4,347 research outputs found

    Supergravity duals of gauge theories from F(4) gauged supergravity in six dimensions

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    We construct supergravity solutions dual to twisted field theories that are the worldvolume theories of D4-branes wrapped on 2, 3-cycles, and NS-fivebranes on 3-cycles. We first obtain the solutions for the Romans' six-dimensional gauged supergravity theories and then up-lift them to ten dimensions. In particular, we find solutions for field configurations with either non-Abelian fields or B-fields being excited. One of these solutions, in the massless case, is up-lifted to the massless type IIA string theory. This is the first example of such a kind. The cases studied provide new examples of the AdS/CFT duality involving twisted field theories.Comment: 26 pages, 3 figures, minor changes and references added to match the published versio

    A biophysically accurate floating point somatic neuroprocessor

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    Model of Low-pass Filtering of Local Field Potentials in Brain Tissue

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    Local field potentials (LFPs) are routinely measured experimentally in brain tissue, and exhibit strong low-pass frequency filtering properties, with high frequencies (such as action potentials) being visible only at very short distances (≈\approx10~ÎŒm\mu m) from the recording electrode. Understanding this filtering is crucial to relate LFP signals with neuronal activity, but not much is known about the exact mechanisms underlying this low-pass filtering. In this paper, we investigate a possible biophysical mechanism for the low-pass filtering properties of LFPs. We investigate the propagation of electric fields and its frequency dependence close to the current source, i.e. at length scales in the order of average interneuronal distance. We take into account the presence of a high density of cellular membranes around current sources, such as glial cells. By considering them as passive cells, we show that under the influence of the electric source field, they respond by polarisation, i.e., creation of an induced field. Because of the finite velocity of ionic charge movement, this polarization will not be instantaneous. Consequently, the induced electric field will be frequency-dependent, and much reduced for high frequencies. Our model establishes that with respect to frequency attenuation properties, this situation is analogous to an equivalent RC-circuit, or better a system of coupled RC-circuits. We present a number of numerical simulations of induced electric field for biologically realistic values of parameters, and show this frequency filtering effect as well as the attenuation of extracellular potentials with distance. We suggest that induced electric fields in passive cells surrounding neurons is the physical origin of frequency filtering properties of LFPs.Comment: 10 figs, revised tex file and revised fig

    Changes in the carbon balance of tropical forest: evidence from long-term plots

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    The role of the world’s forests as a “sink” for atmospheric carbon dioxide is the subject of active debate. Long-term monitoring of plots in mature humid tropical forests concentrated in South America revealed that biomass gain by tree growth exceeded losses from tree death in 38 out of 50 neotropical sites. These forest plots have accumulated 0.71 + 0.34 tons of carbon per hectare per year in recent decades. The data suggest that neotropical forests may be a significant carbon sink, reducing the rate of increase in atmospheric CO2

    Antimicrobial resistance characteristics and fitness of Gram-negative fecal bacteria from volunteers treated with minocycline or amoxicillin.

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    A yearlong study was performed to examine the effect of antibiotic administration on the bacterial gut flora. Gram-negative facultative anaerobic bacteria were recovered from the feces of healthy adult volunteers administered amoxicillin, minocycline or placebo, and changes determined in antimicrobial resistance (AMR) gene carriage. Seventy percent of the 1039 facultative anaerobic isolates recovered were identified by MALDI-TOF as Escherichia coli. A microarray used to determine virulence and resistance gene carriage demonstrated that AMR genes were widespread in all administration groups, with the most common resistance genes being bla TEM, dfr, strB, tet(A), and tet(B). Following amoxicillin administration, an increase in the proportion of amoxicillin resistant E. coli and a three-fold increase in the levels of bla TEM gene carriage was observed, an effect not observed in the other two treatment groups. Detection of virulence genes, including stx1A, indicated not all E. coli were innocuous commensals. Approximately 150 E. coli collected from 6 participants were selected for pulse field gel electrophoresis (PFGE), and a subset used for characterisation of plasmids and Phenotypic Microarrays (PM). PFGE indicated some E. coli clones had persisted in volunteers for up to 1 year, while others were transient. Although there were no unique characteristics associated with plasmids from persistent or transient isolates, PM assays showed transient isolates had greater adaptability to a range of antiseptic biocides and tetracycline; characteristics which were lost in some, but not all persistent isolates. This study indicates healthy individuals carry bacteria harboring resistance to a variety of antibiotics and biocides in their intestinal tract. Antibiotic administration can have a temporary effect of selecting bacteria, showing co-resistance to multiple antibiotics, some of which can persist within the gut for up to 1 year

    Friction force on slow charges moving over supported graphene

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    We provide a theoretical model that describes the dielectric coupling of a 2D layer of graphene, represented by a polarization function in the Random Phase Approximation, and a semi-infinite 3D substrate, represented by a surface response function in a non-local formulation. We concentrate on the role of the dynamic response of the substrate for low-frequency excitations of the combined graphene-substrate system, which give rise to the stopping force on slowly moving charges above graphene. A comparison of the dielectric loss function with experimental HREELS data for graphene on a SiC substrate is used to estimate the damping rate in graphene and to reveal the importance of phonon excitations in an insulating substrate. A signature of the hybridization between graphene's pi plasmon and the substrate's phonon is found in the stopping force. A friction coefficient that is calculated for slow charges moving above graphene on a metallic substrate shows an interplay between the low-energy single-particle excitations in both systems.Comment: 13 pages, 5 figures, submitted to Nanotechnology for a special issue related to the NGC 2009 conference (http://asdn.net/ngc2009/index.shtml

    Institutional Repository saber.ula.ve: A testimonial perspective

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    In this paper, we describe our decade-long experience of building and operating one of the most active Institutional Repository in the world: www.saber.ula.ve (University of the Andes, Merida-Venezuela). In order to share our experience with other institutions, we firstly explain the steps we followed to preserve and disseminate the scientific production of the University of Los Andes' researchers. We then present some recent quantitative results about our repository activities and we outline some methodological guidelines that could be applied in order to replicate similar experiences. These guidelines list the ingredients or building blocks as well as the processes followed for developing and maintaining the services of an Institutional Repository. These include technological infrastructure; institutional policies on preservation, publication and dissemination of knowledge; recommendations on incentives for open access publication; the process of selection, testing and adaptation of technological tools; the planning and organization of services, and the dissemination and support within the scientific community that will eventually lead to the adoption of the ideas that lie behind the open access movement. We summarize the results obtained regarding the acceptance, adoption and use of the technological tools used for the publication of our institution's intellectual production, and we present the main obstacles encountered on the way.Comment: 7th International Conference on Open Access in Accra Ghana from 2nd to 3rd November 200
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