The Effect of Interactive Computer Animations Accompanied with Experiments on Grade 6th Students’ Achievements and Attitudes toward Science

The aim of the present study was to investigate the effect of instruction including interactive computer animations accompanied with experiments over traditionally designed Instruction in 6th grade students’ physics achievement and attitudes toward science. In this study, a quasi-experimental pretest-posttest design was used. As a data collection instruments, physics achievement test and attitude scale toward science were administered to experimental and control group. In the experimental group, the materials were used while doing the experiments and then they did the same experiments interactively on the computer. In the control group, the experiments were done only by materials and the students did not use the computer during the experiments. The findings indicated that there was no significant difference between groups with respect to achievement before the treatment and there was a significant difference between the groups in favor of experimental groups after the treatment. The means of attitude towards science showed no significant difference between the groups before and after treatment

After 2015 national arrhythmia congress

PubMedID: 25880299[No abstract available

The effect of using different yeast species on the composition of carbohydrates and volatile aroma compounds in kefir drinks

Kefir is a fermented dairy product known for its high content of lactic acid bacteria and various types of yeast. The yeast microorganisms present in kefir cultures play a crucial role in shaping the distinctive characteristics of kefir. This study aimed to investigate the impact of different yeast species commonly used in industrial kefir production on the carbohydrate and volatile aroma components of kefir during the storage period. To this end, kefir cultures with various yeast species, including Debaryomyces hansenii (DH), Kluyveromyces marxianus (KM), Candida colliculosa (CC), Yarrowia lipolytica (YL), Saccharomyces bouardii (SB), Saccharomyces cerevisiae (SC), Kluyveromyces lactis (KL), and Geotricum candidum (GC), were prepared and utilized in kefir production. The study findings revealed significant effects of different yeast species on the composition of carbohydrate and volatile aroma components in kefir (p 0.05), with Klyveromyces spp. having particularly notable effects. It was observed that kefir drinks containing ethanol exhibited negligible lactose content, while their ethanol content was high. Kefir drinks containing minimal Klyveromyces marxianus contained glucose and galactose, whereas those containing Yarrowia lipolitica exhibited the lowest ethanol content. © 2023 Elsevier LtdThis research was supported by Ege University Scientific Research Projects Coordinatorship (Project No: FGA-2020-21581). The authors would like to thank EGE-MATAL (Ege University, Central Research Test and Analysis Laboratory Application and Research Center) for providing support in the analysis.FGA-2020-21581; Ege ÜniversitesiThis research was supported by Ege University Scientific Research Projects Coordinatorship (Project No: FGA-2020-21581 ). The authors would like to thank EGE-MATAL (Ege University, Central Research Test and Analysis Laboratory Application and Research Center) for providing support in the analysis

Effectiveness of defibrotide in the prevention of hepatic venooclusive disease among adult patients receiving allogeneic hematopoietic cell transplantation: A retrospective single center experience

Hepatic veno-occlusive disease/sinusoidal obstruction syndrome (VOD/SOS) is one of the most life-threatening early complications following hematopoietic cell transplantation (HCT). Due to the high mortality rate of severe VOD/SOS accompanied with multiorgan failure, there is a great interest in preventive strategies. The efficacy of defibrotide (DF) on the prevention of VOD/SOS has been clearly shown in high-risk pediatric patients, but evidence-based data on adults is scarce. In this report, we aimed to assess the impact of DF on the incidence of VOD/SOS in our center by posttransplant day 30 among patients who were treated with allogeneic HCT (allo?HCT). The study included a total of 56 patiens (28 males, 28 females). The median age of the study cohort was 43 (20?68). The daily dose of DF was 10 mg/kg and 25 mg/kg in 53 (94.6 %) and 3 (5.3 %) patients, respectively. Patients also recieved oral ursodeoxycolic acid (UDCA) 250 mg three-times daily started with conditioning until D + 90. Twenty-three (41.1 %) patients had at least one major EBMT-defined risk factor for development of VOD/SOS. One patient who belonged to a very high-risk group (with at least two major risk factors) developed very-severe VOD/SOS at posttransplant D + 20 and died as a result of multiorgan failure. The cumulative incidence of VOD/SOS at D + 30 was 1.9 %. Our findings indicate that 10 mg/kg daily intravenous DF combined with UDCA is quite effective in prevention of VOD/SOS in patients who underwent first allo-HSCT. © 202

Production of citric and isocitric acid by Yarrowia lipolytica strains grown on different carbon sources [Farklı karbon kaynakları üzerinde büyüyen Yarrowia lipolytica suşları tarafından sitrik ve izositrik asidin üretimi]

