Operability of Mobile Agent Applications in a Protected Environment

There is a shift toward increasingly heterogeneous networks in today�s communications environment. Such diversity requires that network operators have greater experience and increased training. Managing these diverse networks especially in institutions requires the collection of large quantities of data from a dependable network that must be analyzed before management of any activity can be comenced. In this research, we have identified the operability of mobile Agents in a protected network environment

Comparative Study of Microwave-assisted and Conventional Synthesis of 3-[1-(s-phenylimino) Ethyl]-2H-chromen-2-ones and Selected Hydrazone Derivatives

In this study, 3-acetylcoumarin 1, used as the essential precursor was synthesized by the reaction of salicyaldehyde with ethyl acetoacetate in the presence of a catalytic amount of piperidine in solvent-free medium. Schiff bases 2-9 were obtained by the condensation reaction of 3-acetylcoumarin, 1 with various aniline derivatives while reaction of 3-hydrazinoquinoxalin-2-one with four different 6-susbtituted 3-acetylcoumarins afforded the corresponding hydrazones 10-13. Both Schiff bases and hydrazone products were synthesized under microwave irradiation method and conventional synthetic strategy for comparative study. The microwave assisted reaction was remarkably successful and gave both Schiff bases and hydrazones in higher yields at shorter reaction time compared to conventional heating method. The characterization of the synthesized compounds were structurally confirmed by analytical data as well as spectroscopic means which involved 1H-and 13C-nmr, ir, UV-visible and mass spectra

AN INVESTIGATION OF THE EFFECTS OF POOR SPECIFICATION ON BUILDING COLLAPSE IN NIGERIA

This paper examines the effects of specification on building collapse in Nigeria. The study became necessary due to the ugly cases of buildings collapsing in the country over the years. In doing so, the study begins with review of relevant literature on the concept of specification, as well as the factors associated with building collapse. The need for specification in building construction projects was enunciated upon. Other factors that culminate in building collapse, such as load types; man-power; technical skills, etc. are discussed herein. The study further examines identifies and documents cases of building collapse in Nigeria to identify the causes and factors responsible for the collapse. Interviews were conducted with practicing professionals in the construction industry. This was done to obtain professional insights and experiences used as part of the data in the research. Findings from this study highlights consequential role of poor specification in causing building collapse, loss of lives and properties. This paper concludes with identifying the relevance of specification in ensuring adherence to appropriate materials and construction methods for structural stability. Recommendations are given to guard against poor specifications that result in the collapse of buildings, properties and ultimately loss of lives

OPTIMIZATION OF PECTINASE PRODUCTION BY ASPERGILLUS NIGER USING CENTRAL COMPOSITE DESIGN

Pectinases are a group of enzymes that catalyze the breakdown of pectin. Pectinase producing Aspergillus niger was obtained from a five-day old Eba (Cassava flakes). Response surface methodology was used for optimizing the process of the pectinase produced. Four independent variables which are, temperature, pH, substrate concentration and time of Heating at 70oC were used to optimize the significant correlation between the effects of the variables on pectinase production. A second-order polynomial was fitted to data and validated by ANOVA. The results revealed maximum pectinase production at pH 6.0, 50oC Temperature, 0.02% substrate concentration and the enzyme lost all its activity within 7 min of heating at 70oC. The study revealed that optimization of pectinase through RSM could improve the enzymatic characteristics and yield of the enzyme. The models used were highly significant with a correlation coefficient (R2) of 0.90

