COVID-19 Pandemic: Questioning Conspiracy Theories, Beliefs or Claims that Have Potential Negative Impact on Public Health Interventions and Proposal for Integrated Communication and Information Dissemination Strategies (ICIDS)

The COVID-19 outbreak that started in Wuhan, China, in December 2019 spread across the world causing a pandemic that infected and killed thousands of people globally. Countries made frantic efforts to put in place measures to curb the spread of the viral infections. The measures included social distancing, regular washing of hands with soap, applying sanitizers to hands and surfaces, use of personal protective equipment, screening, testing, isolation of suspected cases, quarantine of cases, lockdowns, treatment of cases and controlled burial of deceased cases.Almost all affected countries experienced four main hindrances to their efforts to control the COVID-19 pandemic; (i) challenges in implementing preventative measures effectively, (ii) health care delivery systems that could not cope with the pandemic, (iii) limited resources, and (iv) negative socio-economic impact caused by the pandemic. One of the challenges that hindered efforts to prevent the spread of the pandemic or to manage it are various conspiracy theories, beliefs, and or unproven claims, some of which are contradictory, that were circulated across the world.2This article gives an overview of the covid-19 pandemic, some conspiracy theories, beliefs and claims that were circulated as unofficial information, and questions the unofficial information. The article ends with an outline of some potential negative impact of conspiracy theories, beliefs and claims on public health interventions aimed at controlling the pandemic. In order to counter disinformation and misinformation, the article recommends the establishment of well-coordinated Integrated Communication and Information Dissemination Strategies (ICIDS) at global, continental, regional and national levels

Postgraduate research methodological flaws detected at final examination stage: Who is to blame?

In the wake of globalisation, most universities are intensifying efforts to improve their overall performance in order to attract students and enhance chances of securing competitive funding from various sources. As part of these efforts, universities are striving to ensure that their postgraduate programmes meet nationally and internationally acceptable standards. Research projects conducted by students form a critical component of most postgraduate programmes and universities have put in place procedures meant to ensure that postgraduate research meets acceptable minimum standards. The procedures include setting minimum entry educational qualifications, supervision by qualified members of university academic staff, institutional evaluation of research proposals before the proposed research is embarked on, submission of progress reports by postgraduate students during the course of their programmes, and final examination of students’ theses, dissertations or research reports by internal as well as external examiners. In some instances, the examiners recommend outright rejection of the student’s write-up if they consider the methodology used to be inappropriate to answer research questions of the project conducted. The implications of research methodological shortcomings which are identified at the final examination stage, even if the research proposals were evaluated and approved by appropriate university structures before commencement of the research projects, are discussed. As postgraduate programmes are meant to nurture a competent and resourceful workforce and future researchers, universities need to pay attention to the issue of research methodology and internal evaluation systems in order to minimise chances of compromising the quality of their postgraduate degree programmes

Validation of a career guidance brochure for student nurses using the nominal group technique

BACKGROUND : Nursing is a career which, especially for male students, requires one making an informed choice prior to pursuing it. A mixed-method, qualitative study, investigating the professional socialization process of male student nurses in Malawi found that most students did not make an informed choice regarding their selected career. This resulted in some of them facing many challenges which compromised their academic performance, and in some cases, contributed to high attrition rates. An “unmet need” for career guidance was identified by the study participants. Further, the study participants made recommendations on the need to address the unmet need for career guidance. A brochure entitled “A career in nursing and midwifery in Malawi” was designed. This article reports on the validation of the brochure. OBJECTIVE : The goal of the study was to validate the brochure utilising the Nominal Group Technique. METHODS : The validation exercise was part of the mixed method study. Five steps of the Nominal Group Technique (NGT) were utilised, as expounded by Vigra-Atkins, aimed at evaluating the content contained in the brochure. Study participants in four nursing colleges (n = 37) participated by studying the draft brochure and identifying strong and weak areas for improvements. Responses were ranked based on group consensus. FINDINGS : A total of five groups were involved in NGT discussions. Four of the five groups found the brochure relevant and motivating to prospective students. However, two groups suggested that pictures needed to be more gender sensitive. CONCLUSION : Through the NGT, the brochure was commended by the majority of the participants as being clear and relevant in terms of giving information necessary for a nursing career choice. Finally, the authors recommend the use of the NGT compared to other group-based research techniques, considering the benefits the NGT offers.Nursing Education Initiative Partnership (NEPI) Malawi; Witwatersrand University Postgraduate Merit Awardhttps://www.annalsofglobalhealth.orghj2019Nursing Scienc

Ethics in occupational health : deliberations of an international workgroup addressing challenges in an African context

