Dielectric Conductivity of Cross-Linked Polyurethanes Modified with Heteropolynuclear Cu3Mn Complexes

The dielectric and relaxation properties of cross-linked polyurethane, modified with heteropolynuclear Cu3Mn(L4) complexes with various ligands in outer coordination sphere were analyzed by dielectric relaxation spectroscopy. It was shown, that the modifier introduction in polyurethane leads to conductivity level increasing due to: i) complex formation between functional groups of polyurethane and heteropolynuclear compounds and ii) increase in the macrochain mobility

Biofeedback treatment of proctogenic constipation in adults

Aim of investigation. To study efficacy of biological feedback treatment (BFT) at proctogenic constipation in adult patients.Material and methods. Overall 30 patients with proctogenic constipation and dyssynergia of pelvic floor muscles i.e. spasm of puborectalis muscle were included in original study and treated by BFT method. Mean age of patients was 31,2±9,8 year, men to women ratio was 1:5.Results. During treatment decrease in difficulty to defecate according to Rome-III criteria was observed in 22 (73,3%) patients. The other 8 (26,7%) patients demonstrated no improvement. According to subjective assessment of rectal evacuatory function by questioning before and after BFT statistically significant reduction of proctogenic constipation symptoms was revealed. By the data of objective investigation (profilometry and electromyography) signs of dyssynergia of pelvic floor muscles were revealed in no patient.Conclusions. The biological feedback is effective treatment method for proctogenic constipation, allowing to reduce symptoms in 73,3% of patients and to correct dyssynergia of pelvic floor muscles in all cases

Synthesis and Characterization of Electro-Explosive Magnetic Nanoparticles for Biomedical Applications

Nowadays there are new magnetic nanostructures based on bioactive metals with low toxicity and high efficiency for a wide range of biomedical applications including drugs delivery, antimicrobial drugs design, cells' separation and contrasting. For such applications it is necessary to develop highly magnetic particles with less than100 nm in size. In the present study magnetic nanoparticles Fe, Fe[3]O[4] and bimetallic Cu/Fe with the average size of 60- 90 nm have been synthesized by electrical explosion of wire in an oxygen or argon atmosphere. The produced nanoparticles have been characterized with transmission electron microscopy, X-ray phase analysis, and nitrogen thermal desorption. The synthesized particles have shown antibacterial activity to gram-positive (S. aureus, MRSA) and gramnegative (E. coli, P. aeruginosa) bacteria. According to the cytological data Fe, Fe[3]O[4]and Cu/Fe nanoparticles have effectively inhibited viability of cancer cell lines Neuro-2a and J774. The obtained nanoparticles are promising for new antimicrobial drugs and antitumor agents' developmen

Synthesis and Characterization of Electro-Explosive Magnetic Nanoparticles for Biomedical Applications

Nowadays there are new magnetic nanostructures based on bioactive metals with low toxicity and high efficiency for a wide range of biomedical applications including drugs delivery, antimicrobial drugs design, cells' separation and contrasting. For such applications it is necessary to develop highly magnetic particles with less than100 nm in size. In the present study magnetic nanoparticles Fe, Fe[3]O[4] and bimetallic Cu/Fe with the average size of 60- 90 nm have been synthesized by electrical explosion of wire in an oxygen or argon atmosphere. The produced nanoparticles have been characterized with transmission electron microscopy, X-ray phase analysis, and nitrogen thermal desorption. The synthesized particles have shown antibacterial activity to gram-positive (S. aureus, MRSA) and gramnegative (E. coli, P. aeruginosa) bacteria. According to the cytological data Fe, Fe[3]O[4]and Cu/Fe nanoparticles have effectively inhibited viability of cancer cell lines Neuro-2a and J774. The obtained nanoparticles are promising for new antimicrobial drugs and antitumor agents' developmen

