Changes in the atmospheric circulation conditions and regional climatic characteristics in two remote regions since the mid-20th century

A meridional Northern Hemisphere (NH) circulation epoch, which began in 1957, is marked by changes in the temperature and precipitation regimes over southwest Russia and central USA depending on the occurrence of NH atmospheric circulation regimes. A classification scheme proposed in 1968, and studied later put forth 13 NH circulation types, fitting more broadly into four groups, two of which are more zonal type flows and two of which are more meridional flows. Using the results of a previous study that showed four distinct sub-periods during the 1957-2017 epoch, the temperature and precipitation regimes of both regions were studied across all seasons in order to characterize modern day climate variability and their suitability for vegetation growth. Then the Hydrologic Coefficient, which combined the temperature and precipitation variables, was briefly studied. The most optimal conditions for vegetation growth, positive temperature and precipitation anomalies, were noted during the period 1970-1980 for southwest Russia, which was dominated by an increasingly more zonal flow regime in the Belgorod region and NH in general. For the central USA, the HTC showed more ideal conditions for agriculture in recent years due to favorable precipitation occurrence. In southwest Russia, variable precipitation regimes were noted during the meridional flow periods, and with the increase in temperature (since 1998), these can adversely affect the hydrothermal characteristics of the growing season. Finally, a comparison of the 13 NH circulation types with several teleconnection indexes demonstrated the robustness of the NH flow regime classification scheme used here

An interactive procedure of a transverse beam matching and correction in INR Linac

An application package is developed to carry out an interactive procedure for a transverse beam matching and correction in INR Linac. The results of multiple beam profile measurements in several accelerator areas are used. The currents in steering coils are found to suppress the beam displacement. The gradients in quadrupole lenses are calculated to match the beam. This procedure is successfully used in accelerator tuning.Разработан пакет программ для проведения интерактивной процедуры поперечного согласования и коррекции пучка по результатам измерения профилей пучка на различных участках линейного ускорителя ИЯИ РАН. Определяются режимы включения корректирующих элементов для выведения пучка на ось ускорителя и градиенты полей квадрупольных линз для согласования пучка с фокусирующим каналом ускорителя. Разработанная процедура успешно используется при настройке режимов работы ускорителя.Розроблено пакет програм для проведення інтерактивної процедури поперечного узгодження і корекції пучка за результатами виміру профілів пучка на різних ділянках лінійного прискорювача ІЯД РАН. Визначаються режими включення коригувальних елементів для виведення пучка на вісь прискорювача і градієнти полів квадрупольних лінз для узгодження пучка з фокусуючим каналом прискорювача. Розроблена процедура успішно використається при настроюванні режимів роботи прискорювача

РЕДКИЙ СЛУЧАЙ СОЧЕТАННОЙ ПАТОЛОГИИ – АНОМАЛЬНЫЙ ДРЕНАЖ ПОРТАЛЬНОЙ СИСТЕМЫ В КОРОНАРНЫЙ СИНУС, ГИПОПЛАЗИЯ ПРАВОЙ ВЕТВИ ВОРОТНОЙ ВЕНЫ И ВЫСОКАЯ ЛЕГОЧНАЯ ГИПЕРТЕНЗИЯ