Background: International codes of ethics play an important role in guiding professional practice in developing countries. In the occupational health setting, codes developed by international agencies have substantial import on protecting working populations from harm. This is particularly so under globalisation which has transformed processes of production in fundamental ways across the globe. As part of the process of revising the Ethical Code of the International Commission on Occupational Health, an Africa Working Group addressed key challenges for the relevance and cogency of an ethical code in occupational health for an African context through an iterative consultative process. Discussion: Firstly, even in the absence of strong legal systems of enforcement, and notwithstanding the value of legal institutionalisation of ethical codes, guidelines alone may offer advantageous routes to enhancing ethical practice in occupational health. Secondly, globalisation has particularly impacted on health and safety at workplaces in Africa, challenging occupational health professionals to be sensitive to, and actively redress imbalance of power. Thirdly, the different ways in which vulnerability is exemplified in the workplace in Africa often places the occupational health professional in invidious positions of Dual Loyalty. Fourth, the particular cultural emphasis in traditional African societies on collective responsibilities within the community impacts directly on how consent should be sought in occupational health practice, and how stigma should be dealt with, balancing individual autonomy with ideas of personhood that are more collective as in the African philosophy of ubuntu. To address stigma, practitioners need to be additionally sensitive to how power imbalances at the workplace intersect with traditional cultural norms related to solidarity. Lastly, particularly in the African context, the inseparability of workplace and community means that efforts to address workplace hazards demand that actions for occupational health extend beyond just the workplace. Summary: A stronger articulation of occupational health practice with advocacy for prevention should be an ethical norm. Ethical codes should ideally harmonize and balance individual and community needs so as to provide stronger moral authority guidelines. There is a need to consider an African Charter on Bioethics as complementary and strengthening of existing codes for the region

Human candidate gene polymorphisms and risk of severe malaria in children in Kilifi, Kenya: a case-control association study

Background: Human genetic factors are important determinants of malaria risk. We investigated associations between multiple candidate polymorphisms—many related to the structure or function of red blood cells—and risk for severe Plasmodium falciparum malaria and its specific phenotypes, including cerebral malaria, severe malaria anaemia, and respiratory distress. Methods: We did a case-control study in Kilifi County, Kenya. We recruited as cases children presenting with severe malaria to the high-dependency ward of Kilifi County Hospital. We included as controls infants born in the local community between Aug 1, 2006, and Sept 30, 2010, who were part of a genetics study. We tested for associations between a range of candidate malaria-protective genes and risk for severe malaria and its specific phenotypes. We used a permutation approach to account for multiple comparisons between polymorphisms and severe malaria. We judged p values less than 0·005 significant for the primary analysis of the association between candidate genes and severe malaria. Findings: Between June 11, 1995, and June 12, 2008, 2244 children with severe malaria were recruited to the study, and 3949 infants were included as controls. Overall, 263 (12%) of 2244 children with severe malaria died in hospital, including 196 (16%) of 1233 with cerebral malaria. We investigated 121 polymorphisms in 70 candidate severe malaria-associated genes. We found significant associations between risk for severe malaria overall and polymorphisms in 15 genes or locations, of which most were related to red blood cells: ABO, ATP2B4, ARL14, CD40LG, FREM3, INPP4B, G6PD, HBA (both HBA1 and HBA2), HBB, IL10, LPHN2 (also known as ADGRL2), LOC727982, RPS6KL1, CAND1, and GNAS. Combined, these genetic associations accounted for 5·2% of the variance in risk for developing severe malaria among individuals in the general population. We confirmed established associations between severe malaria and sickle-cell trait (odds ratio [OR] 0·15, 95% CI 0·11–0·20; p=2·61 × 10−58), blood group O (0·74, 0·66–0·82; p=6·26 × 10−8), and –α3·7-thalassaemia (0·83, 0·76–0·90; p=2·06 × 10−6). We also found strong associations between overall risk of severe malaria and polymorphisms in both ATP2B4 (OR 0·76, 95% CI 0·63–0·92; p=0·001) and FREM3 (0·64, 0·53–0·79; p=3·18 × 10−14). The association with FREM3 could be accounted for by linkage disequilibrium with a complex structural mutation within the glycophorin gene region (comprising GYPA, GYPB, and GYPE) that encodes for the rare Dantu blood group antigen. Heterozygosity for Dantu was associated with risk for severe malaria (OR 0·57, 95% CI 0·49–0·68; p=3·22 × 10−11), as was homozygosity (0·26, 0·11–0·62; p=0·002). Interpretation: Both ATP2B4 and the Dantu blood group antigen are associated with the structure and function of red blood cells. ATP2B4 codes for plasma membrane calcium-transporting ATPase 4 (the major calcium pump on red blood cells) and the glycophorins are ligands for parasites to invade red blood cells. Future work should aim at uncovering the mechanisms by which these polymorphisms can result in severe malaria protection and investigate the implications of these associations for wider health. Funding: Wellcome Trust, UK Medical Research Council, European Union, and Foundation for the National Institutes of Health as part of the Bill & Melinda Gates Grand Challenges in Global Health Initiative