The tails in the Helix Nebula NGC 7293

We have examined a stream-source model for the production of the cometary tails observed in the Helix Nebula NGC 7293 in which a transonic or moderately supersonic stream of ionized gas overruns a source of ionized gas. Hydrodynamic calculations reveal velocity structures which are in good agreement with the observational data on tail velocities and are consistent with observations of the nebular structure. The results also are indicative of a stellar atmosphere origin for the cometary globules. Tail remnants persist for timescales long enough for their identification with faint striations visible in the nebula gas to be plausible.Comment: 7 pages, 6 figures, accepted for publication in A&

Giving patients granular control of personal health information: Using an ethics ‘Points to Consider’ to inform informatics system designers

Objective: There are benefits and risks of giving patients more granular control of their personal health information in electronic health record (EHR) systems. When designing EHR systems and policies, informaticists and system developers must balance these benefits and risks. Ethical considerations should be an explicit part of this balancing. Our objective was to develop a structured ethics framework to accomplish this. Methods: We reviewed existing literature on the ethical and policy issues, developed an ethics framework called a “Points to Consider” (P2C) document, and convened a national expert panel to review and critique the P2C. Results: We developed the P2C to aid informaticists designing an advanced query tool for an electronic health record (EHR) system in Indianapolis. The P2C consists of six questions (“Points”) that frame important ethical issues, apply accepted principles of bioethics and Fair Information Practices, comment on how questions might be answered, and address implications for patient care. Discussion: The P2C is intended to clarify whatis at stake when designers try to accommodate potentially competing ethical commitments and logistical realities. The P2C was developed to guide informaticists who were designing a query tool in an existing EHR that would permit patient granular control. While consideration of ethical issues is coming to the forefront of medical informatics design and development practices, more reflection is needed to facilitate optimal collaboration between designers and ethicists. This report contributes to that discussion

An agent-based model contrasts opposite effects of dynamic and stable microtubules on cleavage furrow positioning

From experiments by Foe and von Dassow (Foe, V.E., and G. von Dassow. 2008. J. Cell Biol. 183:457–470) and others, we infer a molecular mechanism for positioning the cleavage furrow during cytokinesis. Computer simulations reveal how this mechanism depends on quantitative motor-behavior details and explore how robustly this mechanism succeeds across a range of cell sizes

A study of a collection of fossil plants from the Lower Bagshot pipe-clay of Poole District Dorset. With a critical examination of the value of the epidermis in the determination of angiospermous plants

In a study of the records of J.S. Gardner and others, it is evident that the Hampshire Basin has yielded a quantity and variety of plants of Lower Bagshot age. The fossil flora, named from leaf-form and venation only, is generally described as indicating a sub-tropical climate, and is compared (by Gardner) with plants now living in parts of sub-tropical Australia. A few localities, such as Studland and Corfe Castle, in the Dorset part of the Hampshire Basin, are recorded as having an especially luxuriant flora, and it was in order to apply modern technique to some of these plant remains that the research was commenced. The first part of this paper, therefore, gives an account of the collecting of fossil material from the area around these two centres and of the extension of collecting to all the Pipe-Clay region in the immediate neighbourhood of Poole Harbour. The method, commonly in use at the present day for the naming of plants of Tertiary age, consisting in combining the external plant characters of form and venation with the microscopic epidermal characters, is tried and found to give no satisfactory results. The criticism of this method forms the subject matter of the second part of the paper.<p

The Color-Magnitude Relation in Coma: Clues to the Age and Metallicity of Cluster Populations

