Extended grazing: A detailed analysis of Irish dairy farms

Profitability and factors affecting grazing season length were econometrically analyzed using a representative sample of Irish dairy farms. The objective of this study was to explore what potential exists on Irish dairy farms to extend the grazing season and to quantify the possible economic benefits that result from lengthening the grazing season. Regression results indicate that location factors affect the length of the grazing season, but even when physical factors are controlled, farmer characteristics, such as education, also affect the grazing season length. The results of a panel data analysis show that significant cost reductions can be achieved by extending the grazing season. Overall, the findings indicate that lengthening the grazing season offers a cost-saving alternative on many Irish dairy farms, which could contribute to strengthening the competitiveness of the Irish dairy sector

Performance of LPG Storage Tanks on Ground Improved by Stone Columns

This paper describes the construction of four large tanks on poor soil conditions consisting of hydraulic fill placed over estuarine silt in Dublin port. The limited differential settlement that could be tolerated by the tanks required that they could not be placed on the existing ground. The optimum solution was found to be ground treatment using vibro-replacement with the formation of stone columns and compaction of the fill. The paper describes the design method used and the control tests. The predicted settlements are compared with settlement readings of the tanks following construction. These show that the chosen solution has performed well and satisfied the design requirements

What Supplementation Type for Spring Calving Dairy Cows at Grass in Autumn?

In spring-calving herds the requirement for conserved forages for indoor feeding is very limited but these feeds may have a role to play as buffer feeds in the spring and autumn periods when grass supply is less than required or as alternatives to concentrates on pasture for cows in early lactation. The objective of this experiment was to compare alternative forages and concentrates as buffer feeds on pasture with spring-calving cows in the autumn

Internet Use by Older Adults with Bipolar Disorder: International Survey Results

Background: The world population is aging and the number of older adults with bipolar disorder is increasing. Digital technologies are viewed as a framework to improve care of older adults with bipolar disorder. This analysis quantifies Internet use by older adults with bipolar disorder as part of a larger survey project about information seeking. Methods: A paper-based survey about information seeking by patients with bipolar disorder was developed and translated into 12 languages. The survey was anonymous and completed between March 2014 and January 2016 by 1222 patients in 17 countries. All patients were diagnosed by a psychiatrist. General estimating equations were used to account for correlated data. Results: Overall, 47% of older adults (age 60 years or older) used the Internet versus 87% of younger adults (less than 60 years). More education and having symptoms that interfered with regular activities increased the odds of using the Internet, while being age 60 years or older decreased the odds. Data from 187 older adults and 1021 younger adults were included in the analysis excluding missing values. Conclusions: Older adults with bipolar disorder use the Internet much less frequently than younger adults. Many older adults do not use the Internet, and technology tools are suitable for some but not all older adults. As more health services are only available online, and more digital tools are developed, there is concern about growing health disparities based on age. Mental health experts should participate in determining the appropriate role for digital tools for older adults with bipolar disorder

An Expanded Evaluation of Protein Function Prediction Methods Shows an Improvement In Accuracy

Background: A major bottleneck in our understanding of the molecular underpinnings of life is the assignment of function to proteins. While molecular experiments provide the most reliable annotation of proteins, their relatively low throughput and restricted purview have led to an increasing role for computational function prediction. However, assessing methods for protein function prediction and tracking progress in the field remain challenging. Results: We conducted the second critical assessment of functional annotation (CAFA), a timed challenge to assess computational methods that automatically assign protein function. We evaluated 126 methods from 56 research groups for their ability to predict biological functions using Gene Ontology and gene-disease associations using Human Phenotype Ontology on a set of 3681 proteins from 18 species. CAFA2 featured expanded analysis compared with CAFA1, with regards to data set size, variety, and assessment metrics. To review progress in the field, the analysis compared the best methods from CAFA1 to those of CAFA2. Conclusions: The top-performing methods in CAFA2 outperformed those from CAFA1. This increased accuracy can be attributed to a combination of the growing number of experimental annotations and improved methods for function prediction. The assessment also revealed that the definition of top-performing algorithms is ontology specific, that different performance metrics can be used to probe the nature of accurate predictions, and the relative diversity of predictions in the biological process and human phenotype ontologies. While there was methodological improvement between CAFA1 and CAFA2, the interpretation of results and usefulness of individual methods remain context-dependent

Finishing the euchromatic sequence of the human genome

The sequence of the human genome encodes the genetic instructions for human physiology, as well as rich information about human evolution. In 2001, the International Human Genome Sequencing Consortium reported a draft sequence of the euchromatic portion of the human genome. Since then, the international collaboration has worked to convert this draft into a genome sequence with high accuracy and nearly complete coverage. Here, we report the result of this finishing process. The current genome sequence (Build 35) contains 2.85 billion nucleotides interrupted by only 341 gaps. It covers ∼99% of the euchromatic genome and is accurate to an error rate of ∼1 event per 100,000 bases. Many of the remaining euchromatic gaps are associated with segmental duplications and will require focused work with new methods. The near-complete sequence, the first for a vertebrate, greatly improves the precision of biological analyses of the human genome including studies of gene number, birth and death. Notably, the human enome seems to encode only 20,000-25,000 protein-coding genes. The genome sequence reported here should serve as a firm foundation for biomedical research in the decades ahead

Welfare reforms and the Refugee Resettlement Strategy: An opportunity to achieve meaningful employment outcomes for New Zealanders from refugee backgrounds?

Despite employment being consistently identified as a key factor in successful refugee resettlement, people from refugee backgrounds in Aotearoa New Zealand are overrepresented in unemployment statistics. Of those who do gain employment, few secure work that is adequately remunerated and commensurate with the person\u27s skills and qualifications. This paper explores whether the two recent government-driven initiatives, the welfare reforms and the New Zealand Refugee Resettlement Strategy, provide an opportunity to address these issues. Based on previous research, the authors identify the main employment barriers facing people from refugee backgrounds. They argue that while the welfare reforms and the Refugee Resettlement Strategy are underpinned by a desire to see more people in employment, for real change to occur, an integrated holistic approach is needed. This approach needs to include additional resourcing for government-funded specialist one-on-one employment programmes that are available in all regions where refugees are resettled. These programmes combined with access to fully funded English language tuition and work experience and internship opportunities would help reduce the barriers people from refugee backgrounds face when seeking employment

Extended grazing: A detailed analysis of Irish dairy farms

Profitability and factors affecting grazing season length were econometrically analyzed using a representative sample of Irish dairy farms. The objective of this study was to explore what potential exists on Irish dairy farms to extend the grazing season and to quantify the possible economic benefits that result from lengthening the grazing season. Regression results indicate that location factors affect the length of the grazing season, but even when physical factors are controlled, farmer characteristics, such as education, also affect the grazing season length. The results of a panel data analysis show that significant cost reductions can be achieved by extending the grazing season. Overall, the findings indicate that lengthening the grazing season offers a cost-saving alternative on many Irish dairy farms, which could contribute to strengthening the competitiveness of the Irish dairy sector