Psychological features of personal development of younger adolescents in the process of leisure activities

The article presents the results of analysis of younger adolescents’ psychological characteristics and provides a description of a comprehensive program created in order to ensure effective personal development of children in this age group in the process of carrying out leisure activities. To test the program, a sample was formed consisting of 60 adolescents studying at Municipal Budgetary General Education Institution “School No. 134” in Nizhny Novgorod. The results of the study indicate significant changes among all criteria analyzed for the experimental and the control groups. The scientific significance of the data obtained lies in the expansion of the idea of younger adolescents’ personal qualities’ multidimensionality and the opportunity provided to study the phenomenon in more detail. Indicators obtained during the course of the study can be used to organise extracurricular activities for adolescents, hold seminars and personal development trainings as well as develop methodological manuals on personality psychology

Evaluating the effectiveness of public health financing based on financial and non-financial indicators in terms of the knowledge economy

In conditions of the knowledge economy human capital, human value are the main factors of economic growth and prosperity of the state. Qualitative characteristics of human capital are indicators of public health. Therefore, one of the most important tasks of the state is to assess the effectiveness of financing public health expenditures. The methodological base of the research was the methods of system and economic analysis, mathematical statistics and decision optimization, which resulted in the identification of factors influencing the resource supply, availability and quality of public health. The formation of a comprehensive indicator of the effectiveness of the public health system based on the system of financial and non-financial indicators will allow to form numerically an assessment of the effectiveness of investments in public health and draw conclusions about the resources' provision, level of development, accessibility and quality of public health. The obtained results can be used in making effective public financial decisions, which allow to achieve an increase of accessibility and quality of health care, focusing on the human capital in conditions of knowledge economy.peer-reviewe

Study of acute and chronic toxicity of feed additive based on vermiculture

The paper presents the results of study of the toxicity of a feed additive, which includes Leuzea safflower (Rhaponticum carthamoides) and protein obtained from vermiculture. The acute toxicity of the feed additive was studied in 31 SD white rats. It has been established that the acute oral toxicity of the feed additive is above 2500 mg/kg, which makes it possible to classify the feed additive as hazard class 3 and classify it as “moderately hazardous” according to GOST 12.1.007-76. The chronic toxicity of the feed additive was studied in 22 SD white rats. The feed additive was administered orally at a dose of 120 and 1200 mg/kg for 30 days. Long-term effects were assessed 14 days after the last introduction of the feed additive. To assess the toxic effects, the effect of the additive on the general condition of the animals, food and water intake was evaluated, blood and urine were analyzed. Complete blood count was carried out by standard methods with the determination of the following parameters: hematocrit, hemoglobin level, the number of erythrocytes, platelets, leukocytes, eosinophils, segmented neutrophils, lymphocytes and monocytes. The study of biochemical parameters of blood was carried out using standard kits for biochemical analysis. The following indicators were determined: ALT, total bilirubin, glucose, creatinine and urea. The urinalysis included the determination of the following indicators: density, leukocytes, nitrites, pH, erythrocytes, protein,  glucose, ascorbic acid, ketones, urobilinogen, bilirubin. There was no statistically significant difference in blood and urine parameters between the animals of the control and experimental groups. A pathohistological examination of the stomach, liver, kidneys and heart was carried out, which showed the absence of a toxic effect of the feed additive. Local irritant action was studied in pathomorphological studies. It has been established that the feed additive does not have an irritating effect at the injection site. Thus, the feed additive can be used in feeding farm animals and birds at the recommended dose

Microstructure and properties of a silicon coating deposited on a titanium nickelide substrate using molecular-beam epitaxy equipment

The microstructure and properties of a silicon coating on a titanium nickelide substrate were studied to assess the possibility of using such a coating to improve the biocompatibility of medical implants. The silicon coating with thickness of 4.0±0.5 microns was applied to the TiNi substrate on a molecular beam epitaxy unit. The coating had a submicrocrystalline structure with a crystallite size of 0.1...0.2 microns, a developed surface, and high crack resistance

CHANGE OF NON-SPECIFIC FACTORS OF IMMUNITY UNDER INFLUENCE OF INTERFERON INDUCTOR (CYCLOFERON) IN BRONCHIAL ASTHMA IN CHILDREN