We have observed three fields of the Coma cluster of galaxies with a narrow band (modified Stromgren) filter system. Observed galaxies include 31 in the vicinity of NGC 4889, 48 near NGC 4874, and 60 near NGC 4839 complete to M_5500=-18 in all three subclusters. Spectrophotometric classification finds all three subclusters of Coma to be dominated by red, E type (ellipticals/S0's) galaxies with a mean blue fraction, f_B, of 0.10. The blue fraction increases to fainter luminosities, possible remnants of dwarf starburst population or the effects of dynamical friction removing bright, blue galaxies from the cluster population by mergers. We find the color-magnitude (CM) relation to be well defined and linear over the range of M_5500=-13 to -22. After calibration to multi-metallicity models, bright ellipticals are found to have luminosity weighted mean [Fe/H] values between -0.5 and +0.5, whereas low luminosity ellipticals have [Fe/H] values ranging from -2 to solar. The lack of CM relation in our continuum color suggests that a systematic age effect cancels the metallicity effects in this bandpass. This is confirmed with our age index which finds a weak correlation between luminosity and mean stellar age in ellipticals such that the stellar populations of bright ellipticals are 2 to 3 Gyrs younger than low luminosity ellipticals.Comment: 26 pages AAS LaTeX, 6 figures, accepted for publication in A

Pressure Modulator Radiometer (PMR) tests

The pressure modulator technique was evaluated for monitoring pollutant gases in the Earth's atmosphere of altitude levels corresponding to the mid and lower troposphere. Using an experimental set up and a 110 cm sample cell, pressure modulator output signals resulting from a range of gas concentrations in the sample cell were examined. Then a 20 cm sample cell was modified so that trace gas properties in the atmosphere could be simulated in the laboratory. These gas properties were measured using an infrared sensor

Assessing Errors Inherent in OCT-Derived Macular Thickness Maps

SD-OCT has become an essential tool for evaluating macular pathology; however several aspects of data collection and analysis affect the accuracy of retinal thickness measurements. Here we evaluated sampling density, scan centering, and axial length compensation as factors affecting the accuracy of macular thickness maps. Forty-three patients with various retinal pathologies and 113 normal subjects were imaged using Cirrus HD-OCT. Reduced B-scan density was associated with increased interpolation error in ETDRS macular thickness plots. Correcting for individual differences in axial length revealed modest errors in retinal thickness maps, while more pronounced errors were observed when the ETDRS plot was not positioned at the center of the fovea (which can occur as a result of errant fixation). Cumulative error can exceed hundreds of microns, even under “ideal observer” conditions. This preventable error is particularly relevant when attempting to compare macular thickness maps to normative databases or measuring the area or volume of retinal features

Points to consider in ethically constructing patient-controlled electronic health records

Patient advocates and leaders in informatics have long proposed that patients should have greater ability to control the information in their electronic health record (EHR), including how it can be accessed by their health care providers. The value of such “granular” control, as it has been termed, has been supported prominently in an influential report by the President’s Council of Advisors on Science and Technology (PCAST). Recently, the U.S. Department of Health and Human Services (HHS) Office of the National Coordinator for Health Information Technology (ONC) funded several projects to study key components of EHR systems, including exploring ways to allow granular control. This “Points to Consider” document provides an overview of the benefits, risks and challenges of granular control of EHRs; a review of the key ethical principles, values, and Fair Information Practices that ought to guide development of an EHR that accommodates granular control, and seven detailed Points to Consider to guide decision making.Award No: 90HT0054/01, a cooperative agreement program from the US Department of Health and Human Services, Office of the National Coordinator for Health IT to Indiana Health Information Technology, Inc. (IHIT) under the State HIE – Challenge Grant Program to the Indiana University School of Medicine and Regenstrief Institute, Inc

Dynamics and Thermodynamics of Systems with Long Range Interactions: an Introduction

We review theoretical results obtained recently in the framework of statistical mechanics to study systems with long range forces. This fundamental and methodological study leads us to consider the different domains of applications in a trans-disciplinary perspective (astrophysics, nuclear physics, plasmas physics, metallic clusters, hydrodynamics,...) with a special emphasis on Bose-Einstein condensates.Comment: Chapter of the forthcoming "Lecture Notes in Physics" volume: ``Dynamics and Thermodynamics of Systems with Long Range Interactions'', T. Dauxois, S. Ruffo, E. Arimondo, M. Wilkens Eds., Lecture Notes in Physics Vol. 602, Springer (2002). (see http://link.springer.de/series/lnpp/