TP53 regulates human AlkB homologue 2 expression in glioma resistance to Photofrin-mediated photodynamic therapy

2010-2011 > Academic research: refereed > Publication in refereed journa

Contemporary management of cancer of the oral cavity

Oral cancer represents a common entity comprising a third of all head and neck malignant tumors. The options for curative treatment of oral cavity cancer have not changed significantly in the last three decades; however, the work up, the approach to surveillance, and the options for reconstruction have evolved significantly. Because of the profound functional and cosmetic importance of the oral cavity, management of oral cavity cancers requires a thorough understanding of disease progression, approaches to management and options for reconstruction. The purpose of this review is to discuss the most current management options for oral cavity cancers

The depiction of size and shape in iconic gestures accompanying object descriptions in Anyi (Côte d’Ivoire) and in Dutch (The Netherlands)

Language Use in Past and Presen

Size and shape depictions in the manual modality: a taxonomy of iconic devices in Adamorobe Sign Language

Language Use in Past and Presen

Cross-linguistic diversity in spatial timelines: Evidence from sign language isolates

This paper discusses the expression of time through spatial means in village sign languages of Indonesia, Ghana, Thailand, and Mexico. In the urban signing varieties reported thus far, the typical timeline runs along the signer’s sagittal axis, and is split at the signer's centre, such that the area behind the signer represents the past, and the front of the signer represents the future. This paper shows that the front-back timeline may be the typologically prevalent structure, but it is not the only option, and time can be projected onto space in a number of different ways. The main timeline in Chican Village Sign Language (Mexico) projects the past onto the signing space in front of the signer, and the future is conceptualised above the signer's head. Both Adamorobe Sign Language (Ghana) and Ban Khor Sign Language (Thailand) have adopted a vertically oriented timeline, but representing time from bottom to top and top to bottom respectively. Kata Kolok signers (Bali) do not make use of any of the body-anchored timelines, and have adopted a celestial timeline, running from East to West instead. These findings indicate that the impact of the visual modality is limited in the conceptualisation of temporal relations in sign languages, and that sign languages may utilise each of the dimensions of signing space to express temporal relations. These preliminary reports suggest that village sign languages – being language isolates –may continue to make unique contributions to our understanding of the typological variation among sign languages