83 research outputs found
Relationship between Medication Use and Cardiovascular Disease Health Outcomes in the Jackson Heart Study
- Author
- Addison
- Brenda W. Jenkins
- Campbell-Jenkins
- Chisholm
- Chobanian
- Clifton C. Addison
- Cooper
- Cora Champion
- Cramer
- Daniel Sarpong
- Elsayed
- Gregory Wilson
- Ho
- Honda
- Hyre
- Jeraline Sims
- LaFleur
- McCullough
- McDonnell
- Monique S. White
- Munger
- Munger
- Osterberg
- Oâ Conner
- Pladevall
- Rasmussen
- Rosamond
- Safren
- Sajatovic
- Schroeder
- Senst
- Shenolikar
- Vrijens
- Publication venue
- Molecular Diversity Preservation International (MDPI)
- Publication date
- 01/06/2011
- Field of study
Even though some medications have the potential to slow the progress of atherosclerosis and development of CVD, there are many at-risk individuals who continue to resist the benefits that are available by not following the advice of medical professionals. Non-adherence to prescribed drug regimens is a pervasive medical problem that negatively affects treatment outcomes. Information from standardized interviews of 5301 African Americans participating in the Jackson Heart Study was examined to determine the association between demographic parameters, behavior including adherence to prescribed medical regimens, and health outcomes. Data were also collected at Annual Follow-Up and Surveillance visits. During the two weeks prior to the examination visit, almost 52% of the participants reported taking blood pressure medication, 14% took cholesterol medication, 16% took medication for diabetes, and 19% took blood thinning medication. Of those who did not take the prescribed medications, the reasons given were the following: 47% were in a hurry, too busy, or forgot to take medications; 23% were trying to do without medications; 18% had no money to purchase medications; 19% indicated that the medications made them feel bad; 17% felt that they could not carry out daily functions when taking medications. The African American population can benefit from heightened awareness of the risk factors that are associated with CVD and the benefits of following a prescribed treatment regimen. Unacceptable secondary effects of prescribed medication comprised an important cause of non-compliance. Encouragement of this population to communicate with their healthcare providers to ensure that medication regimens are better tolerated could increase compliance and improve health outcomes
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Ubiquitin sets the timer: impacts on aging and longevity
- Author
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2014
- Field of study
Protein homeostasis is essential for cellular function, organismal growth and viability. Damaged and aggregated proteins are turned over by two major proteolytic routes of the cellular quality-control pathways: the ubiquitin-proteasome system and autophagy. For both these pathways, ubiquitination provides the recognition signal for substrate selection. This Commentary discusses how ubiquitin-dependent proteolytic pathways are coordinated with stress- and aging-induced signals
Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)
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- Zhang Z.
- Zhao H.
- Zhao L.
- Zhao S.
- Zhao T.
- Zhao X. -F.
- Zhao Y.
- Zhao Y.
- Zhao Y.
- Zhao Y.
- Zheng G.
- Zheng K.
- Zheng L.
- Zheng S.
- Zheng X. -L.
- Zheng Y.
- Zheng Z. -G.
- Zhivotovsky B.
- Zhong Q.
- Zhou A.
- Zhou B.
- Zhou C.
- Zhou G.
- Zhou H.
- Zhou H.
- Zhou H.
- Zhou J.
- Zhou J.
- Zhou J.
- Zhou J.
- Zhou K.
- Zhou R.
- Zhou X. -J.
- Zhou Y.
- Zhou Y.
- Zhou Y.
- Zhou Z.
- Zhou Z. -Y.
- Zhu B.
- Zhu C.
- Zhu G. -Q.
- Zhu H.
- Zhu H.
- Zhu H.
- Zhu W. -G.
- Zhu Y.
- Zhu Y.
- Zhuang H.
- Zhuang X.
- Zientara-Rytter K.
- Zimmermann C. M.
- Ziviani E.
- Zoladek T.
- Zong W. -X.
- Zorov D. B.
- Zorzano A.
- Zou W.
- Zou Z.
- Zou Z.
- Zuryn S.
- Zwerschke W.
- Publication venue
- 'Informa UK Limited'
- Publication date
- 01/01/2021
- Field of study
Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1.
