Çok geç başlangıçlı "Trikotilomani": bir olgu sunumu

Trichotillomania is a chronic psychiatric disorder that repetitive hair pulling which leads to marked hair loss, negative effects on all areas of the person's functioning. Although trichotillomania has been known for many years, it has attracted less attention than other psychiatric disorders. Therefore, the information about its epidemiology, etiology, clinical feature and therapeutic approaches are limited. Trichotillomania usually begins in early childhood or adolescence. It is more common in women than men. Cases are frequently referred to the first dermatology outpatient clinics due to marked hair loss. Trichotillomania is one of the common issues of psychiatry and dermatology. In patients with trichotillomania, comorbid psychiatric disorders often accompany the clinical picture. The most common psychiatric comorbidities are mood disorders and anxiety disorders. In this study, we report a male patient who was treated with a diagnosis of very late onset trichotillomania with comorbid depression. The fact that trichotillomania started at an advanced age is a feature that makes our case interesting.Trikotilomani, yineleyen saç yolmalar sonucu belirgin saç kaybına yol açan, kişinin işlevselliğinin tüm alanlarını olumsuz etkileyen süregen seyirli bir ruhsal bozukluktur. Trikotilomani uzun yıllardır bilinmesine rağmen diğer ruhsal bozukluklardan daha az ilgi çekmiştir. Bu nedenle epidemiyolojisi, etiyolojisi, klinik görünümü ve tedavi yaklaşımları ile ilgili bilgiler sınırlıdır. Trikotilomani genellikle erken çocukluk ya da ergenlik döneminde başlar. Kadınlarda erkeklere göre daha sık görülmektedir. Belirgin saç kaybı nedeni ile olgular ilk kez dermatoloji polikliniklerine başvururlar. Trikotillomani psikiyatri ile dermatolojinin ortak konularından biridir. Trikotilomanili olgularda eş tanılı psikiyatrik bozukluklar da sıklıkla klinik tabloya eşlik eder. En yaygın görülen psikiyatrik eş tanılar duygudurum bozuklukları, anksiyete bozukluklarıdır. Bu çalışmada eştanılı depresyonu da olan çok geç başlangıçlı trikotillomani tanısı ile tedavisi düzenlenen bir erkek olgu sunulmuştur. Trikotillomaninin ileri yaşta başlamış olması olgumuzu ilginç kılan bir özelliktir

Cutaneous leiomyoma in a child: a case report

WOS: 000321003100012PubMed: 23599756Leiomyoma is a benign tumour commonly encountered in the genitourinary and gastrointestinal organs in adults. Cutaneous leiomyomas are rare benign tumors arising from the arrector pili muscle of hair follicles. Cutaneous leiomyomas are more likely to occur in adults than in children. We describe a case of a 10-year-old female who presented with multiple, firm, red-brown masses on the back. A punch biopsy was performed. Under high-power examination, spindle cells with an eosinophilic cytoplasm were observed and immunohistochemical studies were performed; the cells stained strongly positive for smooth muscle actin (SMA). the patient was subsequently diagnosed with pilar leiomyoma and referred to a plastic surgeon for surgical treatment. Although cutaneous leiomyoma is a rare disorder, we identified a case of pilar leiomyoma in a young female. A careful clinical assessment led to the correct diagnosis and therapy in the present case. We propose that leiomyoma ought to be considered in the differential diagnosis of any cutaneous or mucosal mass in children

The cytologic investigation of brow adipose tissue of D.laniger Felten Storch, 1968 Mammalia: Rodentia in hibernation

T his study was conducted on the D.laniger samples maintained in the laboratory condition after collecting from the natural environment. Investigations were performed in the experimental groups in the active period at the time of hibernation and at the period of intermediate awakening during hibernation. The brown adipose tissue BAT of these animals investigated was removed by dissection. The tissue samples dissected were prepared for the analysis at Transmission Electron Microscopy TEM and photographed. It was observed for the D. laniger BAT cells in the active period that there are high amount mitochondria and whereas the scarce amount of the lipid droplets. However, it was drawn attention to BAT cell of animals in hibernation that there plenty of capillary vessels and lipid droplets between them. The contact between lipid droplets with each other in the cytoplasm of animal at intermediate awakening in the winter during hibernation and cytoplasmic material loss and melting of mitochondria cristae partly were observed. These results of this study suggest that it may be useful to understand the importance of the brown adipose tissue of some hibernating mammal

