Comprehensive HIV care and Anti-Retroviral Therapy in a conflict setting-outcomes, experiences, and lessons learned from Bukavu, Democratic Republic of Congo

2006 AIDS Conference in Toront

On the Role of Engagement in Information Seeking Contexts: From Research to Implementation

This workshop will provide a forum for researchers, practitioners and developers interested in user engagement and emotion in the context of information systems design and use. Specifically, we seek to address questions such as “How do we ensure that the measurement of subjective user experiences is robust and scalable?”, “How do we design for engaging and emotionally compelling experiences?”, and “How do we prevent disengagement?” The ability to answer these questions relies upon: a solid conceptual understanding of subjective experiences; robust, scalable approaches to measuring engagement; and the ability to utilize this knowledge in information systems design. This three-part workshop will include: talks by the organizers to ground the workshop’s themes; position paper presentations and design exemplars from attendees, and an interactive session focused on design scenarios and prototyping. The intersection of emotion and engagement with measurement and design in information seeking contexts is a timely issue for the iSchool community.ye

Rhythms of Everyday Life in Mobile Information Seeking: Reflections on a Photo-Diary Study

This work explores embodied mobile information practices through a photo-diary and interview study with nineteen smartphone users. We qualitatively analyze 234 diary entries and one hundred descriptions of diary entries to explore how mobile devices, specifically smartphones, facilitate embodied information seeking and production, drawing insights about the use of mobile devices as nonverbal communication tools. In addition, we probe the notion of smart-phones as an extension of the human body, and ways in which the affordances of these devices (e.g., portability, convenience) support and interrupt information practices. In particular, we observe that mobile devices are not only perceived as extensions of the mind and body, but are embedded in bodily rhythms and routines. This research extends empirical work in Library and Information Science (LIS), which has not focused extensively on mobile information practices in connection with the body, and suggests that the theoretical lens of embodiment may inform future work on mobile information practices

Psycho-physiological Methods in Information Science: Fit or Fad?

This interactive session focuses on the use of psycho-physiological methods in information science research. Through presentations, demos, and interactive discussion we will discuss and observe pragmatic issues of implementing these methods in IS and analyzing the data they generate. We will also examine the “fit” of these methods of measuring IS concepts and phenomenon, their reliability and validity, and the need for greater knowledge exchange amongst IS researchers to guide the effective use of these methods.ye

Drivers of octopus abundance and density in an anchialine lake: a 30 year comparison

Anchialine systems are isolated from the sea and often support species’ populations distinct from their marine counterparts. Sweetings Pond, an anchialine lake on the island of Eleuthera in The Bahamas was identified as a site of high Caribbean reef octopus, Octopus briareus (Robson, 1929) density, relative to coastal populations. However, observed deterioration in local benthic habitat and increased anthropogenic influence over the last 30 years imply that this octopus population may have undergone density and distribution shifts in response to these changing conditions. Here, we assess the system wide octopus density to provide an updated estimate. We hypothesize that despite depressed habitat availability in the 1980s, it will now support octopus densities less than historical estimates because of increasing human impact on the system. Drivers of abundance were also modelled, testing ecological hypotheses of the relationship between octopus count and prey, habitat coverage, and human disturbance. Octopus briareus were found in 7 of 27 of surveys with a mean survey count of 0.630 ± 1.25 per 900 m2. Octopus density did not vary significantly between sites. Octopus count was predicted to increase with increasing cover of calcareous rubble and the density of a preferred prey species, and intriguingly, counts decreased as a function of natural den abundance. System wide octopus density was comparable to earlier studies from the 1980s (1982 = 717.38 per km2; 1983 = 282.59 per km2; 2019 = 643.81 per km2) with no significant difference between years. Given the ecosystem’s unique and closed ecological community and the population dynamics and distribution drivers we present, Sweetings Pond has the potential to act as a ‘natural laboratory’ to explore further questions about marine insular systems and their influence on species populations in terms of ecological and behavioural change

Integrated collaborative care teams to enhance service delivery to youth with mental health and substance use challenges : Protocol for a pragmatic randomised controlled trial

Introduction: Among youth, the prevalence of mental health and addiction (MHA) disorders is roughly 20%, yet youth are challenged to access evidence-based services in a timely fashion. To address MHA system gaps, this study tests the benefits of an Integrated Collaborative Care Team (ICCT) model for youth with MHA challenges. A rapid, stepped-care approach geared to need in a youth-friendly environment is expected to result in better youth MHA outcomes. Moreover, the ICCT approach is expected to decrease service wait-times, be more youth-friendly and familyfriendly, and be more cost-effective, providing substantial public health benefits. Methods and analysis: In partnership with four community agencies, four adolescent psychiatry hospital departments, youth and family members with lived experience of MHA service use, and other stakeholders, we have developed an innovative model of collaborative, community-based service provision involving rapid access to needs-based MHA services. A total of 500 youth presenting for hospital-based, outpatient psychiatric service will be randomised to ICCT services or hospital-based treatment as usual, following a pragmatic randomised controlled trial design. The primary outcome variable will be the youth's functioning, assessed at intake, 6 months and 12 months. Secondary outcomes will include clinical change, youth/family satisfaction and perception of care, empowerment, engagement and the incremental cost-effectiveness ratio (ICER). Intent-to-treat analyses will be used on repeated-measures data, along with cost-effectiveness and cost-utility analyses, to determine intervention effectiveness. Ethics and dissemination: Research Ethics Board approval has been received from the Centre for Addiction and Mental Health, as well as institutional ethical approval from participating community sites. This study will be conducted according to Good Clinical Practice guidelines. Participants will provide informed consent prior to study participation and data confidentiality will be ensured. A data safety monitoring panel will monitor the study. Results will be disseminated through community and peer-reviewed academic channels

Dravet syndrome patient‐derived neurons suggest a novel epilepsy mechanism

Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/99647/1/ana23897.pd

Broad geographic sampling reveals the shared basis and environmental correlates of seasonal adaptation in Drosophila.

To advance our understanding of adaptation to temporally varying selection pressures, we identified signatures of seasonal adaptation occurring in parallel among Drosophila melanogaster populations. Specifically, we estimated allele frequencies genome-wide from flies sampled early and late in the growing season from 20 widely dispersed populations. We identified parallel seasonal allele frequency shifts across North America and Europe, demonstrating that seasonal adaptation is a general phenomenon of temperate fly populations. Seasonally fluctuating polymorphisms are enriched in large chromosomal inversions, and we find a broad concordance between seasonal and spatial allele frequency change. The direction of allele frequency change at seasonally variable polymorphisms can be predicted by weather conditions in the weeks prior to sampling, linking the environment and the genomic response to selection. Our results suggest that fluctuating selection is an important evolutionary force affecting patterns of genetic variation in Drosophila

Impact of a Randomized Campus/Community Trial to Prevent High-Risk Drinking Among College Students

High-risk drinking by college students continues to pose a significant threat to public health. Despite increasing evidence of the contribution of community-level and campus-level environmental factors to high risk drinking, there have been few rigorous tests of interventions that focus on changing these interlinked environments. The Study to Prevent Alcohol Related Consequences (SPARC) assessed the efficacy of a comprehensive intervention using a community organizing approach to implement environmental strategies in and around college campuses. The goal of SPARC was to reduce high-risk drinking and alcohol-related consequences among college students