- Author
- Abdel-Aziz AK
- Abdelfatah S
- Abdellatif M
- Abdoli A
- Abel S
- Abeliovich H
- Abildgaard MH
- Abudu YP
- Acevedo-Arozena A
- Adamopoulos IE
- Adeli K
- Adolph TE
- Adornetto A
- Aflaki E
- Agam G
- Agarwal A
- Aggarwal BB
- Agnello M
- Agostinis P
- Agrewala JN
- Agrotis A
- Aguilar PV
- Ahmad ST
- Ahmed ZM
- Ahumada-Castro U
- Aits S
- Aizawa S
- Akkoc Y
- Akoumianaki T
- Akpinar HA
- Al-Abd AM
- Al-Akra L
- Al-Gharaibeh A
- Alaoui-Jamali MA
- Alberti S
- Alcocer-GĂłmez E
- Alessandri C
- Ali M
- Alim Al-Bari MA
- Aliwaini S
- Alizadeh J
- Almacellas E
- Almasan A
- Alonso A
- Alonso GD
- Altan-Bonnet N
- Altieri DC
- Alves da Costa C
- Alves S
- Alzaharna MM
- Amadio M
- Amantini C
- Amaral C
- Ambrosio S
- Amer AO
- Ammanathan V
- An Z
- Andersen SU
- Andrabi SA
- Andrade-Silva M
- Andres AM
- Angelini S
- Ann D
- Anozie UC
- Ansari MY
- Antas P
- Antebi A
- AntĂłn Z
- Anwar T
- Apetoh L
- Apostolova N
- Araki T
- Araki Y
- Arasaki K
- Araya J
- AraĂșjo WL
- Arden C
- Arguelles S
- Arias E
- Arikkath J
- Arimoto H
- Ariosa AR
- Armstrong-James D
- Arnauné-Pelloquin L
- Aroca A
- Arroyo DS
- Arsov I
- Artero R
- Arévalo M-A
- Asaro DML
- Aschner M
- Ashrafizadeh M
- Ashur-Fabian O
- Atanasov AG
- Au AK
- Auberger P
- Auner HW
- Aurelian L
- Autelli R
- Avagliano L
- Aveic S
- Aveleira CA
- Avin-Wittenberg T
- Aydin Y
- Ayton S
- Ayyadevara S
- Azzopardi M
- Baba M
- Backer JM
- Backues SK
- Bae D-H
- Bae O-N
- Bae SH
- Baehrecke EH
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- Baek SH
- Bagetta G
- Bagniewska-Zadworna A
- Bai H
- Bai J
- Bai X
- Bai Y
- Bairagi N
- Baksi S
- Balazadeh S
- Balbi T
- Baldari CT
- Balduini W
- Ballabio A
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- Bandopadhyay R
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- Baptista MS
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- Barlow PG
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- Barreto GE
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- Bartel B
- Bartolome A
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- Basagoudanavar SH
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- Beck GR
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- Behrens GMN
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- Besirli CG
- Besteiro S
- Betin VM
- Beyaert R
- Bezbradica JS
- Bhaskar K
- Bhatia-Kissova I
- Bhattacharya R
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- Bhuiyan MS
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- Boya P
- Bozhkov PV
- Bozi LHM
- Bozkurt TO
- Brackney DE
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- Brandts CH
- Braun RJ
- Braus GH
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- Bravo-San Pedro JM
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- Briones-Herrera A
- Broaddus VC
- Brodersen P
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- Brody SL
- Bronson PG
- Bronstein JM
- Brown CN
- Brown RE
- Brum PC
- Brumell JH
- Brunetti-Pierri N
- Bruno D
- Bryson-Richardson RJ
- Bucci C
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- Buchan JR
- Buchrieser C
- Buckingham EM
- Budak H
- Budini M
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- Buitrago-Molina LE
- Bultynck G
- Burada F
