Detection of subependymal veins using high-resolution magnetic resonance venography

High-resolution magnetic resonance venography (HR-MRV) of intracranial subependymal veins using a two-dimensional Fourier-transform time-of-flight technique was performed on normal volunteers and clinical cases of cerebral disease. For the pulse sequence, fast-field-echo sequence was used with the following parameters: TR/TE/ flip angle = 34ms/12ms/50deg., 256 x 256 matrix, 1 mm effective slice thickness, 150mm field of view, and one signal acquisition. Sequential vertical coronal sections were taken against the skull base. The anterior septal vein, the medial atrial vein, the anterior caudate vein and thalamostriate vein were detected in all subjects. In all clinical cases, HR-MRV was equal in diagnostic capability to conventional cerebral angiography.</p

Detection of morulae in peripheral blood neutrophils from two dogs with Anaplasma phagocytophilum infection in Japan

Morulae are cytoplasmic inclusions found in granulocytes of mammals infected by Anaplasma phagocytophilum. Two dogs presented with acute anorexia and lethargy in 2018, and both exhibited fever and thrombocytopenia as clinicopathological findings. Hematological examination of blood smears revealed cytoplasmic inclusions in neutrophils, which were confirmed as A. phagocytophilum infection with serological and molecular methods. Sequencing of partial 16S rRNA genes revealed highest homologies to the A. phagocytophilum sequence from a case of canine granulocytic anaplasmosis in Japan. This is the first report of morulae appearance with canine granulocytic anaplasmosis in Japan