Comparison of aqueous extracts of Citrus × aurantium and Aloe vera L. as fungistatic control of Fusarium spp

Objective: In this work, the fungistatic capacity of extracts obtained from Citrus × aurantium (sour orange) and Aloe vera, was evaluated on phytopathogenic fungi of the genus Fusarium sp. Design/methodology/approach: Three aqueous extracts were performed (aloe: peel, aloe: peel and gel, sour orange: peel). The ability to inhibition in the in vitro growth of a fusarium sp. ml, 500 µg/ml, 250 µg/ml, 1 mg/ml, 5 mg/ml, 10 mg/ml, 20 mg/ml, 50 mg/ml, 70 mg/ml and 100 mg/ml in each The extracts, a witness was added which was sterilized purified water, the radial creation was measured based on the infected disk to the edge of the mycelium diameter day by day. Results: The extracts that managed to obtain a good response in inhibition were the ethanolic extracts in concentrations of 100 and 70 mg of aloe in 1 ml of agar, the concentration of 70 mg of orange in 1 ml of agar and in the aqueous extract of aloe: Cascara and 100 mg concentration gel extract in 1.0 ml of agar Findings/conclusions: The aqueous aloe extract, proved to have inhibitory potential in the radial growth of fusarium of 47.5%.Objective: To evaluate the fungistatic capacity of aqueous extracts obtained from Citrus × aurantium (sour orange) and Aloe vera L. on phytopathogenic fungi of the genus Fusarium spp. Design/Methodology/Approach: Three aqueous extracts were made (aloe peel, aloe peel and gel, and sour orange peel). The inhibition capacity in the in vitro growth of a Fusarium spp. strain was measured using the following concentrations: 750 µg/mL, 500 µg/mL, 250 µg/mL, 1 mg/mL, 5 mg/mL, 10 mg/mL, 20 mg/mL, 50 mg/mL, 70 mg/mL, and 100 mg /mL in each extract. The control was sterile distilled water. The radial growth of the mycelium was measured daily, starting from the infected disc up to the edge of its diameter. Results: The following extracts recorded a good inhibitory response: 100- and 70-mg concentrations of aloe peel and gel in 1 mL of agar; 70-mg concentration of orange in 1 mL of agar; and 100-mg concentration of aloe peel in 1 mL of agar. Findings/Conclusions: The aqueous extract of aloe had a 47.5 % inhibitory potential in the radial growth of Fusarium

Maternal dietary patterns and acute leukemia in infants: results from a case control study in Mexico

BackgroundChildhood cancer is the leading cause of disease-related mortality among children aged 5–14 years in Mexico, with acute leukemia being the most common cancer among infants. Examining the overall dietary patterns allows for a comprehensive assessment of food and nutrient consumption, providing a more predictive measure of disease risk than individual foods or nutrients. This study aims to evaluate the association between maternal dietary patterns during pregnancy and the risk of acute leukemia in Mexican infants.MethodsA hospital-based case–control study was conducted, comparing 109 confirmed acute leukemia cases with 152 age-matched controls. All participants (≤24 months) were identified at hospitals in Mexico City between 2010 and 2019. Data on a posteriori dietary patterns and other relevant variables were collected through structured interviews and dietary questionnaires. Multivariate logistic regression was employed to estimate the association between maternal dietary patterns during pregnancy and the risk of acute leukemia in infants.ResultsThe “Balanced & Vegetable-Rich” pattern, characterized by a balanced consumption of various food groups and higher vegetable intake, exhibited a negative association with acute leukemia when compared to the “High Dairy & Cereals” Pattern (adjusted odds ratio [OR] = 0.51; 95% confidence interval [CI]: 0.29, 0.90). We observed that mothers who gave birth to girls and adhered to a healthy dietary pattern during pregnancy exhibited significantly lower odds of their children developing AL compared to those who gave birth to boys [OR = 0.32 (95% CI 0.11, 0.97)]. Our results underscore the significance of maternal nutrition as a modifiable factor in disease prevention and the importance of prenatal health education