Epidemiology of pemphigus in Turkey: One-year prospective study of 220 cases

Pemphigus is a group of rare and life-threatening autoimmune blistering diseases of the skin and mucous membranes. Although they occur worldwide, their incidence shows wide geographical variation, and prospective data on the epidemiology of pemphigus are very limited. Objective of this work is to evaluate the incidence and epidemiological and clinical features of patients with pemphigus in Turkey. All patients newly diagnosed with pemphigus between June 2013 and June 2014 were prospectively enrolled in 33 dermatology departments in 20 different provinces from all seven regions of Turkey. Disease parameters including demography and clinical findings were recorded. A total of 220 patients were diagnosed with pemphigus during the 1-year period, with an annual incidence of 4.7 per million people in Turkey. Patients were predominantly women, with a male to female ratio of 1:1.41. The mean age at onset was 48.9 years. Pemphigus vulgaris (PV) was the commonest clinical subtype (n=192; 87.3%), followed by pemphigus foliaceus (n=21; 9.6%). The most common clinical subtype of PV was the mucocutaneous type (n=83; 43.2%). The mean Pemphigus Disease Area Index was 28.14±22.21 (mean ± Standard Deviation).  The incidence rate of pemphigus in Turkey is similar to the countries of South-East Europe, higher than those reported for the Central and Northern European countries and lower than the countries around the Mediterranean Sea and Iran. Pemphigus is more frequent in middle-aged people and is more common in women. The most frequent subtype was PV, with a 9-fold higher incidence than pemphigus foliaceus.   </p

Hypertrichosis in Childhood

WOS: 000429662600002Hypertrichosis is more than normal and excessive hair growth according to individual's age and sex. in hypertrichosis, hair growth is not androgen dependent and does not include male type hair growth. Hypertrichosis differentiates from hirsutism with this feature. in this review, childhood hypertrichosis will be examined under two main headings as generalized hypertrichosis and localized hypertrichosis. Also, generalized hypertrichosis and localized hypertrichosis will be presented with congenital and acquired sub headings

Herpes Zoster in Two Healthy Children

Herpes zoster is an acute dermatomal viral infection caused by the reactivation of varicella zoster virus. The disease is commonly seen among elderly people and immunocompromised individuals, it is also rarely observed in immunocompetent children though. In this report, two herpes zoster cases with trigeminal-involvement in which no factors inducing the reactivation of the virus were detected are presented, as the disease is unusually seen during childhood

Hypertrichosis in Childhood

Hipertrikoz, bir bireyde yaşı ve cinsiyetine göre normalden fazla ve aşırı miktarda kıl büyümesidir. Hipertrikozda kıl büyümesi androjen bağımlı değildir ve erkek tipi kıl büyümesini içermez. Bu özelliği ile hirsutismustan ayrılır. Bu derlemede çocuklarda görülen hipertrikoz; generalize hipertrikoz ve lokalize hipertrikoz olmak üzere 2 ana başlık altında incelenecektir. Ayrıca generalize hipertrikoz ve lokalize hipertrikoz; konjenital ve akiz alt başlıkları altında sunulacaktır.Hypertrichosis is more than normal and excessive hair growth according to individual's age and sex. In hypertrichosis, hair growth is not androgen dependent and does not include male type hair growth. Hypertrichosis differentiates from hirsutism with this feature. In this review, childhood hypertrichosis will be examined under two main headings as generalized hypertrichosis and localized hypertrichosis. Also, generalized hypertrichosis and localized hypertrichosis will be presented with congenital and acquired sub headings