The genetic ancestry of American Creole cattle inferred from uniparental and autosomal genetic markers

Cattle imported from the Iberian Peninsula spread throughout America in the early years of discovery and colonization to originate Creole breeds, which adapted to a wide diversity of environments and later received influences from other origins, including zebu cattle in more recent years. We analyzed uniparental genetic markers and autosomal microsatellites in DNA samples from 114 cattle breeds distributed worldwide, including 40 Creole breeds representing the whole American continent, and samples from the Iberian Peninsula, British islands, Continental Europe, Africa and American zebu. We show that Creole breeds differ considerably from each other, and most have their own identity or group with others from neighboring regions. Results with mtDNA indicate that T1c-lineages are rare in Iberia but common in Africa and are well represented in Creoles from Brazil and Colombia, lending support to a direct African influence on Creoles. This is reinforced by the sharing of a unique Y-haplotype between cattle from Mozambique and Creoles from Argentina. Autosomal microsatellites indicate that Creoles occupy an intermediate position between African and European breeds, and some Creoles show a clear Iberian signature. Our results confirm the mixed ancestry of American Creole cattle and the role that African cattle have played in their development

The genetic ancestry of american creole cattle inferred from uniparental and autosomal genetic markers.

Cattle imported from the Iberian Peninsula spread throughout America in the early years of discovery and colonization to originate Creole breeds, which adapted to a wide diversity of environments and later received influences from other origins, including zebu cattle in more recent years. We analyzed uniparental genetic markers and autosomal microsatellites in DNA samples from 114 cattle breeds distributed worldwide, including 40 Creole breeds representing the whole American continent, and samples from the Iberian Peninsula, British islands, Continental Europe, Africa and American zebu. We show that Creole breeds differ considerably from each other, and most have their own identity or group with others from neighboring regions. Results with mtDNA indicate that T1c-lineages are rare in Iberia but common in Africa and are well represented in Creoles from Brazil and Colombia, lending support to a direct African influence on Creoles. This is reinforced by the sharing of a unique Y-haplotype between cattle from Mozambique and Creoles from Argentina. Autosomal microsatellites indicate that Creoles occupy an intermediate position between African and European breeds, and some Creoles show a clear Iberian signature. Our results confirm the mixed ancestry of American Creole cattle and the role that African cattle have played in their development

La capacitación para el mejoramiento del desempeño profesional de los especialistas en gestión de los recursos humanos de las organizaciones empresariales

The present article seeks to base the process of specialists' training in administration of the Human resources for the improvement of its professional acting in the Managerial Organizations in Pinegrove of the River. As process of formative, permanent, systemic, flexible character and contextualized, for the sake of the appropriation of knowledge, abilities and these specialists' values that allow him professionally to be more competitive rising. They are revealed relating theoretical important from the consultation bibliography valorativa related with the current social historical context of the training.El presente artículo pretende fundamentar el proceso de capacitación de especialistas en gestión de los Recursos Humanos para el mejoramiento de su desempeño profesional en las Organizaciones Empresariales en Pinar del Río. Como proceso de carácter formativo, permanente, sistémico, flexible y contextualizado, en aras de elevar la apropiación de conocimientos, habilidades y valores de estos especialistas que le permitan ser más competitivos profesionalmente. Se revelan referentes teóricos importantes desde la consulta valorativa de bibliografía relacionada con el contexto histórico social actual de la capacitación

Selectividad de especies arbóreas por búfalos en pastoreo

Se realizó este estudio con el objetivo de medir la selectividad de los búfalos sobre especies arbóreas en pastoreo. Se utilizó un diseño totalmente aleatorizado con ocho repeticiones por accesión. Se realizaron dos pastoreos por época (inicio y mediados de cada una). Se determinó, mediante una escala del I al III, cuáles eran las especies altamente (III), medianamente (II) y no ramoneadas (I) que existían en cada época. El pasto predominante fue Megathyrsus maximus. Para el análisis de los resultados se empleó el análisis de conglomerados (análisis de Cluster). Las especies altamente ramoneadas para los dos períodos fueron: L. leucocephala, L. macrophylla CIAT-17240, B. purpurea, A. lebbeck, G. sepium, E. cyclocarpum, M. nigra, E. berteruana; las medianamente ramoneadas: A. kalkora, A. caribaea, A. lucida, A. odoratissima, A. berteriana, B. variegata var. candida, B. variegata, B. malabarica, Bauhinia sp., E. contortisiliquum, G. arborea, L. latisiliquum, P. discolor; y no fueron ramoneadas: A. semani, A. procera, B. reticulata, C. festuca, M. oleifera, C. sappan, C. festuca x C. nodosa, S. saman y Schizolobium sp. Se concluye que los búfalos mostraron preferencia por ramonear las accesiones de L. leucocephala, A. lebbeck, G. sepium, M. nigra, E. berteroana, E. cyclocarpum yB. purpurea, mientras que los contenidos de MS, FB y PB de la biomasa comestible de estas plantas sufrieron poca variación en sus valores por el efecto de la época, tendencia que se comprobó también para los minerales. Las accesiones ramoneadas demostraron ser una importante alternativa para la alimentación de esta especie por sus altos contenidos de proteína bruta y aceptabilidad

