Analysis of the quark sector in the 2HDM-III with a four-zero Yukawa texture using the most recent data on the CKM matrix

In this letter we analyse, in the context of the general 2-Higgs Doublet Model, the structure of the Yukawa matrices, $\widetilde{ \bf Y}_{ _{1,2} }^{q}$, by assuming a four-zero texture ansatz for their definition. In this framework, we obtain compact expressions for $\widetilde{ \bf Y}_{ _{1,2} }^{q}$, which are reduced to the Cheng and Sher ansatz with the difference that they are obtained naturally as a direct consequence of the invariants of the fermion mass matrices. Furthermore, in order to avoid large flavour violating effects coming from charged Higgs exchange, we consider the main flavour constraints on the off-diagonal terms of Yukawa texture {{$\left( \widetilde{\chi}_{j}^q \right)_{kl}$}} ($k\neq l$). We perform a $\chi^2$-fit based on current experimental data on the quark masses and the Cabibbo-Kobayashi-Maskawa mixing matrix ${ \bf V}_{\rm CKM }$. Hence, we obtain the allowed ranges for the parameters $\widetilde{ \bf Y}_{ _{1,2} }^{q}$ at 1$\sigma$ for several values of $\tan \beta$. The results are in complete agreement with the bounds obtained taking into account constraints on Flavour Changing Neutral Currents reported in the literature.Comment: 12 pages, 1 figure. Version accepted in Phys. Lett.

Windows through the Dusty Disks Surrounding the Youngest Low Mass Protostellar Objects

The formation and evolution of young low mass stars are characterized by important processes of mass loss and accretion ocurring in the innermost regions of their placentary circumstellar disks. Because of the large obscuration of these disks at optical and infrared wavelengths in the early protostellar stages (Class 0 Sources), they were previously detected only at radio wavelengths using interferometric techniques. We have detected with the Infrared Space Observatory (ISO) the mid-infrared emission associated with the Class 0 protostar VLA1 in the HH1-2 region located in the Orion nebula. The emission arises in the three wavelength windows at 5.3, 6.6 and 7.5 micras where the absorption due to ices and silicates has a local minimum that exposes the central parts of the youngest protostellar systems to mid-infrared investigations. The mid-infrared emission arises from a central source with 4 AU diameter at an averaged temperature of 700 K, deeply embedded in a dense region with a visual extinction of Av=80-100mag.Comment: The article is here and on pres

Tracing the energetics and evolution of dust with Spitzer : a chapter in the history of the Eagle Nebula

Context. The Spitzer GLIMPSE and MIPSGAL surveys have revealed a wealth of details about the Galactic plane in the infrared (IR)with orders of magnitude higher sensitivity, higher resolution, and wider coverage than previous IR observations. The structure of the interstellar medium (ISM) is tightly connected to the countless star-forming regions. We use these surveys to study the energetics and dust properties of the Eagle Nebula (M16), one of the best known star-forming regions. Aims. We present MIPSGAL observations of M16 at 24 and 70 μm and combine them with previous IR data. The mid-IR image shows a shell inside the well-known molecular borders of the nebula, as in the ISO and MSX observations from 15 to 21 μm. The morphologies at 24 and 70 μm are quite different, and its color ratio is unusually warm. The far-IR image resembles the one at 8 μm that enhances the structure of the molecular cloud and the "pillars of creation". We use this set of IR data to analyze the dust energetics and properties within this template for Galactic star-forming regions. Methods. We measure IR spectral energy distributions (SEDs) across the entire nebula, both within the inner shell and the photodissociation regions (PDRs).We use the DUSTEM model to fit these SEDs and constrain the dust temperature, the dust-size distribution, and the radiation field intensity relative to that provided by the star cluster NGC 6611 (χ/χ0). Results. Within the PDRs, the inferred dust temperature (~35 K), the dust-size distribution, and the radiation field intensity (χ/χ0 < 1) are consistent with expectations. Within the inner shell, the dust is hotter (~70 K). Moreover, the radiation field required to fit the SED is larger than that provided by NGC 6611 (χ/χ0 > 1). We quantify two solutions to this problem: (1) The size distribution of the dust in the shell is not that of interstellar dust. There is a significant enhancement of the carbon dust-mass in stochastically heated very small grains. (2) The dust emission arises from a hot (~10^6 K) plasma where both UV and collisions with electrons contribute to the heating. Within this hypothesis, the shell SED may be fit for a plasma pressure p/k ~ 5 × 10^7 K cm^(−3). Conclusions. We suggest two interpretations for the M16 inner shell: (1) The shell matter is supplied by photo-evaporative flows arising from dense gas exposed to ionized radiation. The flows renew the shell matter as it is pushed out by the pressure from stellar winds. Within this scenario, we conclude that massive-star forming regions such as M16 have a major impact on the carbon dustsize distribution. The grinding of the carbon dust could result from shattering in grain-grain collisions within shocks driven by the dynamical interaction between the stellar winds and the shell. (2) We also consider a more speculative scenario where the shell is a supernova remnant. In this case, we would be witnessing a specific time in the evolution of the remnant where the plasma pressure and temperature would enable the remnant to cool through dust emission

Flavor violating decays of the Higgs bosons in the THDM-III

We calculate the branching ratios for the decays of neutral Higgs bosons ($h^{0},H^{0},A^{0}$) into pairs of fermions, including flavor violating processes, in the context of the General Two Higgs Doublet Model III.Comment: 23 pages, 10 figures, 6 tables. Text clarifying equations and references added, typos correction

Microarray analysis of relative gene expression stability for selection of internal reference genes in the rhesus macaque brain