Experience of rectosacropexy in treatment of patients with rectum prolapse

Aim of investigation. To analyze authors’ experience of rectosacropexy results at prolapse of the rectum. Material and methods. Original study included 137 patients who underwent surgery for prolapse of rectum in the State scientific center of coloproctology from January, 2007 to December, 2013. The main group have included 60 patients (43,8%) who had rectosacropexy, control group included 77 patients (56,2%) after back loop rectopexy.Results. Control examination was carried out in 24 patients (40%) of the main and in 26 patients (33,8%) of the control group. Average time of follow-up was respectively 9,8±2,0 months and 34,2±17,8 months. Relapse was diagnosed in 2 patients (7,6%) after back loop rectopexy. After surgical treatment of rectal prolapse statistically significant improvement of anal sphincter pressure was diagnosed in both groups at I and II degree of sphincter insufficiency. Application of rectosacropexy corrects pelvic floor descent syndrome and evacuatory function of the rectum. No deterioration of large intestinal transit after rectosacropexy was revealed (р>0,05). After back loop rectopexy deterioration of large intestinal emptying (р<0,05) was significant.Conclusions. Rectosacropexy is effective method of rectum prolapse treatment and improves function of anal sphincter in postoperative period, corrects pelvic floor descent syndrome and cause no constipation

Phase transitions and configuration space topology

Equilibrium phase transitions may be defined as nonanalytic points of thermodynamic functions, e.g., of the canonical free energy. Given a certain physical system, it is of interest to understand which properties of the system account for the presence of a phase transition, and an understanding of these properties may lead to a deeper understanding of the physical phenomenon. One possible approach of this issue, reviewed and discussed in the present paper, is the study of topology changes in configuration space which, remarkably, are found to be related to equilibrium phase transitions in classical statistical mechanical systems. For the study of configuration space topology, one considers the subsets M_v, consisting of all points from configuration space with a potential energy per particle equal to or less than a given v. For finite systems, topology changes of M_v are intimately related to nonanalytic points of the microcanonical entropy (which, as a surprise to many, do exist). In the thermodynamic limit, a more complex relation between nonanalytic points of thermodynamic functions (i.e., phase transitions) and topology changes is observed. For some class of short-range systems, a topology change of the M_v at v=v_t was proved to be necessary for a phase transition to take place at a potential energy v_t. In contrast, phase transitions in systems with long-range interactions or in systems with non-confining potentials need not be accompanied by such a topology change. Instead, for such systems the nonanalytic point in a thermodynamic function is found to have some maximization procedure at its origin. These results may foster insight into the mechanisms which lead to the occurrence of a phase transition, and thus may help to explore the origin of this physical phenomenon.Comment: 22 pages, 6 figure

Singularities, Lax degeneracies and Maslov indices of the periodic Toda chain

The n-particle periodic Toda chain is a well known example of an integrable but nonseparable Hamiltonian system in R^{2n}. We show that Sigma_k, the k-fold singularities of the Toda chain, ie points where there exist k independent linear relations amongst the gradients of the integrals of motion, coincide with points where there are k (doubly) degenerate eigenvalues of representatives L and Lbar of the two inequivalent classes of Lax matrices (corresponding to degenerate periodic or antiperiodic solutions of the associated second-order difference equation). The singularities are shown to be nondegenerate, so that Sigma_k is a codimension-2k symplectic submanifold. Sigma_k is shown to be of elliptic type, and the frequencies of transverse oscillations under Hamiltonians which fix Sigma_k are computed in terms of spectral data of the Lax matrices. If mu(C) is the (even) Maslov index of a closed curve C in the regular component of R^{2n}, then (-1)^{\mu(C)/2} is given by the product of the holonomies (equal to +/- 1) of the even- (or odd-) indexed eigenvector bundles of L and Lmat.Comment: 25 pages; published versio

