NIH STRATEGIC PLAN FOR AIDS RESEARCH RELATED TO RACIAL AND ETHNIC MINORITIES

OAR has established a unique and effective model for developing a consensus on scientific priorities for the annual comprehensive NIH Plan for HIV-Related Research. To develop the FY 2003 Plan, OAR sponsored a series of Planning Workshops to seek the input of non-NIH experts, including scientists from academia, foundations, and industry, and community representatives. These experts participated with NIH scientific and program staff in Planning Groups for Natural History and Epidemiology; Etiology and Pathogenesis; Therapeutics; Vaccines; Behavioral and Social Science; Microbicides; HIV Prevention Research; Racial and Ethnic Minorities; Women and Girls and HIV/AIDS Research and International Research Priorities. A list of participants in the Planning Group for Research Related to Racial and Ethnic Minorities is found in Appendix B. Participants in each Planning Group were asked to review and revise the objectives and strategies of the draft Plan, based on the state of the science, and to identify a set of priorities for their area. All groups were asked to address needs in the areas of information dissemination, training, infrastructure and capacity building related to their area. The resulting draft Plan was then provided to each Institute and Center Director and AIDS Coordinator for recommendations and comments. Finally, the Plan was reviewed by the Office of AIDS Research Advisory Council

University of Johannesburg HIV & AIDS report, 2011 & 2012

In the next decade UJ will position itself as a modern African city university, which is cosmopolitan in character, and asserts academic freedom in the liberal, progressive and transformative values it espouses. It will provide education that is affordable and accessible, that is challenging, imaginative and innovative, and contributes to a just, responsible and sustainable society. It will offer a comprehensive range of excellent programmes and will cultivate students with integrity, who are knowledgeable, well balanced and ethical and global citizens. In keeping with this vision, the HIV and AIDS Committee will achieve and implement a coordinated, comprehensive and integrated response in mitigating and managing the effects of the HIV and AIDS epidemic, based on four of UJ’s strategic thrusts

University of Johannesburg HIV & AIDS report, 2009 & 2010

In the next decade UJ will position itself as a modern African city university, which is cosmopolitan in character, and asserts academic freedom in the liberal, progressive and transformative values it espouses. It will provide education that is affordable and accessible, that is challenging, imaginative and innovative, and contributes to a just, responsible and sustainable society. It will offer a comprehensive range of excellent programmes and will cultivate students with integrity, who are knowledgeable, well balanced and ethical and global citizens. In keeping with this vision, the HIV and AIDS Committee will achieve and implement a coordinated, comprehensive and integrated response in mitigating and managing the effects of the HIV and AIDS epidemic, based on four of UJ’s strategic thrusts

Sexual and reproductive health and HIV in border districts affected by migration and poverty in Tanzania

Objectives To assess HIV knowledge, attitudes, sexual practices and sexual and reproductive health ( SRH) service delivery in border areas of Tanzania, with a view to support the prioritisation of SRH interventions in border areas. Methods The target sample comprised randomly selected people living near the border, aged 15 to 49 years. To gather information, we utilised: (i) a standardised questionnaire (n = 86; 42 men and 44 women) previously used in national household surveys conducted by the Tanzanian government; (ii) focus group discussions (ten male groupsn = 47; ten female groups, n = 51); and (iii) semi- structured interviews with service providers (n = 37). Results The mean number of sexual partners, frequency of multiple concurrent partnerships and engagement in transactional sex were significantly higher in the border community than in the national population. Knowledge about HIV was comparable with that in the general population. Access to SRH services was limited in the border areas. Conclusion Efforts to reduce HIV transmission and to improve SRH in the border areas should focus on gaps in service delivery rather than education and information activities alone. In addition, multi-sectorial efforts spanning the health, social, legal and private sectors addressing gender imbalances and poverty alleviation are imperative for reducing poverty-driven unsafe transactional sex

Analysis of the Prevention of Mother-to-Child Transmission (PMTCT) Service utilization in Ethiopia: 2006-2010

