Comparison of the predictive performance of the BIG, TRISS, and PS09 score in an adult trauma population derived from multiple international trauma registries

The BIG score (Admission base deficit (B), International normalized ratio (I), and Glasgow Coma Scale (G)) has been shown to predict mortality on admission in pediatric trauma patients. The objective of this study was to assess its performance in predicting mortality in an adult trauma population, and to compare it with the existing Trauma and Injury Severity Score (TRISS) and probability of survival (PS09) score. A retrospective analysis using data collected between 2005 and 2010 from seven trauma centers and registries in Europe and the United States of America was performed. We compared the BIG score with TRISS and PS09 scores in a population of blunt and penetrating trauma patients. We then assessed the discrimination ability of all scores via receiver operating characteristic (ROC) curves and compared the expected mortality rate (precision) of all scores with the observed mortality rate. In total, 12,206 datasets were retrieved to validate the BIG score. The mean ISS was 15 ± 11, and the mean 30-day mortality rate was 4.8%. With an AUROC of 0.892 (95% confidence interval (CI): 0.879 to 0.906), the BIG score performed well in an adult population. TRISS had an area under ROC (AUROC) of 0.922 (0.913 to 0.932) and the PS09 score of 0.825 (0.915 to 0.934). On a penetrating-trauma population, the BIG score had an AUROC result of 0.920 (0.898 to 0.942) compared with the PS09 score (AUROC of 0.921; 0.902 to 0.939) and TRISS (0.929; 0.912 to 0.947). The BIG score is a good predictor of mortality in the adult trauma population. It performed well compared with TRISS and the PS09 score, although it has significantly less discriminative ability. In a penetrating-trauma population, the BIG score performed better than in a population with blunt trauma. The BIG score has the advantage of being available shortly after admission and may be used to predict clinical prognosis or as a research tool to risk stratify trauma patients into clinical trial

Varied pathways of river-borne clay minerals in a near-shore marine region: A case study of sediments from the Elbe- and Weser rivers, and the SE North Sea.

International audienc

Mesozoic hydrothermal impact on Rotliegende and Bunter immature sandstones of the High Rhine trough and its adjacent eastern area (southern Black Forest, Germany)