Комплексное лечение больных с циррозом печени, осложненным кровотечением

This article deals with analysis of own experience of treatment of portal hypertension patients complicated with variceal bleeding. There were 390 patients with cirrhosis complicated with variceal bleeding under our supervision from 2006 to 2012. Endoscopic hemostasis was carried out in 296 patients, 158 patients of them were conducted endoscopic sclerotherapy, 98 — endoscopic clipping and ligation and 40 patients — endoscopic sealing. After a stop of bleeding and stabilization of patient condition in 82 cases for prevention of recurrence of bleedings we carried out endovascular embolization of a splenic artery by the technique which we elaborated ourselves. In 52 cases for the purpose of bleedings recurrence prevention we performed laparoscopic operations which consisted in coagulation and ligation of short veins and stomach arteries on big curvature. The remote results after only an endoscopic hemostasis, and an endoscopic hemostasis with the subsequent performance of laparoscopic and endovascular operations have been observed in 190 patients during 3 years. The most effective method of a local hemostasis is the endoscopic ligation and clipping of varices. Endovascular embolization of the splenic artery and also a laparoscopic devascularization of cardiac part of the stomach and abdominal part of the esophagus allows to reduce considerably frequency of bleedings recurrence and lethality in the remote period.В этой статье мы проанализировали наш опыт лечения пациентов с портальной гипертензией, осложненной кровотечениями из варикозно расширенных вен. С 2006 по 2012 гг. под нашим наблюдением было 390 пациентов с циррозом, осложненным кровотечением из варикозно расширенных вен. Из 296 пациентов, которым мы выполняли эндоскопический гемостаз, 158 больным выполняли эндоскопическую склеротерапию, 98 — эндоскопическое лигирование и 40 — прошивание через стенку желудка. После остановки кровотечения и стабилизации состояния пациентов в 82 случаях для профилактики рецидивов кровотечений мы выполняли эндоваскулярную эмболизацию селезеночной артерии по методике, модифицированной нами. В 52 случаях для профилактики рецидивов кровотечений мы выполняли лапароскопические операции портоазигального разобщения с коагуляцией и клипированием сосудов желудка. Эндоваскулярная эмболизация и лапароскопическая деваскуляризация сосудов желудка и нижней трети пищевода позволили значительно сократить частоту рецидивов кровотечений и летальность у этой тяжелой категории больных в ближайшем и отдаленном периодах

Geometry of integrable dynamical systems on 2-dimensional surfaces

This paper is devoted to the problem of classification, up to smooth isomorphisms or up to orbital equivalence, of smooth integrable vector fields on 2-dimensional surfaces, under some nondegeneracy conditions. The main continuous invariants involved in this classification are the left equivalence classes of period or monodromy functions, and the cohomology classes of period cocycles, which can be expressed in terms of Puiseux series. We also study the problem of Hamiltonianization of these integrable vector fields by a compatible symplectic or Poisson structure.Comment: 31 pages, 12 figures, submitted to a special issue of Acta Mathematica Vietnamic

TEMPORARY PEDICLE FLAP GRAFTING IN TREATMENT OF PATIENTS WITH INJURIES AND SCARS

Aim. The aim of our work was to study the results of surgical treatment of patients with the temporary pedicle flaps grafting in the recovery of shed skin cover.Materials and methods. 97 cases of the flaps use for the treatment of 92 patients aged from 9 months to 63 years were analyzed. All patients were treated in the Burn Unit of the Scientific Research Institute – S.V. Ochapovsky Regional Clinical Hospital №1 with thermal, electrical, and mechanical injuries and their consequences within 2006-2017.Results. “Acute” flaps grafting was performed in 58 (63%) patients (61 flaps), prefabrication of flaps was performed in 34 (37%) patients (36 flaps). From the migration of the flap to its modeling, the patients underwent the immobilization of interconnected areas of the body. This period was from 24,1±1,8 to 40.9±13.7 days and depended on the characteristics of the flap and its preliminary preparation. Artificial syndactylies were made in 24.4% cases of hands surgeries. It required additional surgical correction later. Conclusion. Despite the duration and multiple stages, temporary pedicle flaps grafting sometimes remains the only feasible method of surgical treatment aimed at correction of defects of the skin and preservation of deep anatomical structures