57 research outputs found
The Impact of Oral Health on Taste Ability in Acutely Hospitalized Elderly
Objective: To investigate to what extent various oral health variables are associated with taste ability in acutely hospitalized elderly. Background: Impaired taste may contribute to weight loss in elderly. Many frail elderly have poor oral health characterized by caries, poor oral hygiene, and dry mouth. However, the possible influence of such factors on taste ability in acutely hospitalized elderly has not been investigated. Materials and Methods: The study was cross-sectional. A total of 174 (55 men) acutely hospitalized elderly, coming from their own homes and with adequate cognitive function, were included. Dental status, decayed teeth, oral bacteria, oral hygiene, dry mouth and tongue changes were recorded. Growth of oral bacteria was assessed with CRTH Bacteria Kit. Taste ability was evaluated with 16 taste strips impregnated with sweet, sour, salty and bitter taste solutions in 4 concentrations each. Correct identification was given score 1, and maximum total taste score was 16. Results: Mean age was 84 yrs. (range 70â103 yrs.). Total taste score was significantly and markedly reduced in patients with decayed teeth, poor oral hygiene, high growth of oral bacteria and dry mouth. Sweet and salty taste were particularly impaired in patients with dry mouth. Sour taste was impaired in patients with high growth of oral bacteria. Conclusion: This study shows that taste ability was reduced in acutely hospitalized elderly with caries activity, high growt
Advances in the behavioural and public health aspects of periodontitis: Group D Consensus report of the fifth European workshop in periodontology
The Fifth European Workshop on Periodontology: Etiology and Pathogenesis Leading to Preventive Concepts. Charterhouse at Ittingen, Thurgau, Switzerland, 5-9 February 2005. In Journal of Clinical Periodontology, 200
Estrogen regulates DNA synthesis in human gingival epithelial cells displaying strong estrogen receptor ÎČ immunoreactivity.
Nebel D, Bratthall G, Ekblad E, Norderyd O, Nilsson B-O. Estrogen regulates DNA synthesis in human gingival epithelial cells displaying strong estrogen receptor ÎČ immunoreactivity. J Periodont Res 2011; doi: 10.1111/j.1600-0765.2011.01382.x. © 2011 John Wiley & Sons A/S Background and Objective: Estrogen acts via estrogen receptor (ER) α and ÎČ. The expression pattern of ERs and their importance in gingival tissues are not fully understood. In this study, we investigate gingival ER expression and effects of estrogen on gingival epithelial cell proliferation. Material and Methods: Gingival biopsies were obtained from both healthy and diseased sites in three male and three female subjects. Expression of ERα and ÎČ was determined by immunohistochemistry. Effects of 17ÎČ-estradiol (E(2) ) on cell proliferation, monitored by measuring DNA synthesis, were studied in cultured human gingival epithelial HGEPp.05 cells. Results: Estrogen receptor ÎČ, but not ERα, immunoreactivity was demonstrated in nuclei of epithelial cells in all layers of the gingival epithelium, but also in cells of the lamina propria. No differences were observed between male and female subjects. The same pattern, i.e. high ERÎČ expression but no ERα expression, was observed in both healthy and diseased sites within each individual. No differences in the intensity of the ERÎČ immunoreactive signal and the number of ERÎČ-positive nuclei were observed between healthy and diseased gingiva. Treatment with a physiological concentration of E(2) (10 nm) had no effect on DNA synthesis in ERÎČ- and ERα-expressing HGEPp.05 cells. In contrast, E(2) at high concentrations (500 nm and 10 ÎŒm) reduced DNA synthesis by 60-70%. Conclusion: Human gingival epithelial cells display strong ERÎČ but low ERα immunoreactivity both in vivo and in culture. Estrogen attenuates gingival epithelial cell DNA synthesis at high but not low concentrations, suggesting a concentration-dependent mechanism
Oral health-related quality of life and associated factors among older people in short-term care
Objectives It is well known that oral health status is associated with oral healthârelated quality of life (OHRQoL) in the general population. The aim of this study was to describe and analyse OHRQoL among older people in shortâterm care and its associated factors. Materials and Methods This crossâsectional study included 391 older people in 36 shortâterm care units. Data were collected via clinical oral assessments, questions about selfâperceived oral and general health, Katz Index of Activities of Daily Living (KatzâADL) and the Revised Oral Assessment Guide (ROAG). OHRQoL was measured using the Oral Health Impact Profile (OHIPâ14). Multivariate logistic regression models were applied in the analysis. Results Poor OHRQoL was reported by 34% of the older people. Associated factors were swallowing problems according to ROAG; quite poor/poor selfâperceived physical, psychological and oral health; and being a woman. Conclusions There is an association between OHRQoL and older people's selfâperceived health according to the OHIPâ14. This indicates the importance of early detection of oral health problems in frail older people and to assess both oral health and swallowing problems among older people in shortâterm care
Soluble urokinaseâtype plasminogen activator receptor is associated with signs of periodontitis in adolescents
Influences of behaviour and attitude on education related inequality in tooth loss: findings from Norway and Sweden over 5 years of follow- up
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