- Buraschi S
- Burgoyne JR
- BurĂłn MI
- Bustos V
- Butturini E
- Byrd A
- BĂĄnrĂ©ti Ă
- BĂŒttner S
- Cabas I
- Cabrera-Benitez S
- Cadwell K
- Cai J
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- Calbet JA
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- Caldwell KA
- Call JA
- Calvani R
- Calvo AC
- Calvo-Rubio Barrera M
- Camara NO
- Camonis JH
- Camougrand N
- Campanella M
- Campbell EM
- Campbell-Valois F-X
- Campello S
- Campesi I
- Campos JC
- Camuzard O
- Cancino J
- Candido de Almeida D
- Canesi L
- Caniggia I
- Canonico B
- CantĂ C
- Cao B
- Caraglia M
- Caramés B
- Carchman EH
- Cardenal-Muñoz E
- Cardenas C
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- Cardoso SM
- Carew JS
- Carle GF
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- Carmona-Gutierrez D
- Carneiro LA
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- Carosi JM
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- Carroll B
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- Carvalho AN
- Casanova M
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- Cassioli C
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- Castillo-Lluva S
- Castoldi F
- Castori M
- Castro AF
- Castro-Caldas M
- Castro-Hernandez J
- Castro-Obregon S
- Catz SD
- Cavadas C
- Cavaliere F
- Cavallini G
- Cavinato M
- Cayuela ML
- Cebollada Rica P
- Cecarini V
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- Cechowska-Pasko M
- Cenci S
- Ceperuelo-Mallafré V
- Cerqueira JJ
- Cerutti JM
- Cervia D
- Cetintas VB
- Cetrullo S
- Chae H-J
- Chagin AS
- Chai C-Y
- Chakrabarti G
- Chakrabarti O
- Chakraborty T
- Chakraborty T
- Chami M
- Chamilos G
- Chan DW
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- Chan EYW
- Chan H
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- Chan HYE
- Chan MTV
- Chan YS
- Chandra PK
- Chang C
- Chang C-P
- Chang H-C
- Chang K
- Chao J
- Chapman T
- Charlet-Berguerand N
- Chatterjee S
- Chaube SK
- Chaudhary A
- Chauhan S
- Chaum E
- Checler F
- Cheetham ME
- Chen C-S
- Chen G-C
- Chen J-F
- Chen L
- Chen L
- Chen LL
- Chen M
- Chen M-K
- Chen N
- Chen Q
- Chen R-H
- Chen S
- Chen W
- Chen W
- Chen X
- Chen X-M
- Chen X-W
- Chen Y
- Chen Y
- Chen Y
- Chen Y-G
- Chen Y-J
- Chen Y-Q
- Chen Z
- Chen Z
- Chen Z
- Chen Z-H
- Chen ZJ
- Chen ZS
- Cheng H
- Cheng J
- Cheng S-Y
- Cheng W
- Cheng X
- Cheng X-T
- Cheng Y
- Cheng Z
- Cheong H
- Cheong JK
- Chernyak BV
- Cherry S
- Cheung CFR
- Cheung CHA
- Cheung K-H
- Chevet E
- Chi RJ
- Chiang AKS
- Chiaradonna F
- Chiarelli R
- Chiariello M
- Chica N
- Chiocca S
- Chiong M
- Chiou S-H
- Chiramel AI
- ChiurchiĂč V
- Cho D-H
- Choe S-K
- Choi AMK
- Choi ME
- Choudhury KR
- Chow NS
- Chu CT
- Chua JJE
- Chua JP
- Chung H
- Chung KP
- Chung S
- Chung S-H
- Chung Y-L
- Cianfanelli V
- Ciechomska IA
- Cifuentes M
- Cinque L
- Cirak S
- Cirone M
- Clague MJ
- Clarke R
- Clementi E
- Coccia EM
- Codogno P
- Cohen E
- Cohen MM
- Colasanti T
- Colasuonno F
- Colbert RA
- Colell A
- Coll NS
- Collins MO
- Colombo MI
- ColĂłn-Ramos DA
- Combaret L
- Comincini S
- Cominetti MR
- Consiglio A
- Conte A
- Conti F
- Contu VR
- Cookson MR
- Coombs KM
- Coppens I
- Corasaniti MT
- Cordes N
- Corkery DP
- Cortese K
- Costa MDC
- Costantino S