Aim: to present an exceptional case of the combined pathology – an abnormal drainage of portal system to the coronary sinus, hypoplasia of the right branch of the portal vein and high pulmonary hypertension. Materials and methods. The patient P. of 22 years old arrived at congenital heart diseases surgical unit of V.I. Shumakov Federal Research Center of Transplantology and Artifi cial Organs. After the examination he was diagnosed with congenital disease – abnormal confl uence of the portal vein in the right atrium. Insuffi ciency of the tricuspid valve 3–4. High pulmonary hypertension. Insuffi ciency of blood circulation of IIa, III functional class. After computer tomography there is no division of the portal vein. Vein is drained in the right atrium bypass with a diameter of 2,3 cm following from the portal vein to the coronary sinus. Results. Considering hopelessness of conservative therapy the only method of the radical help to the patient is two-stage surgical intervention – transplantation of a heart-pulmonary complex and liver transplantation. Conclusion. Presented rare clinical case demonstrates the combination of congenital anomalies of the portal system and the heart with high pulmonary hypertension, and is based on a functioning fetal venous duct (ductus venosus), bypassing the liver in the right atrium (coronary sinus) in combination with hypoplasia of the right portal vein.Цель: представить редкий случай сочетанной патологии – аномальный дренаж портальной системы в коронарный синус, гипоплазия правой ветви воротной вены и высокая легочная гипертензия. Материалы и методы. Пациент П. 22 лет поступил в отделение хирургии врожденных пороков сердца ФГБУ «ФНЦ трансплантологии и искусственных органов им. акад. В.И. Шумакова». После обследования поставлен диагноз «врожденный порок – аномалия впадения воротной вены в правое предсердие; недостаточность трехстворчатого клапана 3–4-й степени; высокая легочная гипертензия; недостаточность кровообращения IIa, III функциональный класс». По данным спиральной компьютерной томографии, отсутствует внyтрипеченочное деление воротной вены. Вена дренируется в правое предсердие посредством шунта диаметром 2,3 см следующего от воротной вены в коронарный синус. Результаты. Учитывая бесперспективность консервативной терапии, для пациента единственным методом радикальной помощи является двухэтапное хирургическое вмешательство – трансплантация сердечно-легочного комплекса и трансплантация печени. Заключение. Описанный редкий клинический случай демонстрирует сочетание врожденной аномалии портальной системы и сердца с высокой легочной гипертензией, в основе которого лежит функционирующий эмбриональный венозный проток (ductus venosus), шунтирующийся в обход печени в правое предсердие (коронарный синус), в сочетании с гипоплазией правой воротной вены

DIRECTIONS FOR THE RECOVERY OF AGRICULTURAL PRODUCTION ON RADIOACTIVELY CONTAMINATED LANDS

Effective management of agricultural production in the Polesie Ukraine traditionally was complicated through the low natural land fertility, their high acidity, perevolotsky valley. During the centrally planned economic system that the natural contrast of the Polesie land had been somewhat neglected by the state through differentiation of purchase prices for agricultural products, which gave the possibility of redistribution of the rent in favor of the farms with poorer land. With transition to market relations the role of the state, and hence the possibility of its influence on this situation has changed dramatically. Economic conditions have become more profitable for the farmers that are occupying the best lands. However, the situation in the regions has not yet been investigated systematically taking into account the modern complex socio-economic processes and phenomena caused by increased environmental stress on land resources. One of the most pernicious environmental effects of the Chernobyl accident was radioactive contamination of agricultural land, defined in the final stage of transfer of radionuclides in the human body and further irradiation. The main danger of the accumulation by plants of radionuclides lies in the fact that they are a major link in the migratory chain of transmission of radionuclides to the more radiosensitive species and, above all, human. Economic feature of agricultural production in the study area is insufficient pricesambien, transformation of land use, violations of industrial-economic relations, the structure of agricultural production, changes in the natural-cost structure commodity products, the reform of the organizational structure of agricultural production. In the farms located in contaminated areas, the necessary conversion of dairy cattle for meat. In conditions of high pollution, the production of milk requires a serious sanitary objections in that time, as meat production is more environmentally friendly. The suspension of activities and the provision of radioactively clean food products led to the growth of volumes of consumption of contaminated food of local production, the increase in the number of people exceeding the doses of internal irradiation and the deterioration of the health status of the people of radioactively contaminated territories. The main component of the mechanism by contaminated land is agricultural activities (placement of crops, depending on the ability to accumulate radionuclides, soil treatment), agrochemical activities (liming of acidic soils, application of mineral and organic fertilizers and the use of sorbents, change of mode of feeding of animals and processing of animal products to reduce the content of radionuclides. Of course, the above list of events is far from complete, this is only the basic that require mandatory implementation in agricultural production. Among the measures of rehabilitation of polluted areas leading place belongs to the radical improvement of meadows and pastures, which in turn requires a considerable amount of seeds of cereals and legumes. The analysis of economic efficiency of growing of the testes, including radioactively contaminated region shows that even in marginal soils of Polesye in low yield of the seed farms have substantial profits. On soils with acidity the most common and affordable event reduce radionuclide accumulation in products is liming, which not only reduces the accumulation of radionuclides in agricultural crops but also improves soil fertility, increases yield and contributes to the dilution of radionuclides per unit mass of crop production. Only a comprehensive use of differentiated areas of contaminated land will allow some measure to improve the ecological situation on the territory of the object

Influence informatively-wave therapies by a vehicle tuning «Fork» on the basic links of immune defence of organism.

