Popular romance and the woman reader

'Popular Romance and the Woman Reader' is divided into three parts. The first is an analysis of theories of reading, of the woman reader and of how we read popular texts. The first section discusses women readers and popular romance in a Western context, with special reference to an American study by Janice Radway, Reading the Romance, and the second looks at how similar issues might apply amongst African women readers. Part II is a textual analysis of several romance texts. The final part is an account of four interviews in which black South African women talk about their romance reading. Although the focus of the study is on popular romance, I also intend it to re-examine the categories of 'woman reader' and 'black woman reader in South Africa'. As new freedoms are opened to the reader in South Africa, it is offered as a contribution to an understanding of how reading, and the construction of subjectivity itself, can be transformed in the future

Ligneous membranitis in Scottish terriers is associated with a single nucleotide polymorphism in the plasminogen (plg) gene

Ligneous membranitis (LM) is a rare chronic inflammatory condition of the mucous membranes associated with plasminogen (encoded by PLG) deficiency in affected humans and dogs. In human, the condition is genetic in nature with numerous mutations and polymorphisms in PLG identified in affected individuals and related family members. The condition is uncommonly reported in dogs and, to date, no genetic studies have been performed. We identified related Scottish Terriers (littermates) with severe LM and unaffected relatives (sire, dam and a sibling from a previous litter). Plasma plasminogen activity was below normal in one affected dog but within normal reference intervals for the other. Sequencing of PLG from the affected dogs revealed a homozygous A>T single nucleotide polymorphism in an intron donor site (c.1256+2T>A). The related, unaffected dogs displayed heterozygous alleles at this position (c.1256+2T/A), whereas no mutation was detected in unaffected, non‐related control dogs. This is the first report to identify gene polymorphisms associated with LM in dogs

Sifiso Mzobe’s Young Blood: Spaces of getting and becoming in post-apartheid Durban

Sifiso Mzobe’s Young blood (2010) generates much of its energy, this article will argue, through its representation of social and physical mobility and its articulation of space with modes of consumption in post-apartheid South Africa. The novel is set chiefly in the township of Umlazi, the city of Durban and some of its middle- class suburbs. The chief protagonist, a young car thief, moves between township, city and suburb with ease in stolen cars. The open space of the highway separates township and suburb, but also connects them. The novel shows how the spatial arrangements of power and control associated with apartheid are increasingly undermined and reconfigured by new practices of everyday life. Young blood suggests that a certain style of driving can offer new ways of inhabiting the South African city and of bringing its disparate parts together. The ability to move between places in the novel provides opportunities for upward mobility and also enables new forms of symbiosis, trade and consumption. Stealing and driving cars enable Sifiso and his friends to bridge the divide between township and suburb and turn the distance between the two places into a domain of attainment and performance. But the rapid upward social mobility that high-level criminal activity allows is exposed as uncertain and ephemeral by the end of the novel, and the slower route offered by education to self-improvement and class mobility is proffered in its place

Failure mechanism of the all-polyethylene glenoid implant

Fixation failure of glenoid components is the main cause of unsuccessful total shoulder arthroplasties. The characteristics of these failures are still not well understood, hence, attempts at improving the implant fixation are somewhat blind and the failure rate remains high. This lack of understanding is largely due to the fundamental problem that direct observations of failure are impossible as the fixation is inherently embedded within the bone. Twenty custom made implants, reflecting various common fixation designs, and a specimen set-up was prepared to enable direct observation of failure when the specimens were exposed to cyclic superior loads during laboratory experiments. Finite element analyses of the laboratory tests were also carried out to explain the observed failure scenarios. All implants, irrespective of the particular fixation design, failed at the implant-cement interface and failure initiated at the inferior part of the component fixation. Finite element analyses indicated that this failure scenario was caused by a weak and brittle implant-cement interface and tensile stresses in the inferior region possibly worsened by a stress raiser effect at the inferior rim. The results of this study indicate that glenoid failure can be delayed or prevented by improving the implant/cement interface strength. Also any design features that reduce the geometrical stress raiser and the inferior tensile stresses in general should delay implant loosening

Treatment of the fixation surface improves glenoid prosthesis longevity in-vitro

Many commercial cemented glenoid components claim superior fixation designs and increased survivability. However, both research and clinical studies have shown conflicting results and it is unclear whether these design variations do improve loosening rates. Part of the difficulty in investigating fixation failure is the inability to directly observe the fixation interface, a problem addressed in this study by using a novel experimental set-up.Cyclic loading-displacement tests were carried out on 60 custom-made glenoid prostheses implanted into a bone substitute. Design parameters investigated included treatment of the fixation surface of the component resulting in different levels of back-surface roughness, flat-back versus curved-back, keel versus peg and more versus less conforming implants. Visually-observed failure and ASTM-recommended rim-displacements were recorded throughout testing to investigate fixation failure and if rim displacement is an appropriate measure of loosening. Roughening the implant back (Ra > 3 µm) improved resistance to failure (P < 0.005) by an order of magnitude with the rough and smooth groups failing at 8712 ± 5584 cycles (mean ± SD) and 1080 ± 1197 cycles, respectively. All other design parameters had no statistically significant effect on the number of cycles to failure. All implants failed inferiorly and 95 % (57/60) at the implant/cement interface. Rim-displacement correlated with visually observed failure. The most important effect was that of roughening the implant, which strengthened the polyethylene-cement interface. Rim-displacement can be used as an indicator of fixation failure, but the sensitivity was insufficient to capture subtle effects.Level of Evidence: Basic Science Study, Biomechanical Analysis

Little perpetrators, witness-bearers and the young and the brave: towards a post-transitional aesthetics

The aesthetic choices characterizing work produced during the transition to democracy have been well documented. We are currently well into the second decade after the 1994 election - what then of the period referred to as the 'second transition'? Have trends consolidated, hardened, shifted, or have new 'post-transitional' trends emerged? What can be expected of the future 'born free' generation of writers and readers, since terms such as restlessness, dissonance and disjuncture are frequently used to describe the experience of constitutional democracy as it co-exists with the emerging new apartheid of poverty? Furthermore, what value is there in identifying post-transitional aesthetic trends?DHE

The impact of the SARS‐CoV‐2 pandemic and COVID‐19 on lung transplantation in the UK: Lessons learned from the first wave

BACKGROUND: Lung transplantation is particularly susceptible to the impact of the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) pandemic, and evaluation of changes to practice is required to inform future decision-making. METHODS: A retrospective review of the UK Transplant Registry (UKTR) and national survey of UK lung transplant centers has been performed. RESULTS: There was geographic variation in the prevalence of COVID-19 infection across the UK. The number of donors fell by 48% during the early pandemic period. Lung utilization fell to 10% (compared with 24% for the same period of 2019). The number of lung transplants performed fell by 77% from 53, March to May 2019, to 12. Seven (58%) of these were performed in a single-center, designated "COVID-light." The number of patients who died on the lung transplant waiting list increased, compared to the same period of 2019 (p = .0118). Twenty-six lung transplant recipients with confirmed COVID-19 infection were reported during the study period. CONCLUSION: As the pandemic continues, reviewing practice and implementing the lessons learned during this period, including the use of robust donor testing strategies and the provision of "COVID-light" hospitals, are vital in ensuring the safe continuation of our lung transplant program