- Costelli P
- Coto-Montes A
- Crack PJ
- Crespo JL
- Criollo A
- Crippa V
- Cristofani R
- Csizmadia T
- Cuadrado A
- Cui B
- Cui J
- Cui Y
- Cui Y
- Culetto E
- Cumino AC
- Cybulsky AV
- Czaja MJ
- Czuczwar SJ
- D'Adamo S
- D'Amelio M
- D'Arcangelo D
- D'Lugos AC
- D'Orazi G
- da Silva JA
- Dafsari HS
- Dagda RK
- Dagdas Y
- Daglia M
- Dai X
- Dai Y
- Dai Y
- Dal Col J
- Dalhaimer P
- Dalla Valle L
- Dallenga T
- Dalmasso G
- Damme M
- Dando I
- Dantuma NP
- Darling AL
- Das H
- Dasarathy S
- Dasari SK
- Dash S
- Daumke O
- Dauphinee AN
- Davies JS
- Davis RJ
- Davis T
- Dayalan Naidu S
- De Amicis F
- De Bosscher K
- De Felice F
- De Franceschi L
- De Leonibus C
- de Mattos Barbosa MG
- De Meyer GRY
- De Milito A
- De Nunzio C
- De Palma C
- De Santi M
- De Virgilio C
- De Zio D
- Debnath J
- DeBosch BJ
- Decuypere J-P
- Deehan MA
- Deflorian G
- DeGregori J
- Dehay B
- Del Rio G
- Delaney JR
- Delbridge LMD
- Delorme-Axford E
- Delpino MV
- Demarchi F
- Dembitz V
- Demers ND
- Deng H
- Deng Z
- Dengjel J
- Dent P
- Denton D
- DePamphilis ML
- Der CJ
- Deretic V
- Descoteaux A
- Devis L
- Devkota S
- Devuyst O
- Dewson G
- Dharmasivam M
- Dhiman R
- di Bernardo D
- Di Cristina M
- Di Domenico F
- Di Fazio P
- Di Fonzo A
- Di Guardo G
- Di Guglielmo GM
- Di Leo L
- Di Malta C
- Di Nardo A
- Di Rienzo M
- Di Sano F
- Diallinas G
- Diao J
- Diaz-Araya G
- Dickinson JM
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- Dikic I
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- Dinkova-Kostova AT
- Dionne MS
- Distler JHW
- Diwan A
- Dixon IMC
- Djavaheri-Mergny M
- Dobrinski I
- Dobrovinskaya O
- Dobrowolski R
- Dobson RCJ
- Dokmeci Emre S
- Donadelli M
- Dong B
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- Dorn Ii GW
- Dotsch V
- Dou H
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- Dridi S
- Drucker L
- du Toit A
- Du A
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- Dubrovska A
- Dunlop EA
- Dupont N
- DurĂĄn RV
- Dwarakanath BS
- Dyshlovoy SA
- DĂĄvila VA
- DĂaz-Laviada I
- Ebrahimi-Fakhari D
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- Eng CH
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- Engelsen AST
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- Ferrante AW
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- Ferreira JCB
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- Figueras A
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- Fisher EA
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- Flo TH
- Florance I
- Florey O
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- Fodor E
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- Frankel LB
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- GarcĂa-Moreno D
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- Xiao H-T
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- Xue Y
- Yakhine-Diop SMS
- Yamaguchi M
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- Yang WY
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- Yang Y
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- Yao H
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- Yao Y-M
- Yasui T
- Yazdankhah M
- Yen PM
- Yi C
- Yi-Ren Hong C-WH
- Yin X-M
- Yin Y
- Yin Z
- Yin Z
- Ying M