Evidence of spatial clustering of childhood acute lymphoblastic leukemia cases in Greater Mexico City: report from the Mexican Inter-Institutional Group for the identification of the causes of childhood leukemia

BackgroundA heterogeneous geographic distribution of childhood acute lymphoblastic leukemia (ALL) cases has been described, possibly, related to the presence of different environmental factors. The aim of the present study was to explore the geographical distribution of childhood ALL cases in Greater Mexico City (GMC).MethodsA population-based case-control study was conducted. Children <18 years old, newly diagnosed with ALL and residents of GMC were included. Controls were patients without leukemia recruited from second-level public hospitals, frequency-matched by sex, age, and health institution with the cases. The residence address where the patients lived during the last year before diagnosis (cases) or the interview (controls) was used for geolocation. Kulldorff’s spatial scan statistic was used to detect spatial clusters (SCs). Relative risks (RR), associated p-value and number of cases included for each cluster were obtained.ResultsA total of 1054 cases with ALL were analyzed. Of these, 408 (38.7%) were distributed across eight SCs detected. A relative risk of 1.61 (p<0.0001) was observed for the main cluster. Similar results were noted for the remaining seven ones. Additionally, a proximity between SCs, electrical installations and petrochemical facilities was observed.ConclusionsThe identification of SCs in certain regions of GMC suggest the possible role of environmental factors in the etiology of childhood ALL

Ciencia Odontológica 2.0

Libro que muestra avances de la Investigación Odontológica en MéxicoEs para los integrantes de la Red de Investigación en Estomatología (RIE) una enorme alegría presentar el segundo de una serie de 6 libros sobre casos clínicos, revisiones de la literatura e investigaciones. La RIE está integrada por cuerpos académicos de la UAEH, UAEM, UAC y UdeG

Control of carotenoid gene expression in Bixa orellana L. leaves treated with norflurazon

Bixa orellana (annatto or lipstick tree) is a perennial tropical plant that stores and produces considerable quantities of the apocarotenoid bixin, a culturally and economically important pigment used worldwide. However, the mechanisms underlying the gene regulation and pigment accumulation of bixin and carotenoids in annatto remain unknown. Bixin is present in the different tissues of the plant, although this pigment is primarily accumulated in the seed coat. Thus, the leaves are useful organs for understanding carotenoid and bixin production, thereby facilitating the study of this pigment, which would otherwise be difficult in ligneous adult plants. To study the regulation of bixin synthesis and to determine which genes are important regulatory molecules at the transcription level, the herbicide norflurazon (NF) was used to block carotenoid synthesis and bixin concentrations in B. orellana leaves. The genes activated in the early stages of the carotenoid pathway are involved in lycopene production (dxs, psy and pds), and those induced in the later stages of the carotenoid pathway, such as β and ε-lycopene cyclases and boccd1, were differentially expressed compared with the control. The expression of some genes was more susceptible to certain concentrations of NF, potentially reflecting the roles of these genes in carotenoid synthesis in B. orellana. These results suggest that apocarotenoids, such as bixin, are synthesized using alternative precursors through the actions of genes that have not yet been identified

Hitos demográficos del siglo XXI : envejecimiento. Tomo I

Es posible afirmar que en pleno siglo XXI la población tiene una vida más prolongada debido a la mejora en los adelantos médicos y atención en salud, educación y en lo relativo al bienestar económico. Sin embargo, el envejecimiento poblacional lleva consigo desafíos políticos, económicos, sociales y culturales. Dar cuenta de este proceso social ha requerido y seguirá requiriendo de investigaciones y estudios que expliquen los factores determinantes que confluyen en esta circunstancia,y aporten elementos para abordar de la mejor manera los aspectos que tienen que ver con la calidad de vida en esta última etapa de la existencia de las personas. Esto convierte al envejecimiento demográfico en un asunto de Estado.Sin duda estos procesos de cambios demográficos están transformando el panorama social que habrá de modificar las políticas públicas hacia estos grupos de edad