Genomic characterisation of human monkeypox virus in Nigeria

Monkeypox virus (MPXV) is a large, double-stranded DNA virus belonging to the Orthopox genus in the family Poxviridae. First identified in 1958, MPXV has caused sporadic human outbreaks in central and west Africa, with a mortality rate between 1% and 10%.1 Viral genomes from west Africa and the Congo Basin separate into two clades, the latter being more virulent.2 Recently, MPXV outbreaks have occurred in Sudan (2005), the Republic of the Congo and Democratic Republic of the Congo (2009), and the Central African Republic (2016).3 A suspected outbreak of human MPXV was reported to WHO on Sept 26, 2017, by the Nigeria Centre for Disease Control (NCDC) after a cluster of suspected cases had occurred in Yenagoa Local Government Area, Bayelsa State, Nigeria.4 Since the onset of the outbreak, 155 cases have been reported by the NCDC, of which 56 were confirmed.4 A subset of these samples was sent to the WHO Collaborating Center at the Institut Pasteur de Dakar (IPD) in Senegal for confirmation by PCR

AN INVESTIGATION OF THE EFFECTS OF POOR SPECIFICATION ON BUILDING COLLAPSE IN NIGERIA

This paper examines the effects of specification on building collapse in Nigeria. The study became necessary due to the ugly cases of buildings collapsing in the country over the years. In doing so, the study begins with review of relevant literature on the concept of specification, as well as the factors associated with building collapse. The need for specification in building construction projects was enunciated upon. Other factors that culminate in building collapse, such as load types; man-power; technical skills, etc. are discussed herein. The study further examines identifies and documents cases of building collapse in Nigeria to identify the causes and factors responsible for the collapse. Interviews were conducted with practicing professionals in the construction industry. This was done to obtain professional insights and experiences used as part of the data in the research. Findings from this study highlights consequential role of poor specification in causing building collapse, loss of lives and properties. This paper concludes with identifying the relevance of specification in ensuring adherence to appropriate materials and construction methods for structural stability. Recommendations are given to guard against poor specifications that result in the collapse of buildings, properties and ultimately loss of lives

Outcome After Surgical Stabilization of Rib Fractures Versus Nonoperative Treatment in Patients With Multiple Rib Fractures and Moderate to Severe Traumatic Brain Injury (CWIS-TBI)

BACKGROUND Outcomes after surgical stabilization of rib fractures (SSRF) have not been studied in patients with multiple rib fractures and traumatic brain injury (TBI). We hypothesized that SSRF, as compared with nonoperative management, is associated with favorable outcomes in patients with TBI. METHODS A multicenter, retrospective cohort study was performed in patients with rib fractures and TBI between January 2012 and July 2019. Patients who underwent SSRF were compared to those managed nonoperatively. The primary outcome was mechanical ventilation-free days. Secondary outcomes were intensive care unit length of stay and hospital length of stay, tracheostomy, occurrence of complications, neurologic outcome, and mortality. Patients were further stratified into moderate (GCS score, 9–12) and severe (GCS score, ≤8) TBI. RESULTS The study cohort consisted of 456 patients of which 111 (24.3%) underwent SSRF. The SSRF was performed at a median of 3 days, and SSRF-related complication rate was 3.6%. In multivariable analyses, there was no difference in mechanical ventilation-free days between the SSRF and nonoperative groups. The odds of developing pneumonia (odds ratio [OR], 0.59; 95% confidence interval [95% CI], 0.38–0.98; p = 0.043) and 30-day mortality (OR, 0.32; 95% CI, 0.11–0.91; p = 0.032) were significantly lower in the SSRF group. Patients with moderate TBI had similar outcome in both groups. In patients with severe TBI, the odds of 30-day mortality was significantly lower after SSRF (OR, 0.19; 95% CI, 0.04–0.88; p = 0.034). CONCLUSION In patients with multiple rib fractures and TBI, the mechanical ventilation-free days did not differ between the two treatment groups. In addition, SSRF was associated with a significantly lower risk of pneumonia and 30-day mortality. In patients with moderate TBI, outcome was similar. In patients with severe TBI a lower 30-day mortality was observed. There was a low SSRF-related complication risk. These data suggest a potential role for SSRF in select patients with TBI. LEVEL OF EVIDENCE Therapeutic, level IV

Cross-sectional and prospective associations between sleep, screen time, active school travel, sports/exercise participation and physical activity in children and adolescents

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