- Ying Z
- Yip CK
- Yiu SPT
- Yoo YH
- Yoshida K
- Yoshii SR
- Yoshimori T
- Yousefi B
- Yu B
- Yu H
- Yu J
- Yu J
- Yu L
- Yu M-L
- Yu S-W
- Yu VC
- Yu WH
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- Yu Z
- Yuan J
- Yuan L-Q
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- Yuan S-SF
- Yuan Y
- Yuan Z
- Yue J
- Yue Z
- Yun J
- Yung RL
- Zacks DN
- Zaffagnini G
- Zambelli VO
- Zanella I
- Zang QS
- Zanivan S
- Zappavigna S
- Zaragoza P
- Zarbalis KS
- Zarebkohan A
- Zarrouk A
- Zeitlin SO
- Zeng J
- Zeng J-D
- Zhan L
- Zhang B
- Zhang DD
- Zhang H
- Zhang H
- Zhang H
- Zhang H
- Zhang H
- Zhang H
- Zhang H
- Zhang H-L
- Zhang J
- Zhang J
- Zhang J-P
- Zhang KYB
- Zhang L
- Zhang L
- Zhang L
- Zhang L
- Zhang LW
- Zhang M
- Zhang P
- Zhang S
- Zhang W
- Zhang X
- Zhang X
- Zhang X
- Zhang X
- Zhang X
- Zhang X-W
- Zhang XD
- Zhang Y
- Zhang Y
- Zhang Y
- Zhang Y
- Zhang Y
- Zhang Y-D
- Zhang Y-Y
- Zhang Z
- Zhang Z
- Zhang Z
- Zhang Z
- Zhang Z
- Zhang Z
- Zhao H
- Zhao L
- Zhao S
- Zhao T
- Zhao X-F
- Zhao Y
- Zhao Y
- Zhao Y
- Zhao Y
- Zheng G
- Zheng K
- Zheng L
- Zheng S
- Zheng X-L
- Zheng Y
- Zheng Z-G
- Zhivotovsky B
- Zhong Q
- Zhou A
- Zhou B
- Zhou C
- Zhou G
- Zhou H
- Zhou H
- Zhou H
- Zhou J
- Zhou J
- Zhou J
- Zhou J
- Zhou K
- Zhou R
- Zhou X-J
- Zhou Y
- Zhou Y
- Zhou Y
- Zhou Z
- Zhou Z-Y
- Zhu B
- Zhu C
- Zhu G-Q
- Zhu H
- Zhu H
- Zhu H
- Zhu W-G
- Zhu Y
- Zhu Y
- Zhuang H
- Zhuang X
- Zientara-Rytter K
- Zimmermann CM
- Ziviani E
- Zoladek T
- Zong W-X
- Zorov DB
- Zorzano A
- Zou W
- Zou Z
- Zou Z
- Zuryn S
- Zwerschke W
- Ălvarez ĂMC
- Ăvalos Y
- Ănal G
- ĂstĂŒn S
- ÄoliÄ M
- ÄokiÄ J
- Ćœerovnik E
- Publication venue
- 'Informa UK Limited'
- Publication date
- 01/01/2021
- Field of study
In 2008, we published the first set of guidelines for standardizing research in autophagy. Since then, this topic has received increasing attention, and many scientists have entered the field. Our knowledge base and relevant new technologies have also been expanding. Thus, it is important to formulate on a regular basis updated guidelines for monitoring autophagy in different organisms. Despite numerous reviews, there continues to be confusion regarding acceptable methods to evaluate autophagy, especially in multicellular eukaryotes. Here, we present a set of guidelines for investigators to select and interpret methods to examine autophagy and related processes, and for reviewers to provide realistic and reasonable critiques of reports that are focused on these processes. These guidelines are not meant to be a dogmatic set of rules, because the appropriateness of any assay largely depends on the question being asked and the system being used. Moreover, no individual assay is perfect for every situation, calling for the use of multiple techniques to properly monitor autophagy in each experimental setting. Finally, several core components of the autophagy machinery have been implicated in distinct autophagic processes (canonical and noncanonical autophagy), implying that genetic approaches to block autophagy should rely on targeting two or more autophagy-related genes that ideally participate in distinct steps of the pathway. Along similar lines, because multiple proteins involved in autophagy also regulate other cellular pathways including apoptosis, not all of them can be used as a specific marker for bona fide autophagic responses. Here, we critically discuss current methods of assessing autophagy and the information they can, or cannot, provide. Our ultimate goal is to encourage intellectual and technical innovation in the field