Historia medieval: Siglos III a XV

Historia medieval: siglos III a XV es un manual pensado por el Grupo de Investigación y Estudios Medievales del Centro de Estudios Históricos de la Facultad de Humanidades de la Universidad Nacional de Mar del Plata (República Argentina) en función de las necesidades de los estudiantes universitarios argentinos, que se enfrentan al estudio de la Edad Media desde una doble perspectiva universal -priorizando el Occidente medieval- y general -un conocimiento de conjunto de los temas estudiados- a la vez. De allí su estructuración por siglos y por cuestiones (políticas, sociales, económicas y culturales).Fil: Asla, Alberto Oscar. Universidad Nacional de Mar del Plata. Facultad de Humanidades. Departamento de Historia. Centro de Estudios Históricos; ArgentinaFil: Asiss González, Federico Javier. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - San Juan; Argentina. Universidad Nacional de San Juan. Facultad de Filosofía, Humanidades y Artes. Departamento de Historia; ArgentinaFil: Ávila, Claudio. Universidad Nacional de Mar del Plata. Facultad de Humanidades. Departamento de Historia. Centro de Estudios Históricos; ArgentinaFil: Báez, Adriana. Universidad Nacional de Salta; ArgentinaFil: Bahr, María Cecilia. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Pontificia Universidad Católica Argentina "Santa María de los Buenos Aires"; ArgentinaFil: Basualdo Miranda, Hugo Roberto. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - San Juan; Argentina. Universidad Nacional de San Juan. Facultad de Filosofía, Humanidades y Artes. Departamento de Historia; ArgentinaFil: Beccar, Julieta. Pontificia Universidad Católica Argentina "Santa María de los Buenos Aires"; ArgentinaFil: Beraldi, Lucía. Pontificia Universidad Católica Argentina "Santa María de los Buenos Aires"; ArgentinaFil: Carbó, Laura Marcela. Universidad Nacional de Mar del Plata. Facultad de Humanidades. Departamento de Historia. Centro de Estudios Históricos; ArgentinaFil: Coria, María Verónica. Universidad Nacional de Mar del Plata. Facultad de Humanidades. Departamento de Historia. Centro de Estudios Históricos; Argentina. Universidad Nacional de San Juan. Facultad de Filosofía, Humanidades y Artes. Departamento de Historia; ArgentinaFil: Coronado Schwindt, Gisela Beatriz. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Nacional de Mar del Plata. Facultad de Humanidades. Departamento de Historia. Centro de Estudios Históricos; ArgentinaFil: Corrales, Julio César. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Nacional de Mar del Plata. Facultad de Humanidades. Departamento de Historia. Centro de Estudios Históricos; ArgentinaFil: Díaz Duckwen, María Luján. Universidad Nacional de Mar del Plata. Facultad de Humanidades. Departamento de Historia. Centro de Estudios Históricos; ArgentinaFil: Garofalo, Hernán Miguel. Universidad Nacional de Mar del Plata. Facultad de Humanidades. Departamento de Historia. Centro de Estudios Históricos; ArgentinaFil: Gerardi, Juan Manuel. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Nacional de Mar del Plata. Facultad de Humanidades. Departamento de Historia. Centro de Estudios Históricos; ArgentinaFil: Giordano, Gustavo. Universidad Nacional de Rosario; ArgentinaFil: González, María Alejandra. Universidad Nacional de Mar del Plata. Facultad de Humanidades. Departamento de Historia. Centro de Estudios Históricos; ArgentinaFil: Gugliotta, Pablo. Universidad Nacional de Mar del Plata. Facultad de Humanidades. Departamento de Historia. Centro de Estudios Históricos; ArgentinaFil: Mondragón, Silvina Andrea. Universidad Nacional de Mar del Plata. Facultad de Humanidades. Departamento de Historia. Centro de Estudios Históricos; ArgentinaFil: Neyra, Andrea Vanina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Nacional de Mar del Plata. Facultad de Humanidades. Departamento de Historia. Centro de Estudios Históricos; ArgentinaFil: Paci, Teresa Emilia. Universidad Nacional de San Juan. Facultad de Filosofía, Humanidades y Artes. Departamento de Historia; ArgentinaFil: Rodríguez, Gerardo Fabián. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Nacional de Mar del Plata. Facultad de Humanidades. Departamento de Historia. Centro de Estudios Históricos; ArgentinaFil: Rigueiro García, Jorge. Universidad de Buenos Aires; ArgentinaFil: Vidaurre, Norma Inés. Universidad Nacional de San Juan. Facultad de Filosofía, Humanidades y Artes. Departamento de Historia; ArgentinaFil: Zapatero, Mariana Paola. Pontificia Universidad Católica Argentina "Santa María de los Buenos Aires"; Argentin