International audienc

Zeitschrift für Geophysik 23

Dieser Band enthält 25 Artikel zu Themengebieten der Physik der festen Erde, zu magnetischen und elektrischen Feldern der Erde, zu der Physik der Atmophäre, zu der Physik des Meeres und der Gewässer und der angewandten Geophysik veröffentlicht durch die Deutsche Geophysikalische Gesellschaft in dem Jahr 1957. Titelseite Autorenverzeichnis Sachverzeichnis Heft 1 (Brockamp, B.) Titelseite Inhaltsverzeichnis Zur Neubestimmung der absoluten Schwere in Potsdam (Reicheneder, K.) Über die bisherigen Erfahrungen und Meßergebnisse mit dem Seegravimeter (Graf, A.) Anwendungen der Methode der induzierten Polarisation an schwedischen Erzlagerstätten (Buchheim, W.) Untersuchungen über Perioden von Erdbebenwellen in Abhängigkeit von Herdgebiet und Herdentfernung (Deist, H. J., Dohr, G.) Zur Messung der Inklination mit Kippspule und langperiodischem Galvanometer (Burkhart, K.) Elektrokinetische Grenzflächenerscheinungen im Bereich oberflächennaher Erdschichten (Wilckens, F.) Heft 2 (Brockamp, B.) Titelseite Inhaltsverzeichnis Dynamik und Sediment-Transport an der Wattoberfläche des Weserästuars (Lüneburg, H.) Über erdmagnetische Absolut- und Vergleichsmessungen (Wiese, H.) Zur Frage der "scheinbaren" und "wirklichen Neigung"(Ullmann, W., Maaz, R.) Über die Entstehung der Mikroseismik (Hardtwig, E.) Heft 3 (Brockamp, B.) Titelseite Inhaltsverzeichnis Solare Ultrastrahlung und ionosphärische D-Schicht am 23. Februar 1956 (Ehmert, A., Revellio, K.) Asymptotische Formeln zur Bestimmung des von einer oder von mehreren Elektroden im geschichteten Boden hervorgerufenen Potentials (Belluigi, A.) Heft 4 (Brockamp, B.) Titelseite Inhaltsverzeichnis Über die Nachprüfung von magnetischen Messungen mit dem Lokal-Variometer von J. Wüst und die Feststellung der Ursachen der gefundenen magnetischen Störungen (Reich, H.) Asymptotische Formeln zur Bestimmung des von einer oder von mehreren Elektroden im geschichteten Boden hervorgerufenen Potentials (Fortsetzung) (Belluigi, A.) Über die Veränderlichkeit des erdmagnetischen Hauptfeldes und seine Theorien (Lucke, O.) Heft 5 (Brockamp, B.) Titelseite Inhaltsverzeichnis Reflexionen aus dem kristallinen Untergrund im Gebiet des Pfälzer Berglandes (Schulz, G.) Die seismische Bestimmung der Grundwassertiefe (Broße, P.) Eisseismische Untersuchungen (Brockamp, B.) Schallgeschwindigkeitsmessungen von Eis in Abhängigkeit von Druck und Temperatur (Lotze, W.) Die hypsometrische Kurve des Mondes (Joksch, H. C.) Statistischer Nachweis von Gezeiten in Binnenseen, dargestellt am Beispiel des Bodensees (Dohr, G.) Heft 6 (Brockamp, B.) Titelseite Inhaltsverzeichnis Methoden zur Bestimmung der räumlichen Gradienten des geomagnetischen Feldes (Schmidt, H.) Fehler und Korrekturen bei seismischen Messungen in Gebieten mit bewegtem Oberflächenrelief (Meißner, R.) Stereoskopische Vektorregistrierung (Strobach, K.) Spectrum of P and S in records of distant earthquakes (Gutenburg, B.) [Werbung] researchDGG, DFG, SUB Göttinge

Comparison of the predictive performance of the BIG, TRISS and PS09 score in an adult trauma population derived from multiple international trauma registries

Abstract Background The BIG score (Admission base deficit (B), International normalized ratio (I), and Glasgow Coma Scale (G)) has been shown to predict mortality on admission in pediatric trauma patients. The objective of this study was to assess its performance in predicting mortality in an adult trauma population, and to compare it with the existing Trauma and Injury Severity Score (TRISS) and probability of survival (PS09) score. Materials and methods A retrospective analysis using data collected between 2005 and 2010 from seven trauma centers and registries in Europe and the United States of America was performed. We compared the BIG score with TRISS and PS09 scores in a population of blunt and penetrating trauma patients. We then assessed the discrimination ability of all scores via receiver operating characteristic (ROC) curves and compared the expected mortality rate (precision) of all scores with the observed mortality rate. Results In total, 12,206 datasets were retrieved to validate the BIG score. The mean ISS was 15 ± 11, and the mean 30-day mortality rate was 4.8%. With an AUROC of 0.892 (95% confidence interval (CI): 0.879 to 0.906), the BIG score performed well in an adult population. TRISS had an area under ROC (AUROC) of 0.922 (0.913 to 0.932) and the PS09 score of 0.825 (0.915 to 0.934). On a penetrating-trauma population, the BIG score had an AUROC result of 0.920 (0.898 to 0.942) compared with the PS09 score (AUROC of 0.921; 0.902 to 0.939) and TRISS (0.929; 0.912 to 0.947). Conclusions The BIG score is a good predictor of mortality in the adult trauma population. It performed well compared with TRISS and the PS09 score, although it has significantly less discriminative ability. In a penetrating-trauma population, the BIG score performed better than in a population with blunt trauma. The BIG score has the advantage of being available shortly after admission and may be used to predict clinical prognosis or as a research tool to risk stratify trauma patients into clinical trials