Association of knowledge on ART line of treatment, scarcity of treatment options and adherence
- Author
- C Kanjala
- CA Koss
- Charles Muiruri
- D Boateng
- DL Paterson
- DR Bangsberg
- DR Bangsberg
- DR Bangsberg
- E Slaymaker
- Eileen S. Lirhunde
- Habib O. Ramadhani
- HO Ramadhani
- HO Ramadhani
- IB Wilson
- J Gare
- JJ Parienti
- John A. Bartlett
- Julian B. Mushi
- LM Terblanche
- M Mbonye
- MA Thompson
- Michael Omondi
- MS Cohen
- R Demessie
- R Zachariah
- SA Safren
- SP Wasti
- T BĂ€rnighausen
- V Senkomago
- Venance P. Maro
- Y Potchoo
- Y Sasaki
- Z El-Khatib
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
A bodhisattva-spirit-oriented counselling framework: inspired by Vimalakīrti wisdom
- Author
- A Cason
- A Comte
- A Glaser
- A Howard
- A Quinn
- A Rawlinson
- AB Baranowsky
- AF Bondarenko
- AH Maslow
- Ananda WP Guruge
- AT Morales
- AT Patsiopoulos
- B Cade
- B Magid
- BA Wallace
- BA Wallace
- BA Wallace
- BL Thompson
- BR Reichenbach
- BW Helm
- C Bankart Peter
- C Boeree
- C Brems
- C Humphreys
- C Laranjeira
- C Moran Carmen
- C Ray
- C Schwabenland
- C Trungpa
- Cheng Fung Kei
- CJ Arthur
- CK Germer
- CK Ng
- CP Bankart
- CR Marmar
- CR Rogers
- CR Rogers
- CR Rogers
- CR Rogers
- CR Rogers
- CR Rogers
- CV Thubten
- D Brandon
- D Brandon
- D Goleman
- D Goleman
- D Goleman
- D Hunt
- D Keown
- D Long
- D Lopez
- D Ponlop
- D Punter
- D Stone
- DC Brink
- DD Burns
- DE Ponce
- DM Larkin
- Dolliver
- DR Gehart
- DS Wright
- DT Ding
- DT Suzuki
- E Conze
- E Conze
- E Fromm
- E Fromm
- E Myers Charles
- E Podvoll
- E Witztum
- E Wray
- EP Lukens
- ER Canda
- F Han De Witt
- F Riessman
- F Silverberg
- FJ Kaklauskas
- FJ Kaklauskas
- FK Cheng
- G Callow
- G Ciuffardi
- G Claxton
- G Corey
- G Corey
- G Dudley-Grant
- G Storhoff
- G Sugamura
- G Watson
- GE Pruett
- GT Kwee Maurits
- GT Kwee Maurits
- H Abiko
- H Bergson
- H Dayal
- H Geybels
- H Kathleen Dockett
- H Kief
- H Markus
- H Solberg
- Hajimeäžæć Nakamura
- HC Hsu
- HJ You
- HR Glazer
- HV Lovelady
- I Wray
- ID Yalom
- IFWK Davidson
- J Banman
- J Bauml
- J Kabat-Zinn
- J Kabat-Zinn
- J Kornfield
- J Kornfield
- J Krieglstein Werner
- J Kristeller
- J Manne-Lewis
- J Phillips
- J Taels
- J Welwood
- J Welwood
- J Wilkins
- JA Smith
- JB Rubin
- JD Teasdale
- JD Whipps
- JD Zheng
- JG Williams
- JHD Cornelius-White
- JJ Prendergast
- JJ Prendergast
- JK Clarke
- JP He
- JP Klein
- JR Averill
- JS Roshi
- JW Schroeder
- K Boukydis
- K Cheng Fung
- K Jones
- K Mizuno
- K Sri Dhammanaha
- K Tada
- KD Neff
- KD Neff
- KD Neff
- KD Neff
- KJ Schneider
- Kuoching é»ćæž Huang
- L Basham Arthur
- L Dalai
- L Finlay
- L Hoffman
- L Suzuki Beatrice
- LE Beutler
- LE Crawford
- LJ Kirmayer
- LO Gomez
- LR Zopa
- LS Kawamura
- LV Sasaki
- LĂ Paul Marie
- M Abe
- M Batchelor
- M Buber
- M Deeg
- M Dow
- M Dynel
- M Emanatian
- M Epstein
- M Epstein
- M Epstein
- M Greene