The purpose of the real research was an estimation of action of vehicle tuning FORK on the basic links of immune defence of organism (phagocyter activity, cellular and humoral immunity) for patients. Under a supervision there were patients with different violations of the immune system in the sharp and chronic stage in complex therapy of internal illnesses. 27 patients took part in research. It is teenagers in age from 12 to 15 years. It is recommended to utillize informatively-wave therapy for the improvement of function of the immune system of organism, for defence and prophylaxis of different heterospecific somatopathies

Влияние холецистэктомии в молодом возрасте на течение метаболического синдрома у женщин

Rationale:  At present, the  metabolic  syndrome and  pathophysiology  of non-alcoholic  fatty  liver disease, as well as identification of factors that may  influence  the  rate  of development of dystrophy and fibrosis in the liver are in the focus of investigators'  attention. This study represents an attempt to  detail  metabolic  derangements and liver tissue  abnormalities  after  cholecystectomy in patients  with metabolic  syndrome  at baseline.Aim: To study  the  influence  of cholecystectomy performed  at younger  age on the course of metabolic syndrome in women.Materials and methods: This was a retrospective analytical study  in a sample  of 57 female  patients  with  metabolic syndrome (International Diabetes Federation criteria 2005) aged  from 18 to 44 years (young age according  to the World Health Organization definition). From those, 30 patients  with cholelithiasis were included  into the control group  and 27 patients  who  had  undergone  cholecystectomy in this age range were included into the comparison group. We analyzed  their past  history, results  of clinical examination, laboratory  tests, abdominal ultrasound  examination, esophagogastroduodenoscopy, hydrogen  respiration  test  with lactulose, as well as the results of needle  liver biopsy.Results: Non-alcoholic steatohepatitis after cholecystectomy was associated with the excessive bacterial growth  in the small intestine  (р = 0.026), ultrasound signs of cholangitis (р = 0.041), and diarrhea syndrome (р = 0.027). Liver fibrosis was significantly more frequent in association with chronic diarrhea  (р = 0.034)  and  past  clinical signs  of post-cholecystectomy syndrome (р = 0.044). There was a strong direct correlation between the grade of fibrosis and  the  time  since  cholecystectomy (r = 0.77; р = 0.047).Conclusion: Cholecystectomy performed  at young  age predicts  progression  of metabolic abnormalities  in women with metabolic syndrome.Актуальность. Сегодня в фокусе внимания исследователей находятся  такие  проблемы,  как метаболический синдром и процессы формирования неалкогольной жировой болезни печени, выявление факторов, влияющих на скорость развития дистрофических и фибротических изменений  в ткани печени.  Настоящее  исследование демонстрирует попытку более детального   изучения    метаболических    нарушений и состояния ткани печени в постхолецистэктомическом  периоде  у пациентов  с изначально регистрируемым метаболическим синдромом.Цель – изучить влияние холецистэктомии в молодом возрасте на течение метаболического синдрома у женщин.Материал и методы. Проведено ретроспективное аналитическое исследование. В выборку включены 57 пациенток с признаками  метаболического  синдрома (критерии IDF 2005 г.) в возрасте от 18 до 44 лет (молодой возраст согласно определению Всемирной    организации     здравоохранения). Из них 27  пациенток, страдающих  желчнокаменной болезнью, составили основную группу, 30  пациенток,  перенесших   холецистэктомию в этот возрастной  промежуток, вошли в группу сравнения. Проанализированы данные анамнеза, клинического обследования, лабораторные показатели, данные  ультразвукового  исследования органов брюшной полости, эзофагогастродуоденоскопии, водородного дыхательного  теста  с  лактулозой,  а  также  результаты пункционной биопсии печени.Результаты. Неалкогольный стеатогепатит в постхолецистэктомическом      периоде      ассоциирован с избыточным бактериальным ростом в тонкой кишке  (р = 0,026),  ультразвуковыми   признаками  холангита   (р = 0,041),  синдромом   диареи (р = 0,027). Фиброз статистически значимо чаще регистрировался в сочетании с хронической диареей   (р = 0,034)  и  клиническими  проявлениями  постхолецистэктомического   синдрома в анамнезе  (р = 0,044). Выявлена сильная  прямая корреляционная связь между степенью фиброза и длительностью постхолецистэктомического периода  (r = 0,77; р = 0,047).Заключение. Холецистэктомия в молодом возрасте является предиктором прогрессирования метаболических расстройств  у женщин с метаболическим синдромом