76 research outputs found
Design and performance of an aerodynamic molecular beam and beam detection system
Design and performance of aerodynamic molecular beam syste
Intracavity Raman Scattering from Molecular Beams: Direct Determination of Local Properties in an Expanding Jet Beam
Interface Excitons in Krmnen Clusters : The Role of Electron Affinity in the Formation of Electronic Structure
The formation of the electronic structure of small Kr_m clusters (m<150)
embedded inside Ne_N clusters (1200<N<7500) has been investigated with the help
of fluorescence excitation spectroscopy using synchrotron radiation.
Electronically excited states, assigned to excitons at the Ne/Kr interface, 1i
and 1'i were observed. The absorption bands, which are related to the lowest
spin-orbit split atomic Kr 3P1 and 1P1 states, initially appear and shift
towards lower energy when the krypton cluster size m increases. The
characteristic bulk 1t and 1't excitons appear in the spectra, when the cluster
radius exceeds some critical value, R_cl>Delta_1i . Kr clusters comprising up
to 70 atoms do not exhibit bulk absorption bands. We suggest that this is due
to the penetration of the interface excitons into the Kr_m cluster volume,
because of the negative electron affinity of surrounding Ne atoms. From the
energy shift of the interface absorption bands with cluster size an
unexpectedly large penetration depth of delta_1i =7.0+/-0.1 A is estimated,
which can be explained by the interplay between the electron affinities of the
guest and the host cluster
Strong X-Ray Emission from High-Temperature Plasmas Produced by Intense Irradiation of Clusters
Molecular-dynamics simulations in systems of rare gases using Axilrod-Teller and exchange three-atom interactions
The comorbidity and co-medication profile of patients with progressive supranuclear palsy
Background: Progressive supranuclear palsy (PSP) is usually diagnosed in elderly. Currently, little is known about comorbidities and the co-medication in these patients. Objectives: To explore the pattern of comorbidities and co-medication in PSP patients according to the known different phenotypes and in comparison with patients without neurodegenerative disease. Methods: Cross-sectional data of PSP and patients without neurodegenerative diseases (non-ND) were collected from three German multicenter observational studies (DescribePSP, ProPSP and DANCER). The prevalence of comorbidities according to WHO ICD-10 classification and the prevalence of drugs administered according to WHO ATC system were analyzed. Potential drug–drug interactions were evaluated using AiDKlinik®. Results: In total, 335 PSP and 275 non-ND patients were included in this analysis. The prevalence of diseases of the circulatory and the nervous system was higher in PSP at first level of ICD-10. Dorsopathies, diabetes mellitus, other nutritional deficiencies and polyneuropathies were more frequent in PSP at second level of ICD-10. In particular, the summed prevalence of cardiovascular and cerebrovascular diseases was higher in PSP patients. More drugs were administered in the PSP group leading to a greater percentage of patients with polypharmacy. Accordingly, the prevalence of potential drug–drug interactions was higher in PSP patients, especially severe and moderate interactions. Conclusions: PSP patients possess a characteristic profile of comorbidities, particularly diabetes and cardiovascular diseases. The eminent burden of comorbidities and resulting polypharmacy should be carefully considered when treating PSP patients
Growth of nanostructures by cluster deposition : a review
This paper presents a comprehensive analysis of simple models useful to
analyze the growth of nanostructures obtained by cluster deposition. After
detailing the potential interest of nanostructures, I extensively study the
first stages of growth (the submonolayer regime) by kinetic Monte-Carlo
simulations. These simulations are performed in a wide variety of experimental
situations : complete condensation, growth with reevaporation, nucleation on
defects, total or null cluster-cluster coalescence... The main scope of the
paper is to help experimentalists analyzing their data to deduce which of those
processes are important and to quantify them. A software including all these
simulation programs is available at no cost on request to the author. I
carefully discuss experiments of growth from cluster beams and show how the
mobility of the clusters on the surface can be measured : surprisingly high
values are found. An important issue for future technological applications of
cluster deposition is the relation between the size of the incident clusters
and the size of the islands obtained on the substrate. An approximate formula
which gives the ratio of the two sizes as a function of the melting temperature
of the material deposited is given. Finally, I study the atomic mechanisms
which can explain the diffusion of the clusters on a substrate and the result
of their mutual interaction (simple juxtaposition, partial or total
coalescence...)Comment: To be published Rev Mod Phys, Oct 99, RevTeX, 37 figure
The comorbidity and co-medication profile of patients with progressive supranuclear palsy
Background
Progressive supranuclear palsy (PSP) is usually diagnosed in elderly. Currently, little is known about comorbidities and the co-medication in these patients.
Objectives
To explore the pattern of comorbidities and co-medication in PSP patients according to the known different phenotypes and in comparison with patients without neurodegenerative disease.
Methods
Cross-sectional data of PSP and patients without neurodegenerative diseases (non-ND) were collected from three German multicenter observational studies (DescribePSP, ProPSP and DANCER). The prevalence of comorbidities according to WHO ICD-10 classification and the prevalence of drugs administered according to WHO ATC system were analyzed. Potential drug–drug interactions were evaluated using AiDKlinik®.
Results
In total, 335 PSP and 275 non-ND patients were included in this analysis. The prevalence of diseases of the circulatory and the nervous system was higher in PSP at first level of ICD-10. Dorsopathies, diabetes mellitus, other nutritional deficiencies and polyneuropathies were more frequent in PSP at second level of ICD-10. In particular, the summed prevalence of cardiovascular and cerebrovascular diseases was higher in PSP patients. More drugs were administered in the PSP group leading to a greater percentage of patients with polypharmacy. Accordingly, the prevalence of potential drug–drug interactions was higher in PSP patients, especially severe and moderate interactions.
Conclusions
PSP patients possess a characteristic profile of comorbidities, particularly diabetes and cardiovascular diseases. The eminent burden of comorbidities and resulting polypharmacy should be carefully considered when treating PSP patients
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