Asociación entre las variaciones climáticas y los casos de dengue en un hospital de Caracas, Venezuela, 1998-2004

Objetivos: Demostrar la presencia de asociación entre las variaciones climáticas (variables macro y microclimáticas) con los casos de dengue en el Hospital Pérez de León (HPL) de Caracas, Venezuela, en el período 1998-2004. Materiales y métodos: Se recolectó el registro mensual de los casos confirmados de dengue del Servicio de Epidemiología del HPL. Los datos microclimáticos se obtuvieron del Servicio de Meteorología de la Fuerza Aérea Venezolana, las precipitaciones se expresaron en mm de lluvia al mes y la temperatura máxima y mínima extrema de cada mes. Se usaron como índices climáticos el NAO, SOI, ONI de acuerdo con la clasificación de la NOAA, se clasificó en años El Niño y No El Niño (neutrales y La Niña). Para encontrar las asociaciones se usaron modelos de regresión lineal. Resultados: Para el periodo estudiado se registraron un total de 2187 casos confirmados de dengue, media anual de 267,86 casos (±371,21). El 2000 fue el año con mayor número de casos (hasta 214 casos/ mes), correspondiendo climáticamente con el fenómeno de La Niña. Se observó mayor número de casos durante los años No El Niño (1999, 2000, 2001, 2004) (60,26% más que la media) en comparación con los años El Niño (1998, 2002, 2003) donde se observó disminución en comparación con la media (-67,56%) (c 2 =21,76; p<0,01). Los modelos de regresiones lineales encontraron significancia entre dengue y las anomalías en las precipitaciones de Caracas (r 2 =0,01199; F=4,635; p=0,0319) y con las temperaturas máximas de Caracas (r 2 =0,1345; F=59,37; p<0,0001). Conclusiones: Los resultados reflejan la influencia positiva que tienen las condiciones climáticas (precipitaciones, temperatura y presencia del fenómeno La Niña) sobre la epidemiología del dengue en el este de Caracas, reflejada en el ingreso de pacientes con esta enfermedad en el Hospital Pérez de León de Caracas

Implante percutáneo de células mononucleares de sangre periférica movilizadas con factor estimulante de colonias granulocíticas, en la osteoartrosis de rodilla. Primer caso comunicado en Cuba Percutaneous implantation of peripheral blood mononuclear cells mobilized with granulocyte colony stimulating factor in osteoarthritis of the knee. First case reported in Cuba

La enfermedad articular degenerativa, también conocida como osteoartrosis, afecta al 10 % de los adultos mayores de 60 años de edad. Se caracteriza principalmente por dolor de la articulación afectada, crepitación, rigidez matinal y limitación progresiva de los movimientos de esa articulación. Todo esto conduce a un desgaste parcial o completo del cartílago articular. El tratamiento de la osteoartrosis de la rodilla constituye un gran desafío. Los avances recientes en el uso de la medicina regenerativa sugieren que las células madre adultas pudieran representar una alternativa promisoria en el tratamiento de esta enfermedad. En una paciente femenina de 61 años de edad con osteoartrosis de la rodilla, se realizó el implante percutáneo de células mononucleares autólogas movilizadas a la sangre periférica mediante el factor estimulante de colonias granulocíticas, y se logró una rápida mejoría clínica y radiológica. Este resultado sugiere que el proceder empleado es un método factible, simple, seguro y menos costoso, para el tratamiento de las lesiones degenerativas articulares.<br>The degenerative joint disease, also known as osteoarthrosis affects to 10% of elderlies aged 60. It is mainly characterized by pain in the involved joint, crepitation, morning stiff and a progressive limitation of movement of that joint leading to a partial or total wear of articular cartilage. The treatment of the knee osteoarthrosis is a great challenge. The recent advances in use of regenerative medicine suggest that adult stem cells could represent a promisor alternative in the treatment of this entity. In a female patient aged 61 presenting with knee osteoarthrosis authors placed a percutaneous implant of autologous mononuclear cells mobilized to peripheral blood by granulocyte colony-stimulating factor achieving a fast clinical and radiological improvement. This result suggests that the procedure used is a feasible, simple, safe and less expensive method for treatment of articular degenerative lesions