Objective: The goal of this study was to determine the influence of various carbon sources on the citric and isocitric acid production by various Yarrowia lipolytica strains.Methods: The yeasts used in our study were first investigated for organic acid production using screening media. Then, the effect of several complex carbon sources on the citric and isocitric acid production of selected yeast strains was investigated. The amount of citric and isocitric acid production was determined via enzymatic reactions.Results: In this study, 22 Y. lipolytica strains were investigated for the organic acid production. Among these strains, 2 strains (TEM YL 3 and TEM YL 20) were found to be highest organicacid producer. Taken all results together, the highest amounts of citric acid (66.2 g/L for TEM YL 3, 50.0 g/L for TEM YL 20) were observed in the production medium containing sunflower oil.Conclusion: Citric acid consumption, and thus, the need for it are constantly rising in our country, which imports citric acid. Therefore, in order to meet this need, further studies which will yield to the maximum citric acid production should be performed by utilizing waste carbon sources and by using new low-cost but high citric acid-producing strains. © 2014, Turkish Biochemistry Society. All rights reserved

'Natural Conduit' between two atria associated with atrial septal defect

PubMedID: 16047117Herein, we present a case of 46 years old woman with an extracardiac venous connection between two atria associated with secundum type atrial septal defect (ASD). This interatrial tunnel was not recognized by both transthoracic and transesophageal echocardiographic examinations. Computed tomography suspected a blood flow from right inferior pulmonary vein to inferior caval vein. Consequently, the patient underwent cardiac catheterization. Angiography revealed a tunnel between left and right atrium. To our knowledge, this is the first report of a case with venous tunnel between two atria associated with secundum type ASD in the literature. © Springer 2005

Multi-aspect analysis of ureteral access sheath usage in retrograde intrarenal surgery: Results of propensity score matching study

[No Abstract Available

Aortic dissection: Two years clinical experience of patients diagnosed with aortic dissection in a university emergency department

Giriş: Aort diseksiyonu hızlı tanı ve tedavi gerektiren mortalitesi yüksek kardiyovasküler bir hastalıktır. Acil serviste doğru ve erken tanı konulması ile uygun tedavinin yapılması prognoz açısından oldukça önemlidir. Ancak geliş şikayetlerinin nonspesifik olması nedeniyle tanıdaki en önemli unsur aort diseksiyonunun akla getirilmesidir. Gereç ve Yöntem: Bu çalışmada, Çukurova Üniversitesi Tıp Fakültesi Acil Tıp Anabilim Dalına Mart 2001 ile Mart 2003 tarihleri arasında başvuran ve aort diseksiyonu tanısı konulan 22 hasta geriye dönük olarak değerlendirildi. De Bakey sınıflandırması kullanılarak hastalar 3 gruba ayrıldı. Bulgular: Çalışmaya 4'ü kadın, 18'i erkek toplam 22 hasta alındı. Ortalama yaşları ise 57.5±8.3 yıldı. Has­taların 10'unda (%45.5) Tip 1, 4'ünde (%18.2) Tip 2, 8'inde (%36.4) Tip 3 diseksiyon saptandı. Tip 1 di-seksiyon olan hastaların %70'inde göğüs ağrısı mevcut iken, karın ağrısı şikayeti olan hastaların tümü tip 3 diseksiyon tanısı aldı. Disekan aort anevrizma tanısı konulan bu 22 hastanın 7'si operasyonu kabul etme­di. Tip 3 diseksiyona sahip hastaların 2'sine yapılan tetkikler sonrasında medikal tedavi önerildi. Cerrahi iş­lem uygulanan hastalardan 2'si preoperatif, 1 'i perioperatif ve 2'si postoperatif ex oldu. Cerrahi uygulanan 13 hastadan sadece 4'ü başarılı bir operasyon sonrası taburcu edildi. Sonuç: Sonuç olarak ülkemizde aort diseksiyonu halen mortalitesi yüksek bir hastalıktır. Bu hastalara acil serviste erken tanı koyulmalı ve en kısa sürede tedavilerine başlanmalıdır..Introduction: Aortic dissection is a cardiovascular disease with high mortality requiring quick diagnosis and treatment. Not only accurate but also early diagnosis and treatment in the emergency department is important because of the poor prognosis. Because of nonspecific complaints of the patients on admis­sion, the most important factor in diagnosing aortic dissection is to remind it as a differential diagnosis. Material and Method: In this study, 22 patients diagnosed with aortic dissection in the emergency de­partment during March I, 2001 and March 31, 2003 were evaluated. Patients were divided into three groups by using the De Bakey classification. Results: Twenty two patients (18 females, 4 females; mean age: 57.5±8.3 years) were included into the study. Ten of the patients had type one (45.5%), four of them had type 2 (18.2%), 8 of the patients had type 3 (36.4%) aortic dissection. Chest pain was the most complaint (70%) in patients with type 1 dissec­tion. However, in all of the patients with type 3 dissection, the complaint was the abdominal pain. Seven of the 22 patients did not accept to undergo an operation. Two of the patients with type 3 dissection were treated as medically. Two patients died during the preoperative period, 1 patient died during the operation and two patients were died during the postoperative period. Four patients were discharged af­ter a successful operation. Conclusion: As a result, aortic dissection is still a high-mortality illness. These patients should not only be evaluated and diagnosed quickly but also treated as soon as possible

