Time relaxation of interacting single--molecule magnets

We study the relaxation of interacting single--molecule magnets (SMMs) in both spatially ordered and disordered systems. The tunneling window is assumed to be, as in Fe8, much narrower than the dipolar field spread. We show that relaxation in disordered systems differs qualitatively from relaxation in fully occupied cubic and Fe_8 lattices. We also study how line shapes that develop in ''hole--digging'' experiments evolve with time t in these fully occupied lattices. We show (1) that the dipolar field h scales as t^p in these hole line shapes and show (2) how p varies with lattice structure. Line shapes are not, in general, Lorentzian. More specifically, in the lower portion of the hole, they behave as (h/t^p)^{(1/p)-1} if h is outside the tunnel window. This is in agreement with experiment and with our own Monte Carlo results.Comment: 21 LaTeX pages, 6 eps figures. Submitted to PRB on 15 June 2005. Accepted on 13 August 200

Targeting of the P2X7 receptor in pancreatic cancer and stellate cells

The ATP‐gated receptor P2X7 (P2X7R) is involved in regulation of cell survival and has been of interest in cancer field. Pancreatic ductal adenocarcinoma (PDAC) is a deadly cancer and new markers and therapeutic targets are needed. PDAC is characterized by a complex tumour microenvironment, which includes cancer and pancreatic stellate cells (PSCs), and potentially high nucleotide/side turnover. Our aim was to determine P2X7R expression and function in human pancreatic cancer cells in vitro as well as to perform in vivo efficacy study applying P2X7R inhibitor in an orthotopic xenograft mouse model of PDAC. In the in vitro studies we show that human PDAC cells with luciferase gene (PancTu‐1 Luc cells) express high levels of P2X7R protein. Allosteric P2X7R antagonist AZ10606120 inhibited cell proliferation in basal conditions, indicating that P2X7R was tonically active. Extracellular ATP and BzATP, to which the P2X7R is more sensitive, further affected cell survival and confirmed complex functionality of P2X7R. PancTu‐1 Luc migration and invasion was reduced by AZ10606120, and it was stimulated by PSCs, but not by PSCs from P2X7(‐/‐) animals. PancTu‐1 Luc cells were orthotopically transplanted into nude mice and tumour growth was followed noninvasively by bioluminescence imaging. AZ10606120‐treated mice showed reduced bioluminescence compared to saline‐treated mice. Immunohistochemical analysis confirmed P2X7R expression in cancer and PSC cells, and in metaplastic/neoplastic acinar and duct structures. PSCs number/activity and collagen deposition was reduced in AZ10606120‐treated tumours

Quantum oscillations of the magnetic torque in the nodal-line Dirac semimetal ZrSiS

We report a study of quantum oscillations (QO) in the magnetic torque of the nodal-line Dirac semimetal ZrSiS in the magnetic fields up to 35 T and the temperature range from 40 K down to 2 K, enabling high resolution mapping of the Fermi surface (FS) topology in the $k_z=\pi$ (Z-R-A) plane of the first Brillouin zone (FBZ). It is found that the oscillatory part of the measured magnetic torque signal consists of low frequency (LF) contributions (frequencies up to 1000 T) and high frequency (HF) contributions (several clusters of frequencies from 7-22 kT). Increased resolution and angle-resolved measurements allow us to show that the high oscillation frequencies originate from magnetic breakdown (MB) orbits involving clusters of individual $\alpha$ hole and $\beta$ electron pockets from the diamond shaped FS in the Z-R-A plane. Analyzing the HF oscillations we have unequivocally shown that the QO frequency from the dog-bone shaped Fermi pocket ($\beta$ pocket) amounts $\beta=591(15)$ T. Our findings suggest that most of the frequencies in the LF part of QO can also be explained by MB orbits when intraband tunneling in the dog-bone shaped $\beta$ electron pocket is taken into account. Our results give a new understanding of the novel properties of the FS of the nodal-line Dirac semimetal ZrSiS and sister compounds

Highly anisotropic interlayer magnetoresistance in ZrSiS nodal-line Dirac semimetal