Table_1_Evidence of spatial clustering of childhood acute lymphoblastic leukemia cases in Greater Mexico City: report from the Mexican Inter-Institutional Group for the identification of the causes of childhood leukemia.xlsx

BackgroundA heterogeneous geographic distribution of childhood acute lymphoblastic leukemia (ALL) cases has been described, possibly, related to the presence of different environmental factors. The aim of the present study was to explore the geographical distribution of childhood ALL cases in Greater Mexico City (GMC).MethodsA population-based case-control study was conducted. Children ResultsA total of 1054 cases with ALL were analyzed. Of these, 408 (38.7%) were distributed across eight SCs detected. A relative risk of 1.61 (pConclusionsThe identification of SCs in certain regions of GMC suggest the possible role of environmental factors in the etiology of childhood ALL.</p

Memorias semana de la Facultad de Educación. VII semana: historias, saberes y prácticas educativas innovadoras e incluyentes.

Las Memorias de la VII Semana de la Educación “Historias, saberes y prácticas educativas innovadoras e incluyentes”, publicadas por la Editorial de la Corporación Universitaria Minuto de Dios – UNIMINUTO, reúnen las ponencias y resúmenes sobre esta temática presentadas en un evento de realización anual, cuyo propósito es socializar experiencias investigativas y académicas de grupos, semilleros de investigación y trabajos de grado entre estudiantes y profesores de la Facultad de Educación, y con profesores y estudiantes de otras instituciones educativas que gentilmente compartieron experiencias en el campo de la educación, la pedagogía, el arte, la cultura y el deporte. El principal interés de este encuentro radica en recoger la construcción histórica educativa de la Corporación Universitaria Minuto de Dios – UNIMINUTO con respecto a sus orígenes y construcciones académicas; y las experiencias históricas de otras propuestas educativas a nivel de la educación infantil, básica, media y superior con tejido cultural y social, desde un enfoque diferencial y diverso en el cual todas las experiencias enriquecen la formación de maestros desde la innovación e inclusión en los diferentes contextos. En este encuentro participaron las universidades Antonio Nariño, de la Amazonia, del Rosario, La Gran Colombia y Pedagógica Nacional, así como la Corporación Escuela Pedagógica Experimental, el Centro Educativo de Nuestra Señora de la Paz, el Instituto Colombo Sueco y varios docentes de la Secretaría de Educación Distrital de Bogotá D. C

Mis casos Clínicos de Odontopediatría y Ortodoncia

Libro que conjunta casos en el área de Odontopediatría y OrtodonciaEs para los integrantes de la Red de Investigación en Estomatología (RIE) una enorme alegría presentar el tercer libro del 2021, sobre casos clínicos, revisiones de la literatura e investigaciones. La RIE está integrada por cuerpos académicos de la UAEH, UAEM, UAC y UdeG