Abstract Background Normalization of gene expression data refers to the comparison of expression values using reference standards that are consistent across all conditions of an experiment. In PCR studies, genes designated as "housekeeping genes" have been used as internal reference genes under the assumption that their expression is stable and independent of experimental conditions. However, verification of this assumption is rarely performed. Here we assess the use of gene microarray analysis to facilitate selection of internal reference sequences with higher expression stability across experimental conditions than can be expected using traditional selection methods. We recently demonstrated that relative gene expression from qRT-PCR data normalized using GAPDH, ALG9 and RPL13A expression values mirrored relative expression using quantile normalization in Robust Multichip Analysis (RMA) on the Affymetrix® GeneChip® rhesus Macaque Genome Array. Having shown that qRT-PCR and Affymetrix® GeneChip® data from the same hormone replacement therapy (HRT) study yielded concordant results, we used quantile-normalized gene microarray data to identify the most stably expressed among probe sets for prospective internal reference genes across three brain regions from the HRT study and an additional study of normally menstruating rhesus macaques (cycle study). Gene selection was limited to 575 previously published human "housekeeping" genes. Twelve animals were used per study, and three brain regions were analyzed from each animal. Gene expression stabilities were determined using geNorm, NormFinder and BestKeeper software packages. Results Sequences co-annotated for ribosomal protein S27a (RPS27A), and ubiquitin were among the most stably expressed under all conditions and selection criteria used for both studies. Higher annotation quality on the human GeneChip® facilitated more targeted analysis than could be accomplished using the rhesus GeneChip®. In the cycle study, multiple probe sets annotated for actin, gamma 1 (ACTG1) showed high signal intensity and were among the most stably expressed. Conclusions Using gene microarray analysis, we identified genes showing high expression stability under various sex-steroid environments in different regions of the rhesus macaque brain. Use of quantile-normalized microarray gene expression values represents an improvement over traditional methods of selecting internal reference genes for PCR analysis

New ATCA, ALMA and VISIR observations of the candidate LBV SK-67266 (S61): the nebular mass from modelling 3D density distributions

We present new observations of the nebula around the Magellanic candidate Luminous Blue Variable S61. These comprise high-resolution data acquired with the Australia Telescope Compact Array (ATCA), the Atacama Large Millimetre/Submillimetre Array (ALMA), and VISIR at the Very Large Telescope (VLT). The nebula was detected only in the radio, up to 17 GHz. The 17 GHz ATCA map, with 0.8 arcsec resolution, allowed a morphological comparison with the H$\alpha$ Hubble Space Telescope image. The radio nebula resembles a spherical shell, as in the optical. The spectral index map indicates that the radio emission is due to free-free transitions in the ionised, optically thin gas, but there are hints of inhomogeneities. We present our new public code RHOCUBE to model 3D density distributions, and determine via Bayesian inference the nebula's geometric parameters. We applied the code to model the electron density distribution in the S61 nebula. We found that different distributions fit the data, but all of them converge to the same ionised mass, ~0.1 $\rm M\odot$, which is an order of magnitude smaller than previous estimates. We show how the nebula models can be used to derive the mass-loss history with high-temporal resolution. The nebula was probably formed through stellar winds, rather than eruptions. From the ALMA and VISIR non-detections, plus the derived extinction map, we deduce that the infrared emission observed by space telescopes must arise from extended, diffuse dust within the ionised region.Comment: 17 pages, 9 figures. Authors list corrected. In press in MNRAS. RHOCUBE code available online ( https://github.com/rnikutta/rhocube

The X-ray Luminosities of HH Objects

The recent detection of X-ray emission from HH 2 and HH 154 with the Chandra and XMM-Newton satellites (respectively) have opened up an interesting, new observational possibility in the field of Herbig-Haro objects. In order to be able to plan further X-ray observations of other HH objects, it is now of interest to be able to estimate their X-ray luminosities in order to choose which objects to observe. This paper describes a simple, analytic model for predicting the X-ray luminosity of a bow shock from the parameters of the flow (i.e., the size of the bow shock, its velocity, and the pre-shock density). The accuracy of the analytic model is analyzed through a comparison with the predictions obtained from axisymmetric, gasdynamic simulations of the leading working surface of an HH jet. We find that our analytic model reproduces the observed X-ray luminosities of HH 2 and HH 154, and we propose that HH~80/81 is a good candidate for future observations with Chandra.Comment: 10 pages (8 text, 2 figures

A mid-IR survey of the L 1641-N region with ISOCAM

We present an analysis of the L 1641 outflow region using broad-band and narrow-band imaging data at mid-infrared wavelengths from ISOCAM. We detect a total of 34 sources in the $7.65^{\prime}$ x $8.40^{\prime}$ region covered by the broad-band filters. Four of these sources have no reported detection in previous studies of the region. We find that the source previously identified as the near-IR counter-part to the IRAS detected point-source (IRAS 05338-0624) is not the brightest source in the wavelength region of the IRAS 12 \micron\ filter. We find instead that a nearby object (within the beam of IRAS and not detected at near-IR wavelengths) outshines all others sources in the area by a factor of $\sim$2. We submit that this source is likely to be the IRAS detected point source. A comparison of the near-IR (J-H vs H-K) and mid-IR (J-K vs [6.7 um]-[14 um]) color-color plots shows only four sources with excess emission at near-IR wavelengths, but atleast 85% of all sources show excess emission at mid-IR wavelengths. The CVF spectra suggest a range of evolutionary status in the program stars ranging from embedded YSOs to the young disks. When combined with optical and near-IR age estimates, these results show active current star-formation in the region that has been on-going for at least 2 Myr.Comment: Submitted to ApJ. Abstracted edited for arXiv submission Replaced by version accepted by Ap