Endovascular Treatment of Popliteal Artery Aneurysms

AbstractObjective. To present the results of the endovascular treatment of popliteal artery aneurysms.Methods. From April 1999 to January 2002, 11 patients, aged 40–94 years, with 12 popliteal aneurysms were treated. Nine (75%) underwent an endoluminal repair, of whom three were done emergently due to a aneurysm rupture. Aneurysm diameter was 28–105 (mean 69) mm. A Hemobahn stent graft was inserted in six, Wallgraft in two and Passager in one case.Results. During a mean follow-up of 14 (3–31) months, four (44%) thromboses occurred: two in the early postoperative period (30 days) and two during the late postoperative period. Two of the four occluded grafts were successfully reopened, and in the one a stenosis of the distal end of the stent graft was treated with balloon dilatation. Patency rates at 1 and 12 months were 64/47% (primary patency) and 88/75% (secondary patency), respectively.Conclusion. Initial experience with endovascular treatment of the popliteal aneurysm in high-risk patients yielded modest results. Larger number of patients and further follow-up time is necessary to evaluate the long-term results

Inflammatory pseudotumor of the liver: a case report and review of the literature

<p>Abstract</p> <p>Introduction</p> <p>Inflammatory pseudotumor of the liver represents a fairly uncommon pathology. Although it is a benign tumor, the correct diagnosis can be missed.</p> <p>Case presentation</p> <p>We report the case of a 55-year-old Caucasian man, who presented with a one-month history of abdominal pain and weight loss. He was diagnosed with a primary liver tumor by computed tomography and magnetic resonance imaging. Alpha-fetoprotein levels ranged within normal limits. A right posterior sectorectomy was performed. Histopathology revealed an inflammatory pseudotumor of the liver. Our patient remains in good condition one year later.</p> <p>Conclusion</p> <p>Although inflammatory pseudotumor of the liver is usually a benign process, controversy regarding its management still exists. With this case report we review the existing literature and consider hepatectomy as a safe treatment approach.</p

The Influence of Water Nitrate Concentration Combined with Elevated Temperature on Rainbow Trout <i>Oncorhynchus mykiss</i> in an Experimental Aquaponic Setup

Intensive recirculating systems are a fast-developing sector of aquaculture. While several warm-water fish have been reared in aquaponics, almost no data are available for cold-water species. The determination of nitrate toxicity thresholds in recirculating aquaculture is crucial. Different pollutants are typically more toxic at elevated temperatures. We investigated the performance of Oncorhynchus mykiss under two different nitrate levels and two temperatures. We applied a 2 × 2 factorial design, where fish (9.78 ± 0.51 g) were exposed to nitrate concentrations of 40 or 110 mg/L NO3− and to temperatures of 17 °C or 21 °C for 20 days. This study focused on understanding the physiological responses of rainbow trout to relatively low nitrate levels under heat stress in order to investigate the feasibility of integrating this species into commercial aquaponics. The growth, condition, and expression of genes involved in metabolism, heat shock, antioxidant, and immune response were assessed in the liver, together with the activities of enzymes related to glucose and fatty acid metabolism. High nitrate levels at 17 °C affected the condition but did not alter growth, leading to increased glycolytic potential and, occasionally, a greater reliance on lipid oxidation. Antioxidant defense was mainly induced due to high nitrates and the similar expression patterns of antioxidant genes observed under high nitrate at both 17 °C and 21 °C. Warm exposure decreased condition and growth, leading to greatly reduced glucokinase transcription, irrespective of the nitrate levels. Exposure to 21 °C and high nitrate led to equivalent growth and condition as well as to a milder inflammatory response combined with metabolic readjustments (enhancement of glycolytic and lipid oxidation pathways) compared to the low nitrates at 21 °C. Based on the results, rearing at a temperature close to 21 °C should be avoided for fingerling growth, while NO3− concentration until 110 mg/L may not have severe impacts on fingerling health and growth at 17 °C. In addition, rainbow trout fingerlings can tolerate a 20-day exposure at 21 °C and NO3− up to 110 mg/L. Additional factors should always be considered, such as specific water quality parameters, for a comprehensive approach to assessing the feasibility of rainbow trout aquaculture in aquaponics

