A Mathematical Theory of Stochastic Microlensing II. Random Images, Shear, and the Kac-Rice Formula

Continuing our development of a mathematical theory of stochastic microlensing, we study the random shear and expected number of random lensed images of different types. In particular, we characterize the first three leading terms in the asymptotic expression of the joint probability density function (p.d.f.) of the random shear tensor at a general point in the lens plane due to point masses in the limit of an infinite number of stars. Up to this order, the p.d.f. depends on the magnitude of the shear tensor, the optical depth, and the mean number of stars through a combination of radial position and the stars' masses. As a consequence, the p.d.f.s of the shear components are seen to converge, in the limit of an infinite number of stars, to shifted Cauchy distributions, which shows that the shear components have heavy tails in that limit. The asymptotic p.d.f. of the shear magnitude in the limit of an infinite number of stars is also presented. Extending to general random distributions of the lenses, we employ the Kac-Rice formula and Morse theory to deduce general formulas for the expected total number of images and the expected number of saddle images. We further generalize these results by considering random sources defined on a countable compact covering of the light source plane. This is done to introduce the notion of {\it global} expected number of positive parity images due to a general lensing map. Applying the result to microlensing, we calculate the asymptotic global expected number of minimum images in the limit of an infinite number of stars, where the stars are uniformly distributed. This global expectation is bounded, while the global expected number of images and the global expected number of saddle images diverge as the order of the number of stars.Comment: To appear in JM

A Theorem on the origin of Phase Transitions

For physical systems described by smooth, finite-range and confining microscopic interaction potentials V with continuously varying coordinates, we announce and outline the proof of a theorem that establishes that unless the equipotential hypersurfaces of configuration space \Sigma_v ={(q_1,...,q_N)\in R^N | V(q_1,...,q_N) = v}, v \in R, change topology at some v_c in a given interval [v_0, v_1] of values v of V, the Helmoltz free energy must be at least twice differentiable in the corresponding interval of inverse temperature (\beta(v_0), \beta(v_1)) also in the N -> \infty$limit. Thus the occurrence of a phase transition at some \beta_c =\beta(v_c) is necessarily the consequence of the loss of diffeomorphicity among the {\Sigma_v}_{v < v_c}$ and the {\Sigma_v}_{v > v_c}, which is the consequence of the existence of critical points of V on \Sigma_{v=v_c}, that is points where \nabla V=0.Comment: 10 pages, Statistical Mechanics, Phase Transitions, General Theory. Phys. Rev. Lett., in pres

Billiards in a general domain with random reflections

We study stochastic billiards on general tables: a particle moves according to its constant velocity inside some domain ${\mathcal D} \subset {\mathbb R}^d$ until it hits the boundary and bounces randomly inside according to some reflection law. We assume that the boundary of the domain is locally Lipschitz and almost everywhere continuously differentiable. The angle of the outgoing velocity with the inner normal vector has a specified, absolutely continuous density. We construct the discrete time and the continuous time processes recording the sequence of hitting points on the boundary and the pair location/velocity. We mainly focus on the case of bounded domains. Then, we prove exponential ergodicity of these two Markov processes, we study their invariant distribution and their normal (Gaussian) fluctuations. Of particular interest is the case of the cosine reflection law: the stationary distributions for the two processes are uniform in this case, the discrete time chain is reversible though the continuous time process is quasi-reversible. Also in this case, we give a natural construction of a chord "picked at random" in ${\mathcal D}$, and we study the angle of intersection of the process with a $(d-1)$-dimensional manifold contained in ${\mathcal D}$.Comment: 50 pages, 10 figures; To appear in: Archive for Rational Mechanics and Analysis; corrected Theorem 2.8 (induced chords in nonconvex subdomains

The Point Processes of the GRW Theory of Wave Function Collapse

The Ghirardi-Rimini-Weber (GRW) theory is a physical theory that, when combined with a suitable ontology, provides an explanation of quantum mechanics. The so-called collapse of the wave function is problematic in conventional quantum theory but not in the GRW theory, in which it is governed by a stochastic law. A possible ontology is the flash ontology, according to which matter consists of random points in space-time, called flashes. The joint distribution of these points, a point process in space-time, is the topic of this work. The mathematical results concern mainly the existence and uniqueness of this distribution for several variants of the theory. Particular attention is paid to the relativistic version of the GRW theory that I developed in 2004.Comment: 72 pages LaTeX, 3 figure

Ruelle-Perron-Frobenius spectrum for Anosov maps

We extend a number of results from one dimensional dynamics based on spectral properties of the Ruelle-Perron-Frobenius transfer operator to Anosov diffeomorphisms on compact manifolds. This allows to develop a direct operator approach to study ergodic properties of these maps. In particular, we show that it is possible to define Banach spaces on which the transfer operator is quasicompact. (Information on the existence of an SRB measure, its smoothness properties and statistical properties readily follow from such a result.) In dimension $d=2$ we show that the transfer operator associated to smooth random perturbations of the map is close, in a proper sense, to the unperturbed transfer operator. This allows to obtain easily very strong spectral stability results, which in turn imply spectral stability results for smooth deterministic perturbations as well. Finally, we are able to implement an Ulam type finite rank approximation scheme thus reducing the study of the spectral properties of the transfer operator to a finite dimensional problem.Comment: 58 pages, LaTe

Combinatorial effects on gene expression at the Lbx1/Fgf8 locus resolve Split-Hand/Foot Malformation type 3

Split-Hand/Foot Malformation type 3 (SHFM3) is a congenital limb malformation associated with tandem duplications at the LBX1/FGF8 locus. Yet, the disease patho-mechanism remains unsolved. Here we investigated the functional consequences of SHFM3-associated rearrangements on chromatin conformation and gene expression in vivo in transgenic mice. We show that the Lbx1/Fgf8 locus consists of two separate, but interacting, regulatory domains. Re-engineering of a SHFM3-associated duplication and a newly reported inversion in mice resulted in restructuring of the chromatin architecture. This led to an ectopic activation of the Lbx1 and Btrc genes in the apical ectodermal ridge (AER) in an Fgf8-like pattern. Artificial repositioning of the AER-specific enhancers of Fgf8 was sufficient to induce misexpression of Lbx1 and Btrc. We provide evidence that the SHFM3 phenotype is the result of a combinatorial effect on gene misexpression and dosage in the developing limb. Our results reveal new insights into the molecular mechanism underlying SHFM3 and provide novel conceptual framework for how genomic rearrangements can cause gene misexpression and disease

Finite-dimensional global and exponential attractors for the reaction-diffusion problem with an obstacle potential

A reaction-diffusion problem with an obstacle potential is considered in a bounded domain of $\R^N$. Under the assumption that the obstacle \K is a closed convex and bounded subset of $\mathbb{R}^n$ with smooth boundary or it is a closed $n$-dimensional simplex, we prove that the long-time behavior of the solution semigroup associated with this problem can be described in terms of an exponential attractor. In particular, the latter means that the fractal dimension of the associated global attractor is also finite