<p>Abstract</p> <p>Introduction</p> <p>Although progressive improvements have been made in the coverage and quality of prevention of HIV/AIDS mother-to-child transmission (PMTCT) services in Ethiopia, the national coverage remained persistently low. Analysis of the cascaded PMTCT services can reveal the advancements made and the biggest hurdles faced during implementation.</p> <p>Objective</p> <p>To examine the progresses and unaddressed needs in access and utilization of PMTCT services in Ethiopia from 2006 to 2010 thereby developing best-fit regression models to predict the values of key PMTCT indicators at critical future points.</p> <p>Methods</p> <p>Five-year national level PMTCT data were analyzed in a cascaded manner. Five levels of analysis were used for ten major PMTCT indicators. These included description of progress made, assessment of unaddressed needs, developing best-fit models, prediction for future points and estimation using constant prevalence. Findings were presented using numerical and graphic summaries.</p> <p>Results</p> <p>Based on the current trend, Ethiopia could achieve universal ANC coverage by 2015. The prevalence of HIV at PMTCT sites has shown a four-fold decrease during the five-year period. This study has found that only 53% of known HIV-positive mothers and 48% of known HIV-exposed infants have received ARV prophylaxis. Based on assumption of constant HIV prevalence, the estimated ARV coverage was found to be 11.6% for HIV positive mothers and 8.4% for their babies.</p> <p>Conclusion</p> <p>There has been a remarkable improvement in the potential coverage of PMTCT services due to rapid increase in the number of PMTCT service outlets. However, the actual coverage remained low. Integration of PMTCT services with grassroots level health systems could unravel the problem.</p

Reviewing progress: 7 Year Trends in Characteristics of Adults and Children Enrolled at HIV Care and Treatment Clinics in the United Republic of Tanzania.

To evaluate the on-going scale-up of HIV programs, we assessed trends in patient characteristics at enrolment and ART initiation over 7 years of implementation. Data were from Optimal Models, a prospective open cohort study of HIV-infected (HIV+) adults (>=15 years) and children (<15 years) enrolled from January 2005 to December 2011 at 44 HIV clinics in 3 regions of mainland Tanzania (Kagera, Kigoma, Pwani) and Zanzibar. Comparative statistics for trends in characteristics of patients enrolled in 2005--2007, 2008--2009 and 2010--2011 were examined. Overall 62,801 HIV+ patients were enrolled: 58,102(92.5%) adults, (66.5% female); 4,699(7.5%) children.Among adults, pregnant women enrolment increased: 6.8%, 2005--2007; 12.1%, 2008--2009; 17.2%, 2010--2011; as did entry into care from prevention of mother-to-child HIV transmission (PMTCT) programs: 6.6%, 2005--2007; 9.5%, 2008--2009; 12.6%, 2010--2011. WHO stage IV at enrolment declined: 27.1%, 2005--2007; 20.2%, 2008--2009; 11.1% 2010--2011. Of the 42.5% and 29.5% with CD4+ data at enrolment and ART initiation respectively, median CD4+ count increased: 210cells/muL, 2005--2007; 262cells/muL, 2008--2009; 266cells/muL 2010--2011; but median CD4+ at ART initiation did not change (148cells/muL overall). Stavudine initiation declined: 84.9%, 2005--2007; 43.1%, 2008--2009; 19.7%, 2010--2011.Among children, median age (years) at enrolment decreased from 6.1(IQR:2.7-10.0) in 2005--2007 to 4.8(IQR:1.9-8.6) in 2008--2009, and 4.1(IQR:1.5-8.1) in 2010--2011 and children <24 months increased from 18.5% to 26.1% and 31.5% respectively. Entry from PMTCT was 7.0%, 2005--2007; 10.7%, 2008--2009; 15.0%, 2010--2011. WHO stage IV at enrolment declined from 22.9%, 2005--2007, to 18.3%, 2008--2009 to 13.9%, 2010--2011. Proportion initiating stavudine was 39.8% 2005--2007; 39.5%, 2008--2009; 26.1%, 2010--2011. Median age at ART initiation also declined significantly. Over time, the proportion of pregnant women and of adults and children enrolled from PMTCT programs increased. There was a decline in adults and children with advanced HIV disease at enrolment and initiation of stavudine. Pediatric age at enrolment and ART initiation declined. Results suggest HIV program maturation from an emergency response