Author Correction: The genetic ancestry of American Creole cattle inferred from uniparental and autosomal genetic markers (Scientific Reports, (2019), 9, 1, (11486), 10.1038/s41598-019-47636-0)

Correction to: Scientific Reports https ://doi.org/10.1038/s4159 8-019-47636 -0, published online 07 August 2019 This Article contains errors. The Acknowledgements section in this Article is incomplete, the funding source LISBOA-01-0145-FEDER-016647 is omitted, “This work was supported by Animal Breeding Consulting S.L., Córdoba, Spain. This work was partially funded by the Veterinary Genetics Laboratory, University of California, Davis, VELOGEN S.L., Madrid, Spain and by Grupo de Referencia A19-17R LAGENBIO from Gobierno de Aragon/Fondo Social Europeo. C.G. was supported by Fundação Nacional para a Ciência e a Tecnologia (FCT), Portugal, Investigador FCT Grant IF/00, 866/2014, and Project grant PTDC/CVTLIV/2827/2014 co-funded by COMPETE 2020 POCI-01-0145-FEDER-016647. The authors thank the collaboration of breeders, breed associations and “Red Iberoamericana Sobre la Conservacion de la Biodiversidad de Animales Domesticos Locales para el Desarollo Rural Sostenible (Red CONBIAND)” for the sharing of biological samples. Members of the CYTED XII-H and CONBIAND networks are thanked for valuable cooperation over the years. Authors thank Juan Antonio Pereira (FCV-UAGRM, Bolivia) and Olivier Hanotte for their support with sampling Criollo Yacumeño and Eastern Shorthorn Zebu respectively.” should read: “This work was supported by Animal Breeding Consulting S.L., Córdoba, Spain. This work was partially funded by the Veterinary Genetics Laboratory, University of California, Davis, VELOGEN S.L., Madrid, Spain and by Grupo de Referencia A19-17R LAGENBIO from Gobierno de Aragon/Fondo Social Europeo. C.G. was supported by Fundação Nacional para a Ciência e a Tecnologia (FCT), Portugal, Investigador FCT Grant IF/00, 866/2014, Project grant PTDC/CVTLIV/2827/2014 co-funded by COMPETE 2020 POCI-01-0145-FEDER-016647 and LISBOA-01-0145-FEDER-016647. The authors thank the collaboration of breeders, breed associations and “Red Iberoamericana Sobre la Conservacion de la Biodiversidad de Animales Domesticos Locales para el Desarollo Rural Sostenible (Red CONBIAND)” for the sharing of biological samples. Members of the CYTED XII-H and CONBIAND networks are thanked for valuable cooperation over the years. Authors thank Juan Antonio Pereira (FCV-UAGRM, Bolivia) and Olivier Hanotte for their support with sampling Criollo Yacumeño and Eastern Shorthorn Zebu, respectively.” In addition, a Data Availability section is not included in the article – it should appear as below: “Data availability STR data used in our analysis is available in the Dryad repository: https :; doi.org/10.5061/dryad .5dv41 ns43”

The genetic ancestry of American Creole cattle inferred from uniparental and autosomal genetic markers

Cattle imported from the Iberian Peninsula spread throughout America in the early years of discovery and colonization to originate Creole breeds, which adapted to a wide diversity of environments and later received infuences from other origins, including zebu cattle in more recent years. We analyzed uniparental genetic markers and autosomal microsatellites in DNA samples from 114 cattle breeds distributed worldwide, including 40 Creole breeds representing the whole American continent, and samples from the Iberian Peninsula, British islands, Continental Europe, Africa and American zebu. We show that Creole breeds difer considerably from each other, and most have their own identity or group with others from neighboring regions. Results with mtDNA indicate that T1c-lineages are rare in Iberia but common in Africa and are well represented in Creoles from Brazil and Colombia, lending support to a direct African infuence on Creoles. This is reinforced by the sharing of a unique Y-haplotype between cattle from Mozambique and Creoles from Argentina. Autosomal microsatellites indicate that Creoles occupy an intermediate position between African and European breeds, and some Creoles show a clear Iberian signature. Our results confrm the mixed ancestry of American Creole cattle and the role that African cattle have played in their development