The aim of the work was to evaluate the effect of immunomodulation therapy on factors of nonspecific immunity in children with bronchial asthma (BA) by including interferon (cycloferon) in a standard therapy. 120 children with BA aged from 5 to 14 were examined. The main group (n = 60) included children who, in addition to basic therapy, received an interferon inducer (cycloferon) according to the generally accepted scheme. In comparison group were children who received only basic therapy (n = 60), depending on the severity of the disease. In control group were 25 healthy children. The level of serum interferon, virus-induced interferon production (VII), mitogen-stimulated production of interferon (MSI), phagocytic activity of neutrophils, as well as spontaneous and induced activity were determined. The arithmetic mean (M) and the absolute value error (m) were statistically calculated. The reliability of the differences was determined by the t-test of the Student (p < 0,05). The analysis of the indices of interferon status and phagocytic activity, depending on the type of therapeutic tactics, showed that as a result of the inclusion of cycloferon in the baseline, there was a significant increase in the levels of VII (p < 0,05) and MSI (p < 0,05 ), spontaneous and induced neutrophil activity. It was noted that this positive effect was more noticeable in moderate and severe BA (p < 0,05). Activation of factors of nonspecific protection contributed to a decrease in the frequency of exacerbations of BA in children, as well as a longer-term clinical remission in this contingent of children

Comparative study of melaphen and kinetin influence on the growth and energetic process of plant cells

The results obtained for the unicellular algae Chlorella vulgaris as an object indicate that synthetic preparation melaphen, like kinetin, participates in regulation of many physiological processes in plants. It is concluded from the data on unidirectional action of natural phytohormone kinetin and melaphen on the plant cell. However, their action mechanism can be not identical

The use of controlled balloon tamponade in an obstetric hospital

Obstetric haemorrhage is an important problem worldwide and is a frequent cause of maternal mortality. One of the conservative methods of treatment is a controlled balloon tamponade, which has shown its effectiveness when used. This work is to study the effectiveness of the use of UBT on the example of treatment of hypotonic bleeding in the Tyumen regional Perinatal center. The obtained results have allowed to draw a conclusion about high efficiency of use of this method.Акушерские кровотечения являются важной проблемой во всем мире, являясь частой причиной материнской смертности. Одним из консервативных способов лечения является управляемая баллонная тампонада, показавшая свою эффективность при использовании. Данная работа заключается в изучении эффективности использования УБТ на примере лечения гипотонических кровотечений в Тюменском областном Перинатальном центре. Полученнные результаты позволили сделать вывод о высокой эффективности использования данного метода

Особенности эксергетического анализа энергоресурсосберегающих систем водного хозяйства

The specific features of applying the exergy analysis method for the energy resource saving waterworks systems of industrial plants were considered. The analysis of the influence of changes in polluting substance mass loading value on changes in exergy value upon mixing water technological flows was carried out.Рассмотрены особенности применения метода эксергетического анализа энергоресурсо-сбе-регающих систем водного хозяйства промышленных предприятий. Проведен анализ влияния изменения величины массовой нагрузки по загрязняющему веществу на изменение значения эксергии при смешивании водных технологических потоков

Hopf algebras and Markov chains: Two examples and a theory

The operation of squaring (coproduct followed by product) in a combinatorial Hopf algebra is shown to induce a Markov chain in natural bases. Chains constructed in this way include widely studied methods of card shuffling, a natural "rock-breaking" process, and Markov chains on simplicial complexes. Many of these chains can be explictly diagonalized using the primitive elements of the algebra and the combinatorics of the free Lie algebra. For card shuffling, this gives an explicit description of the eigenvectors. For rock-breaking, an explicit description of the quasi-stationary distribution and sharp rates to absorption follow.Comment: 51 pages, 17 figures. (Typographical errors corrected. Further fixes will only appear on the version on Amy Pang's website, the arXiv version will not be updated.

The peculiarities of exergy analysis of energy-resource-saving water management systems

The specific features of applying the exergy analysis method for the energy resource saving waterworks systems of industrial plants were considered. The analysis of the influence of changes in polluting substance mass loading value on changes in exergy value upon mixing water technological flows was carried out