- M Hsing-Yun
- M Johnson
- M McGoldrick
- M McMahon
- M Nagao Gadjin
- M Pye
- Master ć°é ć°ćž« Yin-Shun
- Master èćŽæłćž« Sheng-yen
- Mei èæą Lan
- MF Li
- ML Thigpen
- MQ Patton
- MR Walley
- MS Snow
- O Brown
- O Chang
- O Egbochuku Elizabeth
- P Bloom
- P De Silva
- P De Silva
- P Fenner
- P Harrison
- P Harvey
- P Heelas
- P Manternach Dean
- P Slater
- P Townsend
- P Williams
- P Young-Eisendrath
- PM Raskin
- PP Leung
- R Akizuki
- R Corless
- R Gethin
- R Lancaster Lewis
- R Loy David
- R McClary
- R McRae John
- R Rogers
- R Thurman
- R Walker
- R Wicks
- RA Miller
- RAF Thurman
- RB Mather
- RG Fielding
- RR Kopp
- RS Crane
- Ryuujou ç„æéæ·š Kanbayashi
- S Flowers
- S Inoue
- S Oi
- S Salzberg
- S Salzberg
- S Szkredka
- SA Safren
- SJ Parry
- SL Bertman
- SL Garfield
- SR Craig
- Susumuć±±ćŁç Yamaguchi
- SW Tam
- T Bernhard
- T Sugioka
- T Suzuki Daisetz
- T Walsh
- TD Leighton
- TE Bratter
- TH Lieu
- TP Kasulis
- U App
- V Eatough
- V Herck
- VJ Kain
- W Rahula
- W Rahula
- WE Soothill
- WP Lin
- WR McFarlane
- XT Shi
- Y Bronner
- Y Krishan
- Yuuiti æą¶ć±±éäž Kaziyama
- YZ Chen
- Z Kövecses
- ZY Lin
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
Examining Associations Between Cognitive-Affective Vulnerability and HIV Symptom Severity, Perceived Barriers to Treatment Adherence, and Viral Load Among HIV-Positive Adults
- Author
- A Aldao
- A Ammassari
- A Bernstein
- A Bernstein
- A Bernstein
- A Gonzalez
- A Gonzalez
- A Gonzalez
- AA Vujanovic
- Anka A. Vujanovic
- AR Webel
- AW Carrico
- BO Olatunji
- C Foster
- C OâCleirigh
- CP Brandt
- CP Brandt
- CS Carver
- D Rao
- DA Murphy
- DW Capron
- FJ Palella Jr
- GR Norton
- JB Saunders
- JF Boswell
- JM Simoni
- JS Simons
- JW Mellors
- KL Gratz
- KL Gratz
- KL Ocañez
- KW Brown
- LG Duncan
- LM Inserting
- M Johnson
- M Keough
- MA Chesney
- Marcel O. Bonn-Miller
- MB First
- ML Oser
- MM Azar
- MO Bonn-Miller
- MW Otto
- O GalĂĄrraga
- P Phillippot
- PF Cook
- RA DeHaas
- RK McHugh
- RK McHugh
- S Kripalani
- S Reiss
- S Reiss
- S Taylor
- SA Safren
- SL Keng
- T Leyro
- T Schulte
- T Simpson
- TC Quinn
- Teresa M. Leyro
- TF Babor
- TM Leyro
- V Kraaij
- V Kraaij
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 19/03/2014
- Field of study
Cabotegravir for HIV Prevention in Cisgender Men and Transgender Women
- Author
- Adeyeye A.
- Anderson P.
- Asmelash A.
- Blanchette C.
- Brown T.T.
- Bryan M.
- Cabello R.
- Chariyalertsak S.
- Clement M.E.
- Coelho L.
- Cohen M.S.
- Cottle L.
- Daar E.
- Del Rio C.
- Donnell D.
- Dunne E.F.
- Eron J.J.
- Eshleman S.H.
- Fields S.D.
- Frank I.
- Gallardo-Cartagena J.A.
- Gaur A.H.
- Gomez-Feliciano K.
- Gonzales P.
- Grinsztejn B.
- Gulick R.M.
- Hanscom B.
- Hendrix C.
- Hinojosa J.C.
- Holtz T.H.
- HPTN 083 Study Team
- Huamani J.V.
- Jennings A.
- Kallas E.G.
- Kelley C.F.
- Kofron R.M.
- Landovitz R.J.
- Li M.
- Losso M.H.
- Lucas J.
- Madruga J.V.
- Margolis D.
- Marrazzo J.
- Marzinke M.
- McCauley M.
- Middelkoop K.
- Overton E.T.
- Phanuphak N.
- Piwowar-Manning E.
- Psaros C.
- Richardson P.
- Rinehart A.
- Rooney J.F.
- Safren S.
- Santos B.
- Scott H.
- Shin K.
- Sista N.D.
- Smith K.Y.
- Spreen W.
- Sued O.
- Sugarman J.
- Sullivan P.
- Swaminathan S.
- Tran H.V.
- Wang Z.
