Models of Consensus for Multiple Agent Systems

Models of consensus are used to manage multiple agent systems in order to choose between different recommendations provided by the system. It is assumed that there is a central agent that solicits recommendations or plans from other agents. That agent the n determines the consensus of the other agents, and chooses the resultant consensus recommendation or plan. Voting schemes such as this have been used in a variety of domains, including air traffic control. This paper uses an analytic model to study the use of consensus in multiple agent systems. The binomial model is used to study the probability that the consensus judgment is correct or incorrect. That basic model is extended to account for both different levels of agent competence and unequal prior odds. The analysis of that model is critical in the investigation of multiple agent systems, since the model leads us to conclude that in some cases consensus judgment is not appropriate. In addition, the results allow us to determine how many agents should be used to develop consensus decisions, which agents should be used to develop consensus decisions and under which conditions the consensus model should be used.Comment: Appears in Proceedings of the Tenth Conference on Uncertainty in Artificial Intelligence (UAI1994

Vevacious: A Tool For Finding The Global Minima Of One-Loop Effective Potentials With Many Scalars

Several extensions of the Standard Model of particle physics contain additional scalars implying a more complex scalar potential compared to that of the Standard Model. In general these potentials allow for charge and/or color breaking minima besides the desired one with correctly broken SU(2)_L times U(1)_Y . Even if one assumes that a metastable local minimum is realized, one has to ensure that its lifetime exceeds that of our universe. We introduce a new program called Vevacious which takes a generic expression for a one-loop effective potential energy function and finds all the tree-level extrema, which are then used as the starting points for gradient-based minimization of the one-loop effective potential. The tunneling time from a given input vacuum to the deepest minimum, if different from the input vacuum, can be calculated. The parameter points are given as files in the SLHA format (though is not restricted to supersymmetric models), and new model files can be easily generated automatically by the Mathematica package SARAH. This code uses HOM4PS2 to find all the minima of the tree-level potential, PyMinuit to follow gradients to the minima of the one-loop potential, and CosmoTransitions to calculate tunneling times.Comment: 44 pages, 1 figure, manual for publicly available software, v2 corresponds to version accepted for publication in EPJC [clearer explanation of scale dependence and region of validity, explicit mention that SLHA files should have blocks matching those expected by model files, updated references

Validity of the CMSSM interpretation of the diphoton excess

It has been proposed that the observed diphoton excess at 750 GeV could be explained within the constrained minimal supersymmetric standard model via resonantly produced stop bound states. We reanalyze this scenario critically and extend previous work to include the constraints from the stability of the electroweak vacuum and from the decays of the stoponium into a pair of Higgs bosons. It is shown that the interesting regions of parameter space with a light stop and Higgs of the desired mass are ruled out by these constraints. This conclusion is not affected by the presence of the bound states because the binding energy is usually very small in the regions of parameter space which can explain the Higgs mass. Thus, this also leads to strong constraints on the diphoton production cross section which is in general too small.Comment: 8 pages, 5 figures; v2: added Fig. 5, matches published versio

Neural regulation of cardiovascular response to exercise: role of central command and peripheral afferents

During dynamic exercise, mechanisms controlling the cardiovascular apparatus operate to provide adequate oxygen to fulfill metabolic demand of exercising muscles and to guarantee metabolic end-products washout. Moreover, arterial blood pressure is regulated to maintain adequate perfusion of the vital organs without excessive pressure variations. The autonomic nervous system adjustments are characterized by a parasympathetic withdrawal and a sympathetic activation. In this review, we briefly summarize neural reflexes operating during dynamic exercise. The main focus of the present review will be on the central command, the arterial baroreflex and chemoreflex, and the exercise pressure reflex. The regulation and integration of these reflexes operating during dynamic exercise and their possible role in the pathophysiology of some cardiovascular diseases are also discusse

Constraining the Natural MSSM through tunneling to color-breaking vacua at zero and non-zero temperature

We re-evaluate the constraints on the parameter space of the minimal supersymmetric standard model from tunneling to charge- and/or color-breaking minima, taking into account thermal corrections. We pay particular attention to the region known as the Natural MSSM, where the masses of the scalar partners of the top quarks are within an order of magnitude or so of the electroweak scale. These constraints arise from the interaction between these scalar tops and the Higgs fields, which allows the possibility of parameter points having deep charge- and color-breaking true vacua. In addition to requiring that our electro-weak-symmetry-breaking, yet QCD- and electromagnetism-preserving vacuum has a sufficiently long lifetime at zero temperature, also demanding stability against thermal tunneling further restricts the allowed parameter space.Comment: 7 pages, 2 figures, software available from http://vevacious.hepforge.org/ - version 2 matches that accepted for publication in Phys. Lett.

Real-time assembly of ribonucleoprotein complexes on nascent RNA transcripts.

Cellular protein-RNA complexes assemble on nascent transcripts, but methods to observe transcription and protein binding in real time and at physiological concentrations are not available. Here, we report a single-molecule approach based on zero-mode waveguides that simultaneously tracks transcription progress and the binding of ribosomal protein S15 to nascent RNA transcripts during early ribosome biogenesis. We observe stable binding of S15 to single RNAs immediately after transcription for the majority of the transcripts at 35 °C but for less than half at 20 °C. The remaining transcripts exhibit either rapid and transient binding or are unable to bind S15, likely due to RNA misfolding. Our work establishes the foundation for studying transcription and its coupled co-transcriptional processes, including RNA folding, ligand binding, and enzymatic activity such as in coupling of transcription to splicing, ribosome assembly or translation