A digital memristor emulator for FPGA-based artificial neural networks

FPGAs are reconfigurable electronic platforms, well-suited to implement complex artificial neural networks (ANNs). To this end, the compact hardware (HW) implementation of artificial synapses is an important step to obtain human brain-like functionalities at circuit-level. In this context, the memristor has been proposed as the electronic analogue of biological synapses, but the price of commercially available samples still remains high, hence motivating the development of HW emulators. In this work we present the first digital memristor emulator based upon a voltagecontrolled threshold-type bipolar memristor model. We validate its functionality in low-cost yet powerful FPGA families. We test its suitability for complex memristive circuits and prove its synaptic properties in a small associative memory via a perceptron ANN.Peer Reviewe

Power-efficient noise-Induced reduction of ReRAM cell’s temporal variability effects

Resistive Random Access Memory (ReRAM) is apromising novel memory technology for non-volatile storing, with low-power operation and ultra-high area density. However, ReRAM memories still face issues through commercialization, mainly owing to the fact that the high fabrication variations and the stochastic switching of the manufactured ReRAM devices cause high Bit Error Rate (BER). Given that ReRAM devices are nonlinear elements, the nonlinear phenomenon of Stochastic Resonance (SR), which defines that an input disturbance with specific characteristics can improve the total performance of the nonlinear system, is used to reduce the ReRAM cell’s BER. Thus, in this work, the BER of a single ReRAM cell is explored, using the Stanford PKU model, and is improved after the application of specific additive input noise. The power dissipation of the proposed approach is also evaluated and compared with the consideration of higher amplitude writing pulses in the lack of noise, showing that the proposed noiseinduced technique can decrease the BER without the excessive increase of the power dissipation. As a first step, towards the experimental verification of the proposed method, noise-induced measurements on a single fabricated ReRAM device are also performed. Overall, the presented results of the BER reduction with low power dissipation, reaching up to 3:26x less power consumption considering 100 ns writing pulses, are encouraging for ReRAM designers, delivering a circuit-level solution against the device-level problem.This work was supported in part by Spanish MICIU and MINECO under Projects TEC2016-75151-C3-R, TEC2017-90969-EXP and PID2019-103869RB-C3 and in part by FPI-UPC and partially supported by Greece-Russia bilateral joint research project MEM-Q (proj.no./MIS T4∆PΩ-00030/5021467) supported by GSRT, funded by National and European funds.Peer ReviewedPostprint (author's final draft

Aquaponics as a Promising Strategy to Mitigate Impacts of Climate Change on Rainbow Trout Culture

The impact of climate change on both terrestrial and aquatic ecosystems tends to become more progressively pronounced and devastating over the years. The sector of aquaculture is severely affected by natural abiotic factors, on account of climate change, that lead to various undesirable phenomena, including aquatic species mortalities and decreased productivity owing to oxidative and thermal stress of the reared organisms. Novel innovative technologies, such as aquaponics that are based on the co-cultivation of freshwater fish with plants in a sustainable manner under the context of controlled abiotic factors, represent a promising tool for mitigating the effect of climate change on reared fish. The rainbow trout (Oncorhynchus mykiss) constitutes one of the major freshwater-reared fish species, contributing to the national economies of numerous countries, and more specifically, to regional development, supporting mountainous areas of low productivity. However, it is highly vulnerable to climate change effects, mainly due to the concrete raceways, in which it is reared, that are constructed on the flow-through of rivers and are, therefore, dependent on water’s physical properties. The current review study evaluates the suitability, progress, and challenges of developing innovative and sustainable aquaponic systems to rear rainbow trout in combination with the cultivation of plants. Although not commercially developed to a great extent yet, research has shown that the rainbow trout is a valuable experimental model for aquaponics that may be also commercially exploited in the future. In particular, abiotic factors required in rainbow trout farming along, with the high protein proportion required in the ratios due to the strict carnivorous feeding behavior, result in high nitrate production that can be utilized by plants as a source of nitrogen in an aquaponic system. Intensive farming of rainbow trout in aquaponic systems can be controlled using digital monitoring of the system parameters, mitigating the obstacles originating from extreme temperature fluctuations