Synthesis of hippuric acid in liver homogenate

The synthesis of hippuric acid from benaoic acid and glycine resembles in several respects the synthesis of a peptide bond. A CONH group is formed, it is a to a carboxyl group, and the free energy of its formation is of the same order of magnitude. The synthesis was demonstrated in liver and kidney slices of a number of animals; it is inhibited by 0.001 M KCN, which is in accord with the view that the necessary free energy is derived from an oxidation.(1

Weather radar for urban hydrological applications: lessons learnt and research needs identified from 4 pilot catchments in North-West Europe

International audienceThis study investigates the impact of rainfall estimates of different spatial resolutions on the hydraulic outputs of the models of four of the EU RainGain project’s pilot locations (the Cranbrook catchment (UK), the Herent catchment (Belgium), the Morée-Sausset catchment (France) and the Kralingen District (The Netherlands)). Two storm events, one convective and one stratiform, measured by a polarimetric X-band radar located in Cabauw (The Netherlands) were selected for analysis. The original radar estimates, at 100 m and 1 min resolutions, were aggregated to a spatial resolution of 1000 m. These estimates were then applied to the high-resolution semi-distributed hydraulic models of the four urban catchments, all of which have similar size (between 5 and 8 km2), but different morphological, hydrological and hydraulic characteristics. When doing so, methodologies for standardising rainfall inputs and making results comparable were implemented. The response of the different catchments to rainfall inputs of varying spatial resolution is analysed in the light of model configuration, catchment and storm characteristics. Rather surprisingly, the results show that for the two events under consideration the spatial resolution (i.e. 100 m vs 1000 m) of rainfall inputs does not have a significant influence on the outputs of urban drainage models. The present study will soon be extended to more storms as well as model structures and resolutions, with the final aim of identifying critical spatial-temporal resolutions for urban catchment modelling in relation to catchment and storm event characteristics

N.T. Wright and the Body-Soul Predicament: The Presumption of Duality in Ontological Holism

N.T. Wright has offered Christian philosophers a proposal where it is apparently possible to hold the belief in the intermediate state-resurrection of the body and an ontological holism in the same sense at the same time. I argue that this not only creates a basic contradiction in Wright’s ontological paradigm, but also it is not a coherent and tenable proposal despite the fact one might eventually find a potential solution to such a quandary

Radiation hardness of small-pitch 3D pixel sensors up to HL-LHC fluences

A new generation of 3D silicon pixel detectors with a small pixel size of 50$\times$50 and 25$\times$100 $\mu$m$^{2}$ is being developed for the HL-LHC tracker upgrades. The radiation hardness of such detectors was studied in beam tests after irradiation to HL-LHC fluences up to $1.4\times10^{16}$ n$_{\mathrm{eq}}$/cm$^2$. At this fluence, an operation voltage of only 100 V is needed to achieve 97% hit efficiency, with a power dissipation of 13 mW/cm$^2$ at -25$^{\circ}$C, considerably lower than for previous 3D sensor generations and planar sensors.Comment: 5 pages, 2 figures, Proceedings of TIPP 2017, Beijing (International Conference on The Technology and Instrumentation in Particle Physics 2017

Clustered Microcalcification Detection Using Optimized Difference of Gaussians

The objective of this thesis is to design an automated microcalcification detection system to be used as an aid in radiologic mammogram interpretation. This research proposes the following methodology for clustered microcalcification detection. First, preprocess the digitized film mammogram to reduce digitization noise. Second, spatially filter the image with a difference of Gaussians (DoG) kernel. To detect potential microcalcifications, segment the filtered image using global and local thresholding. Next, cluster and index these detections into regions of interest (ROIs). Identify ROIs on the digitized image (or hardcopy printout) for final radiologic diagnosis

Research on renewable energy project opposition selected for Environmental Law and Policy Annual Review Award

A publication co-authored by Indiana University Maurer School of Law Dean Christiana Ochoa and 2021 Law School alumna Kacey Cook has been selected to appear in the 17th edition of the Environmental Law and Policy Annual Review. “Deals in the Heartland: Renewable Energy Projects, Local Resistance, and How Law Can Help” was authored by Ochoa, Cook, and University of Minnesota Law School third-year student Hanna Weil and was published in January 2023 in the Minnesota Law Review

CATTLE/BEEF SUBSECTOR'S STRUCTURE AND COMPETITION UNDER FREE TRADE

Industrial Organization, International Relations/Trade,