Aortic dissection: Two years clinical experience of patients diagnosed with aortic dissection in a university emergency department

Giriş: Aort diseksiyonu hızlı tanı ve tedavi gerektiren mortalitesi yüksek kardiyovasküler bir hastalıktır. Acil serviste doğru ve erken tanı konulması ile uygun tedavinin yapılması prognoz açısından oldukça önemlidir. Ancak geliş şikayetlerinin nonspesifik olması nedeniyle tanıdaki en önemli unsur aort diseksiyonunun akla getirilmesidir. Gereç ve Yöntem: Bu çalışmada, Çukurova Üniversitesi Tıp Fakültesi Acil Tıp Anabilim Dalına Mart 2001 ile Mart 2003 tarihleri arasında başvuran ve aort diseksiyonu tanısı konulan 22 hasta geriye dönük olarak değerlendirildi. De Bakey sınıflandırması kullanılarak hastalar 3 gruba ayrıldı. Bulgular: Çalışmaya 4'ü kadın, 18'i erkek toplam 22 hasta alındı. Ortalama yaşları ise 57.5±8.3 yıldı. Has­taların 10'unda (%45.5) Tip 1, 4'ünde (%18.2) Tip 2, 8'inde (%36.4) Tip 3 diseksiyon saptandı. Tip 1 di-seksiyon olan hastaların %70'inde göğüs ağrısı mevcut iken, karın ağrısı şikayeti olan hastaların tümü tip 3 diseksiyon tanısı aldı. Disekan aort anevrizma tanısı konulan bu 22 hastanın 7'si operasyonu kabul etme­di. Tip 3 diseksiyona sahip hastaların 2'sine yapılan tetkikler sonrasında medikal tedavi önerildi. Cerrahi iş­lem uygulanan hastalardan 2'si preoperatif, 1 'i perioperatif ve 2'si postoperatif ex oldu. Cerrahi uygulanan 13 hastadan sadece 4'ü başarılı bir operasyon sonrası taburcu edildi. Sonuç: Sonuç olarak ülkemizde aort diseksiyonu halen mortalitesi yüksek bir hastalıktır. Bu hastalara acil serviste erken tanı koyulmalı ve en kısa sürede tedavilerine başlanmalıdır..Introduction: Aortic dissection is a cardiovascular disease with high mortality requiring quick diagnosis and treatment. Not only accurate but also early diagnosis and treatment in the emergency department is important because of the poor prognosis. Because of nonspecific complaints of the patients on admis­sion, the most important factor in diagnosing aortic dissection is to remind it as a differential diagnosis. Material and Method: In this study, 22 patients diagnosed with aortic dissection in the emergency de­partment during March I, 2001 and March 31, 2003 were evaluated. Patients were divided into three groups by using the De Bakey classification. Results: Twenty two patients (18 females, 4 females; mean age: 57.5±8.3 years) were included into the study. Ten of the patients had type one (45.5%), four of them had type 2 (18.2%), 8 of the patients had type 3 (36.4%) aortic dissection. Chest pain was the most complaint (70%) in patients with type 1 dissec­tion. However, in all of the patients with type 3 dissection, the complaint was the abdominal pain. Seven of the 22 patients did not accept to undergo an operation. Two of the patients with type 3 dissection were treated as medically. Two patients died during the preoperative period, 1 patient died during the operation and two patients were died during the postoperative period. Four patients were discharged af­ter a successful operation. Conclusion: As a result, aortic dissection is still a high-mortality illness. These patients should not only be evaluated and diagnosed quickly but also treated as soon as possible