the least applicability with respect to this study.Keywords: Water Erosion, sediment transport models, Model structure and suitability for us

Quality Assessment of Selected Public Recreational Waters in Sango-Ota Metropolis, Nigeria

The evaluation of selected public swimming pools within Sango-Ota metropolis was done to determine whether the pools adapt to the recommended WHO standard for swimming pool water. Six pools were selected based on the average population per use and user ratings. A total of 12 water samples were analysed physicochemical and microbial qualities using standard methods. The&nbsp; physicochemical characterization results are as follows; pH, 5.00 - 5.73 with mean value of 5.3; Total Dissolved Solids (TDS), 44.00 - 48.50 mg/L with mean 46.0 mg/L; Alkalinity, 24.00 - 28.50 mg/L with mean 26.0 mg/L; total hardness, 0.80 - 1.23 mg/L with mean 1.0 mg/L; iron, 0.05 – 0.69 mg/L with mean 0.3 mg/L; residual chlorine, 1.06 – 3.25 mg/L with mean 1.9 mg/L. The microbial characterization results are as follows; Zero count for Salmonella-shigella; Total Aerobic Plate Count (TAPC),1360 - 7270 cfu/mL; Escherichia coli count, 0 - 7 cfu/mL; coliform count, 2 – 25 cfu/mL.&nbsp; The isolated microorganisms from the pools were Escherichia coli, Proteus Vulgaris, Yersinia Enterocolitica, Proteus Mirabilis, Citrobacter Freundi and Vibro Chlorea occurred in 8.33%, respectively while Klebsiella Pneumonia, Entrobacter Aerogenes, Pseudonomas sp. occurred 16.67%. The pH of the analysed pools didn’t comply with the WHO standards while other physicochemical parameters conform to the standard except for pools C and F which had a higher concentration of iron. However, the existence of pathogenic microorganisms in the pools classified them as unsafe for swimming activities. This study recommends routine testing and comprehensive treatments with respect to regulatory standards.&nbsp; Pool managers should strictly adhere to the bathing load limit and ensure the pool users take shower before using the swimming pools to forestall the outbreak of waterborne disease

The Social and Political Dimensions of the Ebola Response: Global Inequality, Climate Change, and Infectious Disease

The 2014 Ebola crisis has highlighted public-health vulnerabilities in Liberia, Sierra Leone, and Guinea – countries ravaged by extreme poverty, deforestation and mining-related disruption of livelihoods and ecosystems, and bloody civil wars in the cases of Liberia and Sierra Leone. Ebola’s emergence and impact are grounded in the legacy of colonialism and its creation of enduring inequalities within African nations and globally, via neoliberalism and the Washington Consensus. Recent experiences with new and emerging diseases such as SARS and various strains of HN influenzas have demonstrated the effectiveness of a coordinated local and global public health and education-oriented response to contain epidemics. To what extent is international assistance to fight Ebola strengthening local public health and medical capacity in a sustainable way, so that other emerging disease threats, which are accelerating with climate change, may be met successfully? This chapter considers the wide-ranging socio-political, medical, legal and environmental factors that have contributed to the rapid spread of Ebola, with particular emphasis on the politics of the global and public health response and the role of gender, social inequality, colonialism and racism as they relate to the mobilization and establishment of the public health infrastructure required to combat Ebola and other emerging diseases in times of climate change

Effects of Design Studio Culture on Creativity of Architecture Students

Architectural education will not be complete without due reference to its studio culture. This Culture consists of habits, patterns and experiences expressed by students in their design studio. The design studio culture has been observed to have affect creativity of students over the years. This paper examines the effect of design studio culture already existing from the review of literature. The study survey method was adopted to obtain quantitative data from the students through the use of structured questionnaires which were administered in the selected schools in southwest Nigeria. The data gotten were subjected to factor and regression analysis using the statistical package for social sciences (SPSS). Results gotten showed that the students perceived the other factors to be the core components of design studio culture in addition to those already identified in the review of literature. The findings also indicated that only five(5) of these components affects architecture students’ creativity. This paper recommends that the awareness of studio culture should be promoted through the departmental policies as a way of improving students creativity. Findings for this study are expected to provide the universities with empirical grounds that will aid policies and reforms directed at improving academic performance of architecture students