- Publication venue
- Massachussetts Medical Society
- Publication date
- 01/01/2021
- Field of study
Background: Safe and effective long-acting injectable agents for preexposure prophylaxis (PrEP) for human immunodeficiency virus (HIV) infection are needed to increase the options for preventing HIV infection. Methods: We conducted a randomized, double-blind, double-dummy, noninferiority trial to compare long-acting injectable cabotegravir (CAB-LA, an integrase strand-transfer inhibitor [INSTI]) at a dose of 600 mg, given intramuscularly every 8 weeks, with daily oral tenofovir disoproxil fumarate-emtricitabine (TDF-FTC) for the prevention of HIV infection in at-risk cisgender men who have sex with men (MSM) and in at-risk transgender women who have sex with men. Participants were randomly assigned (1:1) to receive one of the two regimens and were followed for 153 weeks. HIV testing and safety evaluations were performed. The primary end point was incident HIV infection. Results: The intention-to-treat population included 4566 participants who underwent randomization; 570 (12.5%) identified as transgender women, and the median age was 26 years (interquartile range, 22 to 32). The trial was stopped early for efficacy on review of the results of the first preplanned interim end-point analysis. Among 1698 participants from the United States, 845 (49.8%) identified as Black. Incident HIV infection occurred in 52 participants: 13 in the cabotegravir group (incidence, 0.41 per 100 person-years) and 39 in the TDF-FTC group (incidence, 1.22 per 100 person-years) (hazard ratio, 0.34; 95% confidence interval, 0.18 to 0.62). The effect was consistent across prespecified subgroups. Injection-site reactions were reported in 81.4% of the participants in the cabotegravir group and in 31.3% of those in the TDF-FTC group. In the participants in whom HIV infection was diagnosed after exposure to CAB-LA, INSTI resistance and delays in the detection of HIV infection were noted. No safety concerns were identified. Conclusions: CAB-LA was superior to daily oral TDF-FTC in preventing HIV infection among MSM and transgender women. Strategies are needed to prevent INSTI resistance in cases of CAB-LA PrEP failure
Automated Crop Yield Estimation for Apple Orchards
- Publication venue
- Publication date
- 01/01/2013
- Field of study
Abstract Crop yield estimation is an important task in apple orchard management. The current manual sampling-based yield estimation is time-consuming, labor-intensive and inaccurate. To deal with this challenge, we developed a computer vision-based system for automated, rapid and accurate yield estimation. The system uses a two-camera stereo rig for image acquisition. It works at nighttime with controlled artificial lighting to reduce the variance of natural illumination. An autonomous orchard vehicle is used as the support platform for automated data collection. The system scans both sides of each tree row in orchards. A computer vision algorithm detects and registers apples from acquired sequential images, and then generates apple counts as crop yield estimation. We deployed the yield estimation system in Washington state in September, 2011. The results show that the system works well with both red and green apples in the tall-spindle planting system. The crop yield estimation errors are-3.2 % for a red apple block with about 480 trees, and 1.2 % for a green apple block with about 670 trees.
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Trajectories of treatment response in a cognitive-behavioral therapy intervention for depression and adherence in persons with HIV in South Africa
- Author
- Publication venue
- Elsevier B.V
- Publication date
- 15/12/2023
- Field of study
People with HIV (PHW) are at greater risk of depression than the general population. Insight into the time-to-treatment-response and predictors of response to psychotherapy may improve implementation in primary care.We assessed depression treatment response among 80 participants in a trial of cognitive-behavioral therapy for adherence and depression (CBT-AD) for PWH with MDD and suboptimal antiretroviral therapy (ART) adherence. Participants self-reported depressive symptoms (CESD) at each therapy session. Clinicians assessed participants' depression (HAMD), along with potential predictors of response, every four months for one year. Latent class analyses examined classes of responders for the active and the post-treatment phases. Regression analyses identified predictors of class membership for each phase.During the active treatment phase (CESD) we identified an early response (at session 2 and with continued trajectory of improvement) and a non-response group. There were also two classes during post-treatment (HAM-D): early responders (4-month) and late responders (12-month). Distress aversion was associated with lower likelihood of early response to CBT-AD (aOR = 0.74, 95%CI[0.56â0.90], p = .009), and social support was associated with increased likelihood of early response (aOR = 2.24, 95%CI[1.07â5.46], p = .045).Self-reported depression during the treatment phase may have resulted from social desirability bias.Most participants responded to CBT-AD early during treatment (89 %) and had sustained improvements in depression by 4 months (80 %). Distress aversion was a risk factor for late response, and social support was protective. Future research is needed to assess the optimal dose of CBT-AD in resource limited settings.âąCognitive Behavioural Therapy effectively treats depression and adherence in Persons with HIV. It therefore improves rates of viral suppression, more than treatment as usual.âąEarly self-reported improvements in depression most likely are the result of being in a trial. Improvement continued to occur throughout the acute treatment phase.âąClinician-rated depression over 4, 8 and 12 months also occurred, with steep improvement seen at 4 months.âąWhether or not shorter durations of therapy, delivered by nurses, is effective remains to be explored
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