The Brightest Cluster Galaxy in Abell 85: The Largest Core Known so far

We have found that the brightest cluster galaxy (BCG) in Abell~85, Holm 15A, displays the largest core so far known. Its cusp radius, $r_{\gamma} = 4.57 \pm 0.06$ kpc ($4.26^{\prime\prime}\pm 0.06^{\prime\prime}$), is more than 18 times larger than the mean for BCGs, and $\geq1$ kpc larger than A2261-BCG, hitherto the largest-cored BCG (Postman, Lauer, Donahue, et al. 2012) Holm 15A hosts the luminous amorphous radio source 0039-095B and has the optical signature of a LINER. Scaling laws indicate that this core could host a supermassive black hole (SMBH) of mass $M_{\bullet}\thicksim (10^{9}-10^{11})\,M_{\odot}$. We suggest that cores this large represent a relatively short phase in the evolution of BCGs, whereas the masses of their associated SBMH might be set by initial conditions.Comment: 14 pages, 3 figure, 2 tables, accepted for publication in ApJ Letters on October 6th, 2014, replacement of previous manuscript submitted on May 30th, 2014 to astro-p

Synthesis and characterization of a click-assembled 18-atom macrocycle that displays selective AXL kinase inhibitory activity

A novel macrocyclic construct consisting of a pyrazolopyrimidine scaffold concatenated to a benzene ring through two triazoles has been developed to investigate uncharted chemical space with bioactive potential. The 18-atom macrocycle was assembled via a double copper-catalyzed alkyne−azide cycloaddition (CuAAC) reaction between 1,3- bis(azidomethyl)benzene and a bis-propargylated pyrazolo[3,4-d]pyrimidine core. The resulting macrocycle was functionalized further into a multicyclic analog that displays selective inhibitory activity against the receptor tyrosine kinase AXL.O.C.-L. and B.L. thank Spain Ministry of Education, Culture and Sport and the Erasmus + Traineeship programme for funding, respectively. C.T. thanks the CMVM for a Principal’s Scholarship. F.F. acknowledges support from Universidad de Granada. SHM and AU-B are grateful to Scottish Power and CRUK for funding

Galaxy and Mass Assembly (GAMA): The interplay between galaxy mass, SFR, and heavy element abundance in paired galaxy sets

© 2021 2020 The Author(s) Published by Oxford University Press on behalf of Royal Astronomical Society. We study the star formation rate (SFR), stellar mass (M∗), and the gas metallicity (Z) for 4636 galaxy pairs using the Galaxy And Mass Assembly (GAMA) survey. Our galaxy pairs lie in a redshift range of 0 250 km s-1 and high multiplicity

Possible seismogenic origin of changes in the ULF EM resonant structure observed at Teoloyucan geomagnetic station, Mexico, 1999-2001

International audienceThe evolution of the ULF resonant structure observed at Teoloyucan geomagnetic station has been provisionally studied in a possible relation with seismic activity in Mexico in the period 1999-2001. Two resonant lines were observed in the H-component (linear polarization) in the frequency bands fR2=10.2?11.1 mHz and fR2=13.6?14.5 mHz, sometimes accompanied by other harmonics. The source of the observed resonances is possibly related with the geomagnetic location of the station (geomagnetic latitude ?=29.1°) and its proximity to the equatorial electrojet (?~30°). An enhancement of the carrier frequency of both resonances in the period 1 month?2 weeks was found before the strongest EQs. Also, a depression of the resonant structure just a few days before and a few days after some EQs seems to be correlated with seismic activity