We instigate the angle-dependent magnetoresistance (AMR) of the layered nodal-line Dirac semimetal ZrSiS for the in-plane and out-of-plane current directions. This material has recently revealed an intriguing butterfly-shaped in-plane AMR that is not well understood. Our measurements of the polar out-of-plane AMR show a surprisingly different response with a pronounced cusp-like feature. The maximum of the cusp-like anisotropy is reached when the magnetic field is oriented in the $a$-$b$ plane. Moreover, the AMR for the azimuthal out-of-plane current direction exhibits a very strong four-fold $a$-$b$ plane anisotropy. Combining the Fermi surfaces calculated from first principles with the Boltzmann's semiclassical transport theory we reproduce and explain all the prominent features of the unusual behavior of the in-plane and out-of-plane AMR. We are also able to clarify the origin of the strong non-saturating transverse magnetoresistance as an effect of imperfect charge-carrier compensation and open orbits. Finally, by combining our theoretical model and experimental data we estimate the average relaxation time of $2.6\times10^{-14}$~s and the mean free path of $15$~nm at 1.8~K in our samples of ZrSiS.Comment: 8 pages, 4 figure

Star-forming galaxies versus low- and high-excitation radio AGN in the VLA-COSMOS 3GHz Large Project

We study the composition of the faint radio population selected from the VLA-COSMOS 3GHz Large Project, a radio continuum survey performed at 10 cm wavelength. The survey covers the full 2 square degree COSMOS field with mean $rms\sim2.3$ $\mu$Jy/beam, cataloging 10,899 source components above $5\times rms$. By combining these radio data with UltraVISTA, optical, near-infrared, and Spitzer/IRAC mid-infrared data, as well as X-ray data from the Chandra Legacy, and Chandra COSMOS surveys, we gain insight into the emission mechanisms within our radio sources out to redshifts of $z\sim5$. From these emission characteristics we classify our souces as star forming galaxies or AGN. Using their multi-wavelength properties we further separate the AGN into sub-samples dominated by radiatively efficient and inefficient AGN, often referred to as high- and low-excitation emission line AGN. We compare our method with other results based on fitting of the sources' spectral energy distributions using both galaxy and AGN spectral models, and those based on the infrared-radio correlation. We study the fractional contributions of these sub-populations down to radio flux levels of $\sim$10 $\mu$Jy. We find that at 3 GHz flux densities above $\sim$400 $\mu$Jy quiescent, red galaxies, consistent with the low-excitation radio AGN class constitute the dominant fraction. Below densities of $\sim$200 $\mu$Jy star-forming galaxies begin to constitute the largest fraction, followed by the low-excitation, and X-ray- and IR-identified high-excitation radio AGN.Comment: 7 pages, 3 figures, The many facets of extragalactic radio surveys: towards new scientific challenges, Bologna 20-23 October 201

Spin Tunneling and Phonon-assisted Relaxation in Mn12-acetate

We present a comprehensive theory of the magnetization relaxation in a Mn12-acetate crystal in the high-temperature regime (T>1 K), which is based on phonon-assisted spin tunneling induced by quartic magnetic anisotropy and weak transverse magnetic fields. The overall relaxation rate as function of the longitudinal magnetic field is calculated and shown to agree well with experimental data including all resonance peaks measured so far. The Lorentzian shape of the resonances, which we obtain via a generalized master equation that includes spin tunneling, is also in good agreement with recent data. We derive a general formula for the tunnel splitting energy of these resonances. We show that fourth-order diagonal terms in the Hamiltonian lead to satellite peaks. A derivation of the effective linewidth of a resonance peak is given and shown to agree well with experimental data. In addition, previously unknown spin-phonon coupling constants are calculated explicitly. The values obtained for these constants and for the sound velocity are also in good agreement with recent data. We show that the spin relaxation in Mn12-acetate takes place via several transition paths of comparable weight. These transition paths are expressed in terms of intermediate relaxation times, which are calculated and which can be tested experimentally.Comment: 18 pages, 22 EPS figures, REVTe

Anomalous Behavior of the Contact Process with Aging

The effect of power-law aging on a contact process is studied by simulation and using a mean-field approach. We find that the system may approach its stationary state in a nontrivial, nonmonotonous way. For the particular value of the aging exponent, $\alpha=1$, we observe a rich set of behaviors: depending on the process parameters, the relaxation to the stationary state proceeds as $1/\ln t$ or via a power law with a nonuniversal exponent. Simulation results suggest that for $0<\alpha<1$, the absorbing-state phase transition is in the universality class of directed percolation.Comment: 4 pages revtex (